I've been on zoloft for 11 years and these past couple years I've been having ups and downs with my anxiety. They've added Remeron and it made my depression worse. Wellbutrin worked but I lost a lot of weight. They're trying me on Wellbutrin again and I have to stick to a meal plan and watch my weight. My anxiety fuels my depression. I'm only 22 and I'm maxed out on Zoloft at 200mg