I recently started taking Suboxone to taper off of pain management. I am on day 6 now. Since day 2 I have had severe swelling in my calves and ankles. I have had problems with swelling previously but it is usually only a day or two and almost ALWAYS subsides at nighttime when i've laid down to rest. I wake up and the swelling is either gone or significantly improved. Well, this time it is not going away and I am getting worried. Anyone else have any problems with this? Anyone have any ideas regarding an interaction? All of the Suboxone product information is pretty vague, as in; it is a possible side-effect but not likely. Thanks in advance!