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Global Efforts to Combat TB Epidemic Falling Short

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Countries around the world need to work harder to combat tuberculosis infections and deaths, a new World Health Organization report says. Nations across the globe have pledged to reduce tuberculosis (TB) infections by 80 percent and TB deaths by 90 percent by 2030, but they must work faster if they want to meet these goals, according to the WHO. "We face an uphill battle to reach the global targets for tuberculosis," WHO Director General Dr. Margaret Chan said in an organization news release. "There must be a massive scale-up of efforts, or countries will continue to run behind this deadly epidemic and these ambitious goals will be missed." Tuberculosis is a disease that mainly affects the lungs. The bacteria that cause TB are primarily spread from person to person through tiny droplets from coughs and sneezes. The global response to the TB epidemic did manage ... Read more

Related support groups: Tuberculosis, Rifampin, Tuberculosis - Latent, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Pyrazinamide, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifabutin, Rifamate, Rifater, Tuberculosis - Resistant, Mycobutin, Rifadin, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis

Drug-Resistant Germs Thrive in America's Corroding Water Systems

Posted 23 Sep 2016 by Drugs.com

FRIDAY, Sept. 23, 2016 – The thousands of miles of aging, corroding pipes that bring water to Americans each day may be home to dangerous drug-resistant bacteria, a new report warns. These harmful bacteria include legionella, which causes Legionnaires' disease; pseudomonas, which can trigger pneumonia; and mycobacteria, which can cause tuberculosis and other illnesses, the researchers said. While these bacteria thrive in many environments, they "can [also] live in the pipes; they can survive on tiny amounts of nutrients found in water," explained lead researcher Dr. Jeffrey Griffiths, a professor of public health and medicine at Tufts University School of Medicine in Boston. Overall, his team's analysis of 100 million Medicare records found that between 1991 and 2006, more than 617,000 older Americans were hospitalized after falling ill from infection with these three common bacteria ... Read more

Related support groups: Infections, Bacterial Infection, Methicillin-Resistant Staphylococcus Aureus Infection, Tuberculosis, Legionella Pneumonia

Tuberculosis Decline in U.S. Has Stalled, CDC Reports

Posted 24 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – Two decades of progress toward eliminating tuberculosis in the United States has stalled, with incidence of the lung disease holding steady from 2013 to 2015, a federal government report shows. "Resuming progress toward TB elimination in the United States will require intensification of efforts both in the U.S. and globally," said researchers from the U.S. Centers for Disease Control and Prevention's National Tuberculosis Surveillance System. If not treated, TB can be fatal. The bacterial infection is spread through the air, when someone infected coughs, sneezes or speaks. However, it is not easily transmitted – you must be in close contact with someone who has TB for a long period of time, according to the American Lung Association. Overall, TB incidence leveled off at about three new cases per 100,000 people each year between 2013 and 2015, according to ... Read more

Related support groups: Xifaxan, Tuberculosis, Rifampin, Rifaximin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifamate, Rifabutin, Rifadin, Tuberculosis - HIV Negative, Rifater, Mycobutin, Tuberculosis - Resistant, Tuberculosis - HIV Positive, Rimactane, IsonaRif

Screen High-Risk Adults for Tuberculosis, Experts Say

Posted 8 Mar 2016 by Drugs.com

TUESDAY, March 8, 2016 – Adults at greater risk for latent tuberculosis infection should be screened for the condition, the U.S. Preventive Services Task Force recommends. "The task force recommends that primary care clinicians screen adults at increased risk for [latent TB] to help prevent the progression to active TB," panel member Dr. Francisco Garcia said in a task force news release. Garcia is director and chief medical officer of the Pima County Health Department in Tucson, Ariz. Tuberculosis, commonly known as TB, is an infection caused by bacteria. Anyone in close contact with someone with tuberculosis may be exposed to the bacteria. It spreads through the air when an infected person coughs or sneezes, according to the health panel. TB usually attack the lungs, but the bacteria can attack any part of the body such as the kidney, spine and brain. If it isn't treated properly, ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - HIV Negative, Tuberculosis - Resistant, Adrenal Tuberculosis, Tuberculosis - HIV Positive

