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Experimental Shingles Vaccine Looks Quite Effective: Study

Posted 15 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 14, 2016 – An experimental vaccine against shingles may offer lasting protection for most older adults who receive it, a new clinical trial found. Shingles is a painful rash that's triggered by a reactivation of the virus that causes chickenpox. About one-third of Americans develop the disease at some point, according to the U.S. Centers for Disease Control and Prevention (CDC). There already is a vaccine against shingles, but its effectiveness is limited. The new study found that the experimental vaccine protected about 90 percent of adults age 70 and up. And the effects were still apparent four years later. By comparison, the existing vaccine, Zostavax, cuts the risk of shingles by about half. And immunity wanes within five years, according to the CDC. The study results were published in the Sept. 15 issue of the New England Journal of Medicine. Researchers called ... Read more

Related support groups: Herpes Zoster, Zostavax, Varicella-Zoster, Zoster Vaccine Live, Vaccination and Prophlaxis, Varicella-Zoster - Prophylaxis, Herpes Zoster - Prophylaxis

Chickenpox Cases Down 85 Percent Since 2-Dose Vaccine Started: CDC

Posted 1 Sep 2016 by Drugs.com

THURSDAY, Sept. 1, 2016 – Chickenpox – which is caused by the varicella-zoster virus – has continued declining in the United States since 2006, when doctors began routinely recommending a second dose of chickenpox (varicella) vaccine, U.S. health officials said Thursday. States reporting vaccination data noted an 85 percent drop in the highly contagious disease between 2005-2006 and 2013-2014, according to a report from the U.S. Centers for Disease Control and Prevention. The fall-off was greatest among kids aged 5 to 14, health officials said. This is also the age group most likely to have received the second dose of varicella vaccine. Symptoms of chickenpox include an itchy, blistery rash, tiredness and fever. It tends to be more serious in babies, adults and people with a weakened immune system, the CDC noted. Before vaccination, chickenpox was commonplace, with 4 million ... Read more

Related support groups: Varicella-Zoster, Varicella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, ProQuad, Vaccination and Prophlaxis, Varicella Zoster Immune Globulin, Varizig, Varivax, Varicella-Zoster - Prophylaxis

Experimental Drug for Rheumatoid Arthritis Shows Promise

Posted 31 Mar 2016 by Drugs.com

THURSDAY, March 31, 2016 – An experimental drug to treat rheumatoid arthritis showed promise in a new six-month trial. Baricitinib substantially reduced symptoms and improved daily physical functioning among people who failed other treatments for the autoimmune disease, researchers found. "If you have active disease and you've failed existing treatment options, you should have hope," said lead researcher Dr. Mark Genovese. He is a professor of immunology and rheumatology at Stanford University School of Medicine in California. "There is another therapy, which will hopefully become available, that has demonstrated it can work in that situation." The report was published March 31 in the New England Journal of Medicine. The trial was sponsored by Eli Lilly and Co., the manufacturer of baricitinib. Lilly is currently seeking approval of the drug from the U.S. Food and Drug Administration. ... Read more

Related support groups: Rheumatoid Arthritis, High Cholesterol, Varicella-Zoster, Varicella-Zoster - Prophylaxis

Two-Dose Chickenpox Shot Gets the Job Done, Study Shows

Posted 14 Mar 2016 by Drugs.com

MONDAY, March 14, 2016 – Among school children, two doses of the chickenpox vaccine is better than one, a new study finds. Giving the first dose at age 1 and the second dose at ages 4 to 6 is nearly 100 percent effective in preventing the once common childhood disease, researchers have found. "A second dose of varicella [chickenpox] vaccine provides school-aged children with better protection against the chickenpox virus, compared to one dose alone or no vaccination," said lead researcher Dana Perella, of the Philadelphia Department of Public Health. Two doses of the vaccine protected against the moderate to severe chickenpox infections that can lead to complications and hospitalizations, she said. The report was published online March 14 and will appear in the April print issue of the journal Pediatrics. Chickenpox is a viral infection that causes a painful, itchy rash with small, ... Read more

