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Powerful Drug for Advanced Cancers May Need Less Frequent Dosing

Posted 4 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 4, 2017 – Use of a bone cancer drug once every three months, instead of monthly, does not boost the risk of bone problems over two years, a new study finds. That could reduce side effects from the drug, known as zoledronic acid (Zometa), and increase cost savings, the researchers said. The drug is used to treat the spread of breast cancer, prostate cancer and multiple myeloma to ...

Growth Hormone May Lower Odds of Fractures in Older Women

Posted 27 Aug 2015 by Drugs.com

THURSDAY, Aug. 27, 2015 – Older women with osteoporosis could get lasting benefits from a few years on growth hormone, a new, small trial suggests. Researchers found that when women with the bone-thinning disease took growth hormone for three years, their fracture risk was still reduced seven years later. Before entering the study, 56 percent of the women had suffered a bone break; over the ...

Certain Generic Meds May Help Older Patients With Early Breast Cancer

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – There's more evidence that two classes of inexpensive generic drugs reduce the risk of death in postmenopausal women with early breast cancer, a pair of new British studies find. The two classes of drugs – called aromatase inhibitors and bisphosphonates – can also be used together to increase the benefits and reduce some side effects, according to the authors of the ...

Strong Bones After 50? Women May Not Need Next Test Until 65

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – A postmenopausal woman who is 50 and still shows "normal" readings on her bone density test may not need her next such test for 10 or even 15 years, a new study finds. However, researchers led by Dr. Margaret Gourlay of the University of North Carolina at Chapel Hill stressed that younger women who do show signs of bone loss are at high risk for a major fracture, and do ...

Too Many Women Who Need Bone Screening Aren't Getting It

Posted 25 May 2015 by Drugs.com

MONDAY, May 25, 2015 – Too few women at high risk for osteoporosis are being tested for the bone-depleting condition, while too many women at low-risk are being screened, a new study suggests. A team led by Dr. Anna Lee Amarnath of the University of California, Davis, examined the medical records of nearly 51,000 women, aged 40 to 85, living in the Sacramento area. The researchers looked at ...

Early Chemo May Boost Survival in Advanced Prostate Cancer

Posted 14 May 2015 by Drugs.com

THURSDAY, May 14, 2015 – Starting the chemotherapy drug docetaxel at the same time as hormone therapy can improve survival for men with newly diagnosed, advanced prostate cancer, British researchers say. Currently, chemotherapy is generally given after hormone therapy stops working. But the new study found that when the two therapies were paired at the start of treatment, patients lived an ...

Bone Drugs May Protect Against Endometrial Cancer

Posted 22 Dec 2014 by Drugs.com

MONDAY, Dec. 22, 2014 – Bisphosphonates, which are drugs that treat bone loss, may lower the risk of endometrial cancer, new research suggests. The study found that women taking the drugs had about half the risk of endometrial cancer compared to women who don't take the drugs. Endometrial cancer – one of the most common types of cancer in women – affects the lining of the uterus. ...

Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study

Posted 3 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Many men on hormone therapy for prostate cancer aren't getting bone-strengthening drugs they may need, new Canadian research contends. Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. But one consequence of the treatment is weakening of the bones, which can lead to fractures. To reduce this risk, men can be given oral ...

Osteoporosis Drugs Work, But Review Finds No Clear Winner

Posted 8 Sep 2014 by Drugs.com

MONDAY, Sept. 8, 2014 – Many osteoporosis drugs cut women's risk of suffering a bone fracture, though it's not clear whether any one medication works better than others, a new research review finds. Reporting Sept. 8 in Annals of Internal Medicine, researchers said that for women with the bone-thinning disease osteoporosis, various drugs cut the risk of a spine fracture by 40 to 60 percent, ...

More Evidence Ties Some Bone-Building Drugs to Rare Fractures

Posted 4 Sep 2014 by Drugs.com

THURSDAY, Sept. 4, 2014 – Taking osteoporosis drugs called bisphosphonates to help prevent fractures may carry a slight risk for unusual breaks in the thigh bone, Swedish researchers report. For those who took bisphosphonates for four to five years, the so-called "relative risk" was 100 times higher than among people who didn't use the medications. But the researchers explained that the absolute ...

Bone Drugs Don't Lower Breast Cancer Risk After All, Study Finds

Posted 11 Aug 2014 by Drugs.com

MONDAY, Aug. 11 – Drugs known as bisphosphonates, commonly prescribed to treat the bone-weakening disease osteoporosis, don't appear to reduce the risk of breast cancer as previously thought, new research finds. "We found that postmenopausal women who took a bisphosphonate for three or four years did not have a decreased risk in breast cancer," said study author Trisha Hue, an epidemiologist at ...

Dr. Reddy's Announces the Launch of Zoledronic Acid Injection

Posted 6 Mar 2013 by Drugs.com

HYDERABAD, India--(BUSINESS WIRE)--Mar 5, 2013 - Dr. Reddy's Laboratories (NYSE: RDY) announced today that it has launched Zoledronic Acid Injection (4 mg/5 mL), a bioequivalent generic version of Zometa® (zoledronic acid) 4 mg/5 mL Injection in the US market on March 4, 2013, following the approval by the United States Food & Drug Administration (USFDA) of Dr. Reddy's ANDA for Zoledronic Acid ...

Men May Benefit From Osteoporosis Drug, Too: Study

Posted 31 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 31 – Older men at risk for fractures from osteoporosis may reap the same benefit as women from bone-strengthening drugs called bisphosphonates, a new study suggests. In this case, one such drug called zoledronic acid (Reclast) significantly reduced backbone breaks in men suffering from osteoporosis. Bisphosphonates work by building bone mass, the researchers explained. Age-linked ...

Newer Bone Drug Better for Advanced Breast Cancer Patients: Study

Posted 14 Aug 2012 by Drugs.com

TUESDAY, Aug. 14 – The relatively new drug denosumab (Xgeva) reduces bone complications of advanced breast cancer more effectively than another osteoporosis drug, zoledronic acid (Zometa), according to new research. Zoledronic acid belongs to a class of drugs known as bisphosphonates, which help delay bone complications such as fractures, spinal cord compression and bone pain. But zoledronic ...

More Research Points to Long-Term Ills With Bone Drugs

Posted 21 May 2012 by Drugs.com

MONDAY, May 21 – Adding more weight to concerns about possible long-term dangers of osteoporosis drugs, a new study finds that people who take the drugs, known as bisphosphonates, may be at increased risk for atypical fractures of the thigh bone (femur). Osteoporosis is a bone-thinning disease that is common in older women. An atypical femoral fracture is an unusual type of break that often ...

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Osteoporosis, Osteolytic Bone Lesions of Multiple Myeloma, Paget's Disease, Osteolytic Bone Metastases of Solid Tumors, Hypercalcemia of Malignancy

Zometa Patient Information at Drugs.com