Your question isn't clear. There's probably less harm if you take smaller doses of tadalafil in a 24 hr. period than if you take it all at once. The further apart the doses are the better for your heart. The drug is also less likely to work.
Often men with high blood pressure (HBP) need help sustaining an erection. They may take tadalafil to increase their BP in order to allow blood to fill their penis which gives them that erection they want. The danger is for men taking medicine for HBP to take tadalafil to increase their BP and thus counteract or "neutralize" the HBP medicine. Now the risk of cardiac (heart) problems is much higher than if the man hadn't taken the tadalafil.
Note the many cardiac side effects, including death, that occur as tadalafil side effects at this link:
This is why many Drs. who prescribe HBP meds won't prescribe tadalafil. It's something to think about.
- Tadalafil Information for Consumers
- Tadalafil Information for Healthcare Professionals (includes dosage details)
- Side Effects of Tadalafil (detailed)
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