Related support groups: Varicella-Zoster, Varicella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, ProQuad, Vaccination and Prophlaxis, Varivax, Varicella-Zoster - Prophylaxis

Health Tip: Chickenpox Can Be Dangerous

Posted 5 Feb 2016 by Drugs.com

-- Chickenpox is notoriously contagious, and for some people it can be very dangerous. Women who are pregnant, young children, the elderly and people with a weakened immune system are at greatest risk of complications. The U.S. Centers for Disease Control and Prevention mentions these potential complications of chickenpox: Pneumonia, blood poisoning or dehydration. Brain inflammation or infection. Bacterial infection affecting the skin or soft tissues, especially among children. Infection of the joints or bones. Toxic shock syndrome. Unusual bleeding. Read more

Related support groups: Varicella-Zoster, Varicella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, ProQuad, Vaccination and Prophlaxis, Varivax, Varicella-Zoster - Prophylaxis

Chickenpox, Shingles Vaccines Linked to Rare Eye Inflammation

Posted 25 Jan 2016 by Drugs.com

MONDAY, Jan. 25, 2016 – The vaccine for chickenpox and shingles has been linked to inflammation of the eye's cornea, but the number of such cases is small, a new study says. "Keratitis, or inflammation of the clear layer on the front of the eye, is a vision issue that can cause serious complications or even permanent damage to your vision if left untreated," Dr. Frederick Fraunfelder, chair of the ophthalmology department and director of the University of Missouri Eye Institute, said in a university news release. Researchers found 20 cases of keratitis in children and adults that occurred within a month of receiving a chickenpox or shingles vaccine. Symptoms of the disorder developed within 24 days of vaccination among adults. In children, symptoms began within 14 days of vaccination, the researchers said. The researchers said there is a probable relationship between the vaccine and ... Read more

Related support groups: Eye Conditions, Herpes Zoster, Zostavax, Varicella-Zoster, Keratitis, Corneal Ulcer, Eye Redness/Itching, Corneal Abrasion, Varicella Virus Vaccine, Herpes Zoster Iridocyclitis, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Vaccination and Prophlaxis, Zoster Vaccine Live, Visual Defect/Disturbance, ProQuad, Varivax, Varicella-Zoster - Prophylaxis

Health Tip: Coping With Chickenpox

Posted 24 Aug 2015 by Drugs.com

-- What can you do if you get chickenpox – besides scratch? The American Academy of Family Physicians suggests: Keep the room cool, as heat can make itchy skin worse. Put a cool, damp compress on the itchiest spots. Keep fingernails trimmed short so you don't break the skin if you do scratch. Soak in a lukewarm oatmeal bath. Apply calamine lotion. Read more

Related support groups: Skin Rash, Benadryl, Promethazine, Hydroxyzine, Zyrtec, Claritin, Allegra, Phenergan, Loratadine, Vistaril, Diphenhydramine, Cetirizine, Atarax, Cyproheptadine, Fexofenadine, Periactin, Chlorpheniramine, Xyzal, Levocetirizine, Benadryl Allergy

Vaccine Sharply Curbs Chickenpox Cases in U.S.

Posted 13 Aug 2015 by Drugs.com

THURSDAY, Aug. 13, 2015 – Chickenpox cases in the United States have dropped sharply since a vaccine against the disease became available in 1995, a new study shows. Also, hospitalizations and outpatient visits for chickenpox have continued to fall since 2006, when a second dose of the vaccine was recommended to boost protection against the disease, the researchers found. Before 1995, about 4 million people in the United States got chickenpox each year, nearly 11,000 were hospitalized, and up to 150 died of the disease, according to the U.S. Centers for Disease Control and Prevention. For this study, CDC researchers analyzed national health insurance claims data. They found there were 93 percent fewer hospitalizations for chickenpox in 2012, and 84 percent fewer outpatient visits for the disease than in the period before the vaccine was introduced. After the second dose recommendation ... Read more

