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Asthma Drug, Montelukast, Tied to Nightmares, Depression

Posted 21 Sep 2017 by Drugs.com

THURSDAY, Sept. 21, 2017 – The asthma medication Singulair (montelukast) appears linked to neuropsychiatric side effects, such as depression, aggression, nightmares and headaches, according to a new review by Dutch researchers. But experts aren't yet ready to pull the plug on this class of medication. "In our study, we give prescribing physicians the advice to be alert for signs and symptoms for allergic granulomatous angiitis [a rare complication associated with the drug] and for severe neuropsychiatric symptoms," said study lead author Dr. Meindina Haarman. "The doctor still decides whether or not to treat the patients with montelukast," said Haarman, from University Medical Center Groningen in the Netherlands. Dr. Matthew Lorber is a psychiatrist at Lenox Hill Hospital in New York City. He cautioned against discontinuing the medication in children with asthma, a lung disease that ... Read more

Related support groups: Depression, Headache, Sleep Disorders, Insomnia, Major Depressive Disorder, Asthma, Singulair, Asthma - Maintenance, Nightmares, Agitation, Agitated State, Dysthymia, Asthma - Acute, Montelukast, Night Terrors, Allergic Asthma, Zyflo, Accolate, Zyflo CR, Zafirlukast

Use of Asthma Controller Meds on the Rise Among U.S. Kids

Posted 13 Oct 2011 by Drugs.com

THURSDAY, Oct. 13 – The percentage of children with asthma in the United States who use a prescription "controller" medicine has nearly doubled since the late 1990s, a new federal government report finds. The analysis of data from the Medical Expenditure Panel Survey showed that the use of controller drugs by these children increased from 29 percent in 1997-1998 to 58 percent in 2007-2008, according to the latest News and Numbers from the U.S. Agency for Healthcare Research and Quality. Asthma controller drugs include: corticosteroids, which control inflammation and reduce the risk of airway spasms; beta-2-agonists, which make breathing easier; and leukotrienes, which help prevent asthma symptoms from occurring. Use of inhaled corticosteroids among American children with asthma increased from 15.5 percent to 40 percent, use of leukotrienes rose from 3 percent to 34 percent, and use of ... Read more

Related support groups: Asthma, Albuterol, Singulair, Asthma - Maintenance, Triamcinolone, Ventolin, Fluticasone, Qvar, Montelukast, Budesonide, Flovent, Epinephrine, Xopenex, Entocort, ProAir HFA, Mometasone, EpiPen, Proventil, Entocort EC, Salmeterol

Asthma Pills Work as Well as Inhaled Steroids: Study

Posted 4 May 2011 by Drugs.com

WEDNESDAY, May 4 – In a study that compared asthma pills against commonly prescribed inhaled steroids, British researchers found that the oral medications were as effective as the inhaled drugs. The oral medications, known as leukotriene-receptor antagonists, "have shown similar efficacy and cost and better compliance, and should be considered for any patient, not as a last option but as an option for any patient," said study co-author Dr. Stanley Musgrove, a senior research associate at the University of East Anglia in Norwich. "Every different patient will have their own issues that are important to their care: their compliance to different medications, how well they feel that different medications work for them, their concerns about different medications, any possible minor side effects, etcetera, and all of those should be considered when the clinician and the patient are making a ... Read more

Related support groups: Asthma, Singulair, Triamcinolone, Fluticasone, Qvar, Montelukast, Budesonide, Flovent, Entocort, Mometasone, Entocort EC, Pulmicort Flexhaler, Beclomethasone, Alvesco, Asmanex Twisthaler, Pulmicort Turbuhaler, Kenalog-10, Aristocort, Zyflo, Kenalog-40

FDA Finds No Link So Far Between Asthma Drugs and Suicide Risk

Posted 14 Jan 2009 by Drugs.com

WEDNESDAY, Jan. 14 – An ongoing U.S. Food and Drug Administration safety review of possible suicidal behavior among those taking asthma drugs has found no evidence of a link so far, agency officials said Tuesday. The FDA, which began the review in March 2008, said clinical trial data submitted by the manufacturers of Singulair, Accolate and Zyflo suggest the products are not associated with an increased risk of mood changes or suicidal behavior. But, the agency also noted that the trials were not designed to examine such behavior, and that the safety review will continue, probably for several more months. "We have finished our analyses of all the data the companies submitted," FDA spokeswoman Karen Riley told the Associated Press. "But that doesn't mean we have closed the book on suicidality." According to Bloomberg News, Merck & Co submitted results from 41 placebo-controlled trials ... Read more

Related support groups: Singulair, Zyflo, Accolate, Zyflo CR

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