Skip to Content

Join the 'Xuriden' group to help and get support from people like you.

Xuriden News

FDA Approves Xuriden (uridine triacetate) to Treat Hereditary Orotic Aciduria

Posted 8 Sep 2015 by Drugs.com

September 4, 2015 – Today, the U.S. Food and Drug Administration approved Xuriden (uridine triacetate), the first FDA-approved treatment for patients with hereditary orotic aciduria. Hereditary orotic aciduria is a rare metabolic disorder, which has been reported in approximately 20 patients worldwide. Hereditary orotic aciduria is inherited from a recessive gene. The disease is due to a defective or deficient enzyme, which results in the body being unable to normally synthesize uridine, a necessary component of ribonucleic acid (RNA). Signs and symptoms of the disease include blood abnormalities (anemia, decreased white blood cell count, decreased neutrophil count), urinary tract obstruction due to the formation of orotic acid crystals in the urinary tract, failure to thrive, and developmental delays. “Today’s approval and rare pediatric disease priority review voucher underscore the ... Read more

Related support groups: Hereditary Orotic Aciduria, Uridine, Xuriden

Ask a Question

Further Information

Related Condition Support Groups

Hereditary Orotic Aciduria

Xuriden Patient Information at Drugs.com