New TB Test May Help Simplify Diagnosis

Posted 20 Feb 2016 by Drugs.com

FRIDAY, Feb. 19, 2016 – A simple new blood test for tuberculosis may one day help improve diagnosis and treatment of the deadly disease in developing countries, researchers report. The inexpensive test identifies a gene expression "signature" that distinguishes people with active TB from those with either latent TB or other diseases, according to the research team from the Stanford University School of Medicine, in Palo Alto, Calif. The work is outlined in a paper published online Feb. 19 in The Lancet Respiratory Medicine journal. Each year, 9.6 million people worldwide are newly infected with TB, a bacterial infection that usually affects the lungs, and 1.5 million die from the difficult-to-diagnose disease, the researchers noted. "One-third of the world's population is currently infected with TB. Even if only 10 percent of them get active TB, that's still 3 percent of the world's ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Tuberculosis - Resistant, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis, Adrenal Tuberculosis, Tuberculosis - HIV Positive, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy, Tuberculous Esophagitis

TB Cases Falling for Foreign-Born People in U.S.

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Tuberculosis cases among foreign-born people in the United States fell by one-fifth in recent years, and the reasons for the decline depend on people's country of origin, a new study suggests. Tuberculosis (TB) is a bacterial infection affecting the lungs and sometimes other organs. Overall, TB cases in the United States decreased over the past two decades, but TB cases among foreign-born people remained higher than in the general population, the study authors said. Between 2007 and 2011, there was a 19 percent drop in TB cases among all foreign-born people in the nation, according to researchers from the U.S. Centers for Disease Control and Prevention. TB cases declined in people recently arriving from Mexico, China, India, the Philippines and Vietnam – the five countries that account for most of the foreign-born people with TB in the United States, the ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Rifamate, Rifabutin, Isoniazid/Rifampin, Rifadin, Tuberculous Meningitis, Rifater, Mycobutin, Tuberculosis - Resistant, Isoniazid/Pyrazinamide/Rifampin, Rimactane, IsonaRif, Tuberculous Pleurisy

Toxic Chemicals May Weaken Infants' Response to TB Vaccine

Posted 18 Dec 2015 by Drugs.com

FRIDAY, Dec. 18, 2015 – Exposure to toxic chemicals while in the womb or in early life may weaken a baby's immune system response to the tuberculosis (TB) vaccine, researchers say. The study focused on two common toxins: PCBs, an industrial chemical; and DDT, used in pesticides. These so-called "persistent" pollutants are not easily broken down and remain a health threat years after being banned. PCBs were banned in the United States in 1979. DDT is banned in the United States, but is still used in some countries to control malaria-carrying mosquitoes, the study authors, from the University of Rochester in New York, said in a university news release. The researchers analyzed blood samples and immune responses from 516 pairs of mothers and infants in an area of Slovakia heavily contaminated with environmental toxins. Each baby received the tuberculosis vaccine in their first four days ... Read more

Related support groups: Tuberculosis, BCG, Poisoning, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Toxic Reactions Incl Drug and Substance Abuse, Tuberculosis - Extrapulmonary, Tice BCG, Tubersol, Tuberculin Purified Protein Derivative, Aplisol, Tuberculous Meningitis, Tuberculin Tine Test, Vaccination and Prophlaxis, Tice BCG Vaccine, Tuberculosis - Resistant, Tuberculosis - Urinary Tract