Related support groups: Varicella-Zoster, Vaccination and Prophlaxis, Varicella-Zoster - Prophylaxis

Shingles Vaccine Appears to Cut Odds of Long-Term Pain

Posted 4 Jun 2015 by Drugs.com

TBD, 2015 – Even when shingles vaccination does not prevent the disease, it reduces the risk of long-term pain that can occur as a complication of the condition, according to a new study. Although the U.S. Advisory Council on Immunization Practices recommends shingles vaccination for people 60 and older, vaccination rates remain low, the researchers say. "Hopefully, this study will encourage more people to get vaccinated in order to reduce the long-term pain and potential disability associated with shingles," said lead author Hung Fu Tseng, a researcher with Kaiser Permanente Southern California. Tseng's team analyzed the medical records of 2,400 people in Southern California over age 60 who developed shingles. Some had been vaccinated against the disease. Among vaccinated patients, just over 4 percent of women and 6 percent of men developed long-term pain (post-herpetic neuralgia, or ... Read more

Related support groups: Persisting Pain, Shingles, Postherpetic Neuralgia, Varicella-Zoster, Varicella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, ProQuad, Varivax, Varicella-Zoster - Prophylaxis

Anti-Vaccine Parents Cluster in Rich, White Areas

Posted 3 Jun 2015 by Drugs.com

WEDNESDAY, June 3, 2015 – Parents who cite "personal beliefs" to get their children exempted from routine vaccinations are typically white and well-to-do – at least in California, a new study finds. The results, published June 1 in Pediatrics, confirm what other studies have suggested: Anti-vaccine sentiment in the United States appears strongest among wealthier white families. But the study also found another pattern that surprised experts: California schools with high rates of personal-belief exemptions often had high rates of exemptions for medical reasons, too. "There's no clear explanation for why that would be," said Dr. Paul Offit, chief of infectious diseases at Children's Hospital of Philadelphia, who was not involved in the study. But the concern, he added, is that some children exempted for medical reasons could be put at risk if their classmates are not vaccinated against ... Read more

Related support groups: BCG, Zostavax, Yellow Fever Vaccine, Gardasil, Prevnar 13, Prevnar, Measles, Tetanus Toxoid, Vivotif Berna, Rabies Vaccine, Human Diploid Cell, FluLaval, Typhoid Vaccine, Live, Hepatitis B Adult Vaccine, Twinrix, Vivotif Berna Vaccine, Pneumococcal 23-polyvalent Vaccine, Varicella Virus Vaccine, Cervarix, Smallpox Vaccine, Provenge

Most States Not Ready to Handle Infectious Disease Outbreaks: Report

Posted 19 Dec 2014 by Drugs.com

THURSDAY, Dec. 18, 2014 – Ebola's entrance into the United States – along with Angelina Jolie's chickenpox and the National Hockey League's mumps outbreak – have highlighted cracks in the nation's public health defense against infectious disease, according to a new health policy report released Thursday. Half of U.S. states are poorly prepared to prevent, detect and respond to infectious disease outbreaks. That was the main conclusion of the report issued jointly by the Trust for America's Health and the Robert Wood Johnson Foundation. "Ebola has served as a major wake-up call to the United States," said Jeffrey Levi, executive director of the Trust for America's Health. "It's a reminder that an infectious disease anywhere is a threat everywhere, and Ebola has raised attention to serious gaps in our ability to manage disease outbreaks and contain their spread. It was very disturbing ... Read more

Related support groups: Varicella-Zoster, Varicella-Zoster - Prophylaxis, Mumps Prophylaxis

