I have SLE, RA, Raynaud's, and Epilepsy and I am still not able to get my lupus under control, I am willing to try new methods of therapy but it is hard with all my differant conditions, now and for the past five year's I have been treated with methotrexate, and prednisone. I was on plaquenil for three years before my doctor decided that it was having no effect on the disease any recomendations are apreciated thank you.