I've been taking Paxil for +/-20 years and it's not working for me anymore. I recently had the genetic testing to help determine what Rx would work best for me and both Pristiq and Fetzima were recommended. Doc wants me to stop Paxil (no taper) and start taking Fetzima. I'm really nervous about stopping Paxil abruptly. Is there any indication that Fetzima will prevent withdrawal from Paxil? My schedule is very busy and I do a lot of driving. Worried about switching, but need to do something about depression and anxiety. Any input will be appreciated.