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The Seizure Drug Zonisamide May Help Ease Symptoms of Lewy Body Dementia

Posted 25 Jan 2018 by Drugs.com

WEDNESDAY, Jan. 24, 2018 – A drug normally used to treat seizures may help ease some symptoms that occur with a type of dementia known as Lewy body dementia, researchers are reporting. The drug is called zonisamide (Zonegran). When added to treatment with the drug levodopa, zonisamide helped to control Parkinson's disease-like movement symptoms that are associated with Lewy body dementia. These ...

Pot Compound Alters Levels of Seizure Drug in Epilepsy Patients

Posted 11 Aug 2017 by Drugs.com

FRIDAY, Aug. 11, 2017 – Scientists experimenting with the marijuana compound cannabidiol as an epilepsy treatment must evaluate any interactions with other anti-seizure drugs patients are taking, researchers report. The new research from the University of Alabama at Birmingham suggests cannabidiol affects blood levels of several anti-seizure drugs, especially clobazam. Cannabidiol (CBD) has ...

Number of Americans With Epilepsy at Record Level

Posted 10 Aug 2017 by Drugs.com

THURSDAY, Aug. 10, 2017 – More Americans than ever are living with epilepsy, federal health officials reported Thursday. According to the new report, 1.2 percent of the population – about 3 million adults and 470,000 children – were being treated for epilepsy or had experienced recent seizures in 2015, the researchers from the U.S. Centers for Disease Control and Prevention said. The number of ...

Seizure Control Key to Avoiding Sudden Death With Epilepsy

Posted 25 Apr 2017 by Drugs.com

TUESDAY, April 25, 2017 – In rare cases, seizures that cause convulsions and a loss of consciousness can raise the odds of sudden death in people with epilepsy, neurologists warn. These attacks are known as generalized tonic-clonic seizures, according to a new guideline from the American Academy of Neurology (AAN) and the American Epilepsy Society. Just how rare is sudden death linked to these ...

Epilepsy Drugs in Pregnancy May Affect Infants' Fine Motor Skills

Posted 25 Sep 2013 by Drugs.com

WEDNESDAY, Sept. 25 – Young children exposed to epilepsy drugs in the womb are at increased risk of having impaired fine motor skills, according to a new study. Exposure to the drugs in breast milk, however, does not appear to pose a threat. Researchers looked at data collected from Norwegian mothers about their children's language, behavior, and motor and social skills at the ages of 6 months, ...

Epilepsy Drug Shows Promise as Weight-Loss Aid, Study Says

Posted 15 Oct 2012 by Drugs.com

MONDAY, Oct. 15 – A prescription medication originally developed to treat epilepsy may help obese adults shed weight when combined with routine nutritional counseling, researchers say. Patients who took 400 milligrams of the anti-seizure drug zonisamide daily for a year lost nearly 7.5 pounds more on average than those assigned to dietary and lifestyle changes alone, the new study found. But ...

Prescription Meds Can Put on Unwanted Pounds

Posted 2 Mar 2012 by Drugs.com

FRIDAY, March 2 – Medications taken by millions of Americans for mood disorders, high blood pressure, diabetes and other chronic conditions can have an unhealthy side effect: weight gain. While other choices exist for some types of drugs, adjusting medications is not simply a matter of switching, said Ryan Roux, chief pharmacy officer with the Harris County Hospital District, in Houston. In the ...

Epilepsy Drugs Don't Raise Suicide Risk, Study Shows

Posted 5 Aug 2010 by Drugs.com

WEDNESDAY, Aug. 4 – In 2008, the U.S. Food and Drug Administration required epilepsy medications to bear a warning label about an increased risk of suicidal behaviors. The move came after an agency review of 199 studies that found patients taking the drugs showed about twice the risk of suicidal behavior. But now a study of more than 5 million patients contradicts the FDA's findings. It suggests ...

FDA Medwatch Alert: Zonegran (zonisamide)

Posted 15 Jul 2002 by Drugs.com

FDA and Elan Pharmaceuticals added a bolded WARNING to inform healthcare professionals that pediatric patients appear to be at an increased risk for zonisamide-associated oligohidrosis and hyperthermia. Patients, especially pediatric patients, treated with Zonegran should be monitored closely for evidence of decreased sweating and increased body temperature, especially in warm or hot weather. The ...

FDA Medwatch Alert: Zonisamide (marketed as Zonegran, and generics)

Posted 23 Feb 2009 by Drugs.com

[Posted 02/23/2009] FDA notified healthcare professionals that updated clinical data has determined that treatment with zonisamide, indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy, can cause metabolic acidosis in some patients. Patients with predisposing conditions or therapies may be at greater risk for developing metabolic acidosis and the risk of ...

FDA Medwatch Alert: Antiepileptic Drugs

Posted 5 May 2009 by Drugs.com

[UPDATE 05/05/2009] FDA notified healthcare professionals that it approved updated labeling for antiepileptic drugs used to treat epilepsy, psychiatric disorders, and other conditions (e.g., migraine and neuropathic pain syndromes). FDA also required development of a medication guide, to be issued to patients each time the product is dispensed. Since issuing safety alerts on December 16, 2008 and ...

FDA Adds Suicide Warning to Epilepsy Drugs

Posted 16 Dec 2008 by Drugs.com

TUESDAY, Dec. 16 – The U.S. Food and Drug Administration announced Tuesday that it was adding a label warning on heightened suicide risk for users of antiepileptic drugs. The move, which follows the advice last summer of an FDA advisory panel, stops short of slapping the strongest "black box" warning on this class of drugs, which includes widely used medications such as clonazepam (Klonopin), ...

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Migraine Prevention, Migraine Prophylaxis, Seizures, Parkinsonian Tremor, Benign Essential Tremor

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