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FDA Approves Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol) for the Treatment of COPD

Posted 19 Sep 2017 by Drugs.com

London UK – 18 September 2017 – GlaxoSmithKline plc (LSE/NYSE: GSK) and Innoviva, Inc. (NASDAQ: INVA) today announced that the US Food and Drug Administration (FDA) has approved once-daily, single inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI), under the brand name Trelegy Ellipta, for the long-term, once-daily, maintenance treatment of patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema, who are on a fixed-dose combination of fluticasone furoate and vilanterol for airflow obstruction and reducing exacerbations in whom additional treatment of airflow obstruction is desired or for patients who are already receiving umeclidinium and a fixed-dose combination of fluticasone furoate and vilanterol. Trelegy Ellipta is not indicated for relief of acute bronchospasm or the treatment of asthma. Trelegy E ... Read more

Related support groups: Chronic Obstructive Pulmonary Disease, Bronchitis, Chronic Obstructive Pulmonary Disease, Maintenance, Fluticasone, Breo Ellipta, Chronic Obstructive Pulmonary Disease, Acute, Anoro Ellipta, Arnuity Ellipta, Umeclidinium, Umeclidinium/vilanterol, Incruse Ellipta, Trelegy Ellipta, Fluticasone/umeclidinium/vilanterol, Fluticasone/vilanterol

Obesity May Raise Girls' Risk of Asthma, Allergies

Posted 6 Mar 2017 by Drugs.com

MONDAY, March 6, 2017 – Obese girls may face a significantly higher risk for developing allergies, a new study suggests. But the researchers found the opposite was true for obese boys: They may actually face a slightly diminished risk for asthma, food allergies and eczema when compared to normal-weight boys. "We found a direct increase in the number of atopic [allergic] diseases associated with obesity in urban female children and teenagers, but not in males," said study co-author Dr. Sairaman Nagarajan. He's a resident physician in the department of pediatrics at SUNY Downstate Medical Center in New York City. "These results were highly significant, even after adjusting for the effects of age and race," he said. Nagarajan and his colleagues were scheduled to present their findings Monday at the annual meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI), in Atlanta. ... Read more

Related support groups: Obesity, Asthma, Weight Loss, Asthma - Maintenance, Spiriva, Fluticasone, Qvar, Budesonide, Asthma - Acute, Flovent, Entocort, Ipratropium, Entocort EC, Mometasone, Atrovent, Spiriva HandiHaler, Beclomethasone, Tiotropium, Uceris, Alvesco

Mice May Be Key to Kids' Asthma Attacks at School

Posted 2 Dec 2016 by Drugs.com

FRIDAY, Dec. 2, 2016 – Research investigating schoolchildren's asthma attacks has pointed to a tiny foe: mice. Allergens from the rodents can infiltrate the air, the study found, and may be a major cause of asthma attacks in the school environment. It's known that many different allergy triggers – from dust mites to mold to pet dander – can fuel children's asthma symptoms. But most research has focused on the triggers in kids' homes. "In this study, we've identified the school as an important factor, too," said researcher Dr. Wanda Phipatanakul, an allergy specialist at Boston Children's Hospital. That said, she stressed, the findings do not actually prove that schools' rodent problems were the cause of kids' symptoms. The next step, Phipatanakul said, is a study where schools will get air purifiers and "integrated pest management," to see if that improves students' respiratory ... Read more

Related support groups: Asthma, Asthma - Maintenance, Symbicort, Spiriva, Advair HFA, Advair Diskus, Fluticasone, Qvar, Budesonide, Asthma - Acute, Flovent, Breo Ellipta, Entocort, Dulera, Combivent, Bronchial, Ipratropium, Entocort EC, Mometasone, Atrovent

COPD Deaths Down for Most Americans: CDC

Posted 8 Sep 2016 by Drugs.com

THURSDAY, Sept. 8, 2016 – Fewer Americans are dying from chronic obstructive pulmonary disease (COPD), but not black women and the middle-aged, a new government report shows. Between 2000 and 2014, there was a 12 percent overall drop in deaths from the progressive lung disease, according to the U.S. Centers for Disease Control and Prevention. Report co-author Hanyu Ni said the figures aren't unexpected, noting that "the declines in the COPD-related mortality are consistent with declines in the prevalence of current smoking for men and women in the United States." But, Ni added, the study only quantified death rate trends, and didn't look at the reasons behind those trends. Ni is an associate director for science with the CDC's division of vital statistics at the U.S. National Center for Health Statistics. Dr. David Mannino, who's with the University of Kentucky's College of Public ... Read more

Related support groups: Chronic Obstructive Pulmonary Disease, Spiriva, Albuterol, Chronic Obstructive Pulmonary Disease, Maintenance, Ventolin, Fluticasone, Ribavirin, Qvar, Budesonide, Flovent, Epinephrine, Entocort, ProAir HFA, Xopenex, Ipratropium, Tobramycin, Chronic Obstructive Pulmonary Disease, Acute, Entocort EC, EpiPen, Mometasone

Secondhand Smoke May Double Risk of Hospitalization for Kids With Asthma

Posted 24 Sep 2015 by Drugs.com

THURSDAY, Sept. 24, 2015 – Exposure to secondhand smoke puts children with asthma at nearly double the risk of winding up in the hospital, a new analysis reveals. For these kids, secondhand smoke can worsen symptoms and make their condition more difficult to control. So parents need to be aware of these additional risks, the researchers warned. "Previous studies have linked secondhand smoke exposure with increased asthma prevalence, poorer asthma control and increased symptoms," lead study author Zhen Wang, from the Mayo Clinic in Rochester, Minn., said in an American College of Allergy, Asthma and Immunology news release. "We wanted to quantify the strength of the association, and to show just how much greater the risk is of hospitalization for kids with asthma who are exposed to secondhand smoke in the home," Wang added. One expert said the findings make sense. "Having treated ... Read more

Related support groups: Asthma, Smoking, Asthma - Maintenance, Symbicort, Spiriva, Advair HFA, Advair Diskus, Fluticasone, Qvar, Budesonide, Asthma - Acute, Flovent, Breo Ellipta, Entocort, Dulera, Combivent, Ipratropium, Entocort EC, Mometasone, Atrovent

Asthma Treatments Fail Older Patients More Often: Study

Posted 12 Jun 2015 by Drugs.com

FRIDAY, June 12, 2015 – Asthma treatments, especially inhaled corticosteroids, are less likely to work for older patients, a new study suggests. Researchers looked at 1,200 patients with mild-to-moderate asthma, and found that treatment failure occurred in about 17 percent of those aged 30 and older, compared with about 10 percent of those younger than 30. Lower lung function and having asthma for a longer time were associated with a higher risk of treatment failure. When the researchers focused on specific therapies, they found that treatment failure increased consistently for every year above age 30 among patients who used inhaled corticosteroids. Patients aged 30 and older who used inhaled corticosteroids, either alone or in combination with other therapies, were more than twice as likely to have treatment failure than those younger than 30, the investigators found. Men and women ... Read more

Related support groups: Asthma, Asthma - Maintenance, Symbicort, Spiriva, Albuterol, Ventolin, Advair HFA, Advair Diskus, Asthma - Acute, Epinephrine, Breo Ellipta, Dulera, Combivent, ProAir HFA, Xopenex, Ipratropium, Theophylline, EpiPen, Atrovent, Adrenalin

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Chronic Obstructive Pulmonary Disease, Maintenance, Chronic Obstructive Pulmonary Disease

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Incruse Ellipta

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