or any other pain relief with to help.I am being treated for poss trapped nerve or slipped disc,waiting for scan
Hello nigelpatrickson, & welcome to the site. I am not sure either of the drugs you have listed. The two I come up with are Morphine SR & Codimal. Here are the results if this is correct:
Drug interactions for the following 2 drug(s):
Morphine Sulfate SR (morphine)
Interactions between your selected drugs
chlorpheniramine ↔ morphine
Applies to: Codimal (acetaminophen/chlorpheniramine/pseudoephedrine), Morphine Sulfate SR (morphine)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Other drugs that your selected drugs interact with
•Codimal (acetaminophen/chlorpheniramine/pseudoephedrine) interacts with more than 400 other drugs.
•Morphine Sulfate SR (morphine) interacts with more than 300 other drugs.
Interactions between your selected drugs and food
morphine ↔ food
Applies to: Morphine Sulfate SR (morphine)
GENERALLY AVOID: The central nervous system-depressant effects of morphine and alcohol may be additive. The combination may result in additive CNS-depression and impairment of judgment, thinking, and psychomotor skills. In more severe cases, respiratory depression, hypotension, profound sedation, and coma can occur.
GENERALLY AVOID: Consumption of alcohol while taking some sustained-release formulations of morphine may cause rapid release of the drug, resulting in high systemic levels of morphine that may be potentially lethal. Alcohol apparently can disrupt the release mechanism of some sustained-release formulations. The interaction was observed in in vitro studies using a 24-hour morphine formulation (Avinza 30 mg capsule, available in the U.S. from Ligand Pharmaceuticals). When the capsule was mixed with 900 mL of buffer solutions containing ethanol 20% and 40%, the dose of morphine that was released was alcohol concentration-dependent, leading to a more rapid release of morphine. Although the clinical relevance of this finding is unknown, 'dose-dumping' into the bloodstream is conceivable.
MANAGEMENT: Until more information is available, patients taking sustained-release formulations of morphine should not consume alcohol or use medications that contain alcohol. In general, potent narcotics such as morphine should not be combined with alcohol.
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Do not stop taking any medications without consulting your healthcare provider.
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