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I am taking keppra for left temporal lobe epilepsy. Can I take tramadol with this?

Responses (2)

Anonymous 14 Mar 2012


Interactions between your selected drugs

tramadol ↔ levetiracetam
Applies to: tramadol, Keppra (levetiracetam)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Other drugs that your selected drugs interact with

tramadol interacts with more than 300 other drugs.
Keppra (levetiracetam) interacts with more than 100 other drugs.

Interactions between your selected drugs and food

No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.,1448-858

Take care,


rockgal81 14 Mar 2012

I'm not sure I'd take Tramadol if you have epilepsy. I'm not sure whether it's because of it's opiod effects or it's SNRI effects, but it lowers the threshold for seizures in people that have them. From a personal perspective, I wouldn't take it at all. I became very dependent on them and they actually caused me to have a few seizures.

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