More Than Half of U.S. States Not Well Prepared for Disease Outbreaks: Study

Posted 17 Dec 2015 by Drugs.com

THURSDAY, Dec. 17, 2015 – More than half of U.S. states are poorly prepared to respond to infectious disease outbreaks, a new report says. Twenty-eight states and Washington, D.C. did not pass muster for preventing, detecting, diagnosing and responding to such outbreaks, researchers found. They added that the United States must boost efforts to protect Americans from new threats such as Middle East respiratory syndrome coronavirus (MERS-CoV) and antibiotic-resistant superbugs, along with resurging diseases such as tuberculosis, whooping cough and gonorrhea. Delaware, Kentucky, Maine, New York and Virginia tied for the top score, achieving eight of 10 indicators of preparedness. They were followed by: Alaska, California, Maryland, Massachusetts, Minnesota and Nebraska at seven of 10; and Arkansas, Illinois, Iowa, New Hampshire, New Jersey, New Mexico, North Carolina, North Dakota, ... Read more

Related support groups: Influenza, Methicillin-Resistant Staphylococcus Aureus Infection, Tuberculosis, Pertussis, Gonococcal Infection, Vaccination and Prophlaxis, Middle East Respiratory Syndrome

Swiss Report Highlights Danger of Drug-Resistant Tuberculosis

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – A new report on a patient in Switzerland who nearly died after catching a highly drug-resistant strain of tuberculosis illustrates exactly what public health officials around the world fear most. Although antibiotics have largely eradicated tuberculosis in the United States in recent decades, experts say evidence is mounting that the bacteria is becoming increasingly resistant to these medications. Details of the Swiss case are reported in the Nov. 12 issue of the New England Journal of Medicine by lead investigator Sebastien Gagneux, head of tuberculosis research with the Swiss Tropical and Public Health Institute at the University of Basel, and colleagues. Normally, Gagneux said, tuberculosis patients are treated for six months with a daily drug "cocktail" comprised of four different first-line medications. The goal: to hem in tuberculosis (TB) while ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - Resistant, Tuberculous Meningitis, Adrenal Tuberculosis, Sirturo, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy, Bedaquiline, Tuberculous Esophagitis

E-Pillboxes Improve Medication Adherence, Study Finds

Posted 15 Sep 2015 by Drugs.com

TUESDAY, Sept. 15, 2015 – Electronic reminders may help people with tuberculosis take their medication properly, a new study suggests. Tuberculosis (TB) patients are less likely to miss doses when they receive alerts from an electronic pillbox, researchers report in the Sept. 15 issue of PLOS Medicine. Electronic pillboxes use visual, audio and/or vibration cues to signal when it's time to take medication. TB is a bacterial infection that mainly strikes the lungs. The traditional method of ensuring medical adherence in TB patients is to watch people take their medicine, but the study authors said this isn't doable in remote areas such as rural China. "Innovative approaches to enable patients to adhere to TB treatment are needed. Widespread use of medication monitors in national TB control programs can benefit from the development of a low-cost and reliable medication monitor as well as ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Tuberculosis - Active, Ethambutol, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Tuberculosis - Extrapulmonary, Rifamate, Isoniazid/Rifampin, Rifabutin, Rifadin, Mycobutin, Rifater, Myambutol, Nydrazid, IsonaRif, Rimactane, Priftin

U.S. Health Officials Search for Those Exposed to Drug-Resistant TB

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – U.S. health authorities are trying to find anyone who may have had contact with a woman who has been diagnosed with a highly drug-resistant form of tuberculosis. The woman flew from India to Chicago in April. She then traveled to Missouri and Tennessee before returning to Chicago, where she sought treatment at a hospital about seven weeks after arriving in the United States, The New York Times reported late Monday. At the hospital, the woman was diagnosed with extensively drug-resistant tuberculosis (XDR-TB). On Friday, she was transferred by special air and ground ambulances to a U.S. National Institutes of Health (NIH) hospital in Bethesda, Md. The woman is in an isolation room and the hospital "is providing care and treatment for the patient in connection with an existing NIH clinical protocol for treating TB, including XDR forms," the NIH said. The U.S. ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Tuberculosis - Prophylaxis, Tuberculosis - Resistant, Vaccination and Prophlaxis

