I am new to the group and have read so many amazing stories in support of chronic pain sufferers, you guys are so helpful. I need your help/advice on my "trial" to Fentanyl patches and what I am having issues with. I saw only my family physician from 2000 until Feb 2016 and then went to our new Pain Clinic. I have Chronic migraines, Fibromyalgia, Sciatica, Bursitis, DDD and inoperable damage to my L3-4-5-6. My doctor came up with this "routine" of meds and it worked for awhile but after all these years I never changed doses or upped my meds, I suffered in silence. I have been on 80 mg Oxycontin daily with 4 mg Dilaudid for bt pain along with 10 mg x3 Diazepam, 50 mg Phenergan 2x, 350 mg Soma 2x with anti-inflammatory and anti-seizure meds plus I get trigger injections every month. My PC Dr decided I should try using 50 mcg Fentanyl patches in place of the 80 mg Oxy, I'm in my 2nd week. I have the Duralgesic brand and my first problem came when they wouldn't stick, thru your advice I learned how to tape them on properly. My biggest issue is they don't seem to last the 72 hrs, more like 48 and I'm not getting enough relief. I know my tolerance has built up over the years and I am trying to determine if I need to go to the 75 mcg in 48 hrs or switch back to the Oxy, which I really don't want to do. Does anyone have the same 48 hr issue? What dosage better compares with the Oxy, 50 or 75 mcg? Any help would be appreciated. PS - for those switching, I've had no wd's from the Oxy at all. Thanks