Combo Vaccine Raises Risk of Fever-Related Seizures in Toddlers: Study

Posted 9 Jun 2014 by Drugs.com

MONDAY, June 9, 2014 – Toddlers who get a newer vaccine that fights four infections in one jab have a slightly increased risk of fever-induced seizure, a large new study confirms. At issue is a vaccine that targets measles, mumps, rubella and varicella (chickenpox) in one shot, instead of giving the traditional MMR and varicella vaccines separately. In theory, one shot sounds better than two. But in the new study, 1-year-olds who received Priorix-Tetra – the MMRV vaccine used in Canada – were twice as likely to develop a fever-related seizure as children who got separate MMR and chickenpox shots. The findings are in line with a 2010 study of the MMRV vaccine used in the United States, known as ProQuad. In the United States, parents now have to explicitly ask for the MMRV if they want their toddler to have it, said Dr. Nicola Klein, who led the ProQuad study. But even with the ... Read more

Related support groups: Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Vaccination and Prophlaxis, ProQuad, Rubella Prophylaxis, Varicella-Zoster - Prophylaxis, Mumps Prophylaxis, Measles Prophylaxis

Boomers Should Consider Shingles Vaccine, Physician Says

Posted 5 Mar 2014 by Drugs.com

WEDNESDAY, March 5, 2014 – People older than 50 can reduce their risk for developing shingles by being vaccinated against the varicella-zoster virus that causes the painful condition, an expert says. "People who have had shingles previously can still receive the vaccine called Zostavax. If you are above the age of 50 years old, you should talk to your health care provider about the shingles vaccines," advised Dr. Khalilah Babino, immediate care physician at Loyola University Health System. Shingles is caused by the same virus responsible for chicken pox. Most people who get shingles are older than 50 because the virus can remain dormant in the body for years before being activated again, according to background information in a university news release. People at particularly high risk for developing shingles include those who've had chicken pox and those with cancer, autoimmune ... Read more

Related support groups: Zostavax, Varicella Virus Vaccine, Zoster Vaccine Live, Varivax, Varicella-Zoster - Prophylaxis

Second Dose of Vaccine Cuts Chickenpox Cases Even More, Study Finds

Posted 8 Oct 2013 by Drugs.com

TUESDAY, Oct. 8 – Two doses of chickenpox vaccine are better than one, new research confirms. After the introduction of the second dose of chickenpox vaccine, the rates of chickenpox infection dropped 76 percent and 67 percent at two U.S. sites tracked for the study on opposite sides of the country. Rates of infection in adults and infants – two groups who generally don't receive the vaccine – also went down, suggesting that higher levels of immunity in the population are decreasing the amount of circulating chickenpox. "The first dose of vaccine was highly protective for reducing hospitalizations, deaths and other severe complications, but it wasn't fully protective against mild disease. There were still mild breakthrough cases, and these people could transmit the disease to those who hadn't been vaccinated," said Dr. Rachel Civen, senior study author and a medical epidemiologist ... Read more

Related support groups: Varicella Virus Vaccine, Varicella-Zoster - Prophylaxis, Varivax

Teen's Death From Chickenpox Highlights Need for Vaccination, CDC Reports

Posted 11 Apr 2013 by Drugs.com

THURSDAY, April 11 – The death from chickenpox of an otherwise healthy 15-year-old Ohio girl should remind parents of the importance of vaccination against the disease, U.S. health officials reported Thursday. The teenager was admitted to the hospital with severe chickenpox, also known as varicella, and died three weeks later because of serious complications, according to a case study provided by the U.S. Centers for Disease Control and Prevention. "Varicella can be deadly, even in seemingly normal individuals," said Dr. Kenneth Bromberg, director of the Vaccine Research Center and chairman of pediatrics at the Brooklyn Hospital Center in New York City. "It is likely that death would have been prevented with prior vaccination," he said. Chickenpox, which is highly contagious, is usually a mild illness characterized by an uncomfortable, itchy rash. But it sometimes leads to serious ... Read more

Related support groups: Varicella-Zoster, Varicella Virus Vaccine, Varicella-Zoster - Prophylaxis, Varivax

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