New Trial Tests Whether TB Shot Fights Type 1 Diabetes

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – Researchers are launching a clinical trial to see if a vaccine approved long ago to prevent tuberculosis may also hold promise as a treatment for type 1 diabetes. The proposed five-year study is designed to investigate whether repeated injections of the tuberculosis vaccine bacille Calmette-Guerin (or BCG vaccine) can quiet the immune system attack that causes type 1 diabetes and improve blood sugar levels in people with long-standing diabetes. "BCG is showing so much promise in worldwide trials [for conditions such as multiple sclerosis]," said study author Dr. Denise Faustman, director of the immunobiology laboratory at Massachusetts General Hospital in Boston. While some may hold out hope that BCG will reverse type 1 diabetes in people, findings from Faustman's earlier – albeit smaller – human trial suggest the effects are likely to be far more subtle. "The ... Read more

Related support groups: Insulin, Multiple Sclerosis, Lantus, Diabetes, Type 1, Novolog, Humalog, Lantus Solostar, Levemir, Tuberculosis, BCG, Novolin R, Novolin N, Lantus Solostar Pen, Humulin N, Humulin R, NovoLog FlexPen, Humalog KwikPen, Tuberculosis - Active, Toujeo, Apidra

18th Century Mummies Reveal How TB Spread Through Europe

Posted 8 Apr 2015 by Drugs.com

WEDNESDAY, April 8, 2015 – Naturally mummified bodies from an 18th century crypt in Hungary provide new insight into tuberculosis infections in Europe during that time, researchers say. The discovery could also help health officials fight future tuberculosis (TB) outbreaks, the scientists suggested. Analyses of samples taken from the bodies in the crypt in the Dominican church of Vac uncovered 14 TB genomes. The research suggests that some of the victims had several strains of TB, perhaps a common occurrence when the disease was at its peak in Europe, the researchers said. "Microbiological analyses of samples from contemporary TB patients usually report a single strain of tuberculosis per patient. By contrast, five of the eight bodies in our study yielded more than one type of tuberculosis – remarkably from one individual we obtained evidence of three distinct strains," study author ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active

Decline in U.S. Tuberculosis Rates Slows: CDC

Posted 19 Mar 2015 by Drugs.com

THURSDAY, March 19, 2015 – As health officials in Kansas struggle with an outbreak of tuberculosis at a local high school, federal officials reported Thursday that the annual decline in U.S. cases is slowing. In 2014, there were slightly more than 9,400 TB cases in the United States, a rate of three cases per 100,000 people. That's about 2 percent lower than the TB rate in 2013, according to data from the U.S. Centers for Disease Control and Prevention. However, "This decline in the rate of TB was the smallest decrease in more than a decade and suggests the need for ongoing evaluation of TB elimination strategies overall and within high-risk populations," the CDC researchers wrote. According to the CDC, tuberculosis is more common in certain groups, particularly foreign-born people, who have a TB rate 13 times higher than those born in the United States. Compared to whites, the TB rate ... Read more

Related support groups: Tuberculosis, Tuberculosis - Active

New data shows test can help physicians remove patients with suspected TB from isolation earlier

Posted 12 Feb 2015 by Drugs.com

February 12, 2015 – The FDA today cleared the Cepheid Xpert MTB/RIF Assay to help physicians determine if patients with suspected tuberculosis (TB) can be removed from airborne infection isolation. This expanded use allows healthcare providers to use one or two negative Xpert MTB/RIF Assay test results to help them determine whether a patient showing signs and symptoms of pulmonary TB should continue to be kept in a hospital airborne isolation room. TB is caused by Mycobacterium tuberculosis complex (MTB-complex) and usually attacks the lungs. Many people carry the MTB-complex bacteria without ever developing active disease. Common signs and symptoms of active TB include a bad cough lasting three weeks or longer, chest pain, coughing up blood, weakness, fatigue and weight loss. Current CDC TB infection control guidelines recommend placing a patient suspected of having active TB in an ... Read more

Related support groups: Tuberculosis, Diagnosis and Investigation

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Tuberculosis - Latent, Tuberculosis - Active, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - HIV Positive, Pulmonary Tuberculosis, Tuberculosis - Resistant, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown, Bacterial Infection