... I experience trouble with my breathing when trying to exercise and more recently, severe cramping in my calves and my upper thighs seem to turn into jelly and feel as though they are going to give way . An absolute nightmare !! I have had tests for LVH which have come back clear . I am waiting for an appt with the Dr to discuss further tests . I am convinced my cocktail of drugs are having some adverse effects on my health . Has anyone else taking mycophenolate had similar effects ?