How does one deal with the side effect of acid reflex caused by my ADHD medication Adderall? I changed my medication recently and I think the adderall is messing with my stomach. I have had severe acid reflex twice since I started this medication on the 7th of November. I mean so bad that it wouldn’t stop for a couple hours even after taken antacid. Also I have never had acid reflex this bad. I get it maybe once a year and that’s it.