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Tuberculosis - Prophylaxis News

Global Efforts to Combat TB Epidemic Falling Short

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Countries around the world need to work harder to combat tuberculosis infections and deaths, a new World Health Organization report says. Nations across the globe have pledged to reduce tuberculosis (TB) infections by 80 percent and TB deaths by 90 percent by 2030, but they must work faster if they want to meet these goals, according to the WHO. "We face an uphill battle to reach the global targets for tuberculosis," WHO Director General Dr. Margaret Chan said in an organization news release. "There must be a massive scale-up of efforts, or countries will continue to run behind this deadly epidemic and these ambitious goals will be missed." Tuberculosis is a disease that mainly affects the lungs. The bacteria that cause TB are primarily spread from person to person through tiny droplets from coughs and sneezes. The global response to the TB epidemic did manage ... Read more

Related support groups: Tuberculosis, Rifampin, Tuberculosis - Latent, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Rifamate, Isoniazid/Rifampin, Rifabutin, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis, Myambutol, Rifater, Tuberculosis - Resistant, Mycobutin, Rifadin

Tuberculosis Decline in U.S. Has Stalled, CDC Reports

Posted 24 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – Two decades of progress toward eliminating tuberculosis in the United States has stalled, with incidence of the lung disease holding steady from 2013 to 2015, a federal government report shows. "Resuming progress toward TB elimination in the United States will require intensification of efforts both in the U.S. and globally," said researchers from the U.S. Centers for Disease Control and Prevention's National Tuberculosis Surveillance System. If not treated, TB can be fatal. The bacterial infection is spread through the air, when someone infected coughs, sneezes or speaks. However, it is not easily transmitted – you must be in close contact with someone who has TB for a long period of time, according to the American Lung Association. Overall, TB incidence leveled off at about three new cases per 100,000 people each year between 2013 and 2015, according to ... Read more

Related support groups: Xifaxan, Tuberculosis, Rifampin, Rifaximin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifamate, Rifabutin, Tuberculosis - HIV Negative, Rifater, Mycobutin, Tuberculosis - Resistant, Rifadin, Rifapentine, Tuberculosis - HIV Positive, Rimactane

Screen High-Risk Adults for Tuberculosis, Experts Say

Posted 8 Mar 2016 by Drugs.com

TUESDAY, March 8, 2016 – Adults at greater risk for latent tuberculosis infection should be screened for the condition, the U.S. Preventive Services Task Force recommends. "The task force recommends that primary care clinicians screen adults at increased risk for [latent TB] to help prevent the progression to active TB," panel member Dr. Francisco Garcia said in a task force news release. Garcia is director and chief medical officer of the Pima County Health Department in Tucson, Ariz. Tuberculosis, commonly known as TB, is an infection caused by bacteria. Anyone in close contact with someone with tuberculosis may be exposed to the bacteria. It spreads through the air when an infected person coughs or sneezes, according to the health panel. TB usually attack the lungs, but the bacteria can attack any part of the body such as the kidney, spine and brain. If it isn't treated properly, ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - HIV Negative, Tuberculosis - Resistant, Tuberculosis - HIV Positive, Adrenal Tuberculosis

New TB Test May Help Simplify Diagnosis

Posted 20 Feb 2016 by Drugs.com

FRIDAY, Feb. 19, 2016 – A simple new blood test for tuberculosis may one day help improve diagnosis and treatment of the deadly disease in developing countries, researchers report. The inexpensive test identifies a gene expression "signature" that distinguishes people with active TB from those with either latent TB or other diseases, according to the research team from the Stanford University School of Medicine, in Palo Alto, Calif. The work is outlined in a paper published online Feb. 19 in The Lancet Respiratory Medicine journal. Each year, 9.6 million people worldwide are newly infected with TB, a bacterial infection that usually affects the lungs, and 1.5 million die from the difficult-to-diagnose disease, the researchers noted. "One-third of the world's population is currently infected with TB. Even if only 10 percent of them get active TB, that's still 3 percent of the world's ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis, Tuberculosis - Resistant, Tuberculosis - HIV Negative, Tuberculous Esophagitis, Adrenal Tuberculosis, Tuberculosis - HIV Positive, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy

TB Cases Falling for Foreign-Born People in U.S.

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Tuberculosis cases among foreign-born people in the United States fell by one-fifth in recent years, and the reasons for the decline depend on people's country of origin, a new study suggests. Tuberculosis (TB) is a bacterial infection affecting the lungs and sometimes other organs. Overall, TB cases in the United States decreased over the past two decades, but TB cases among foreign-born people remained higher than in the general population, the study authors said. Between 2007 and 2011, there was a 19 percent drop in TB cases among all foreign-born people in the nation, according to researchers from the U.S. Centers for Disease Control and Prevention. TB cases declined in people recently arriving from Mexico, China, India, the Philippines and Vietnam – the five countries that account for most of the foreign-born people with TB in the United States, the ... Read more

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Toxic Chemicals May Weaken Infants' Response to TB Vaccine

Posted 18 Dec 2015 by Drugs.com

FRIDAY, Dec. 18, 2015 – Exposure to toxic chemicals while in the womb or in early life may weaken a baby's immune system response to the tuberculosis (TB) vaccine, researchers say. The study focused on two common toxins: PCBs, an industrial chemical; and DDT, used in pesticides. These so-called "persistent" pollutants are not easily broken down and remain a health threat years after being banned. PCBs were banned in the United States in 1979. DDT is banned in the United States, but is still used in some countries to control malaria-carrying mosquitoes, the study authors, from the University of Rochester in New York, said in a university news release. The researchers analyzed blood samples and immune responses from 516 pairs of mothers and infants in an area of Slovakia heavily contaminated with environmental toxins. Each baby received the tuberculosis vaccine in their first four days ... Read more

Related support groups: Tuberculosis, BCG, Poisoning, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Toxic Reactions Incl Drug and Substance Abuse, Tubersol, Tuberculin Purified Protein Derivative, Tuberculosis - Extrapulmonary, Tice BCG, Aplisol, Tice BCG Vaccine, Tuberculosis - Resistant, Tuberculous Meningitis, Tuberculin Tine Test, Vaccination and Prophlaxis, Aplitest

Swiss Report Highlights Danger of Drug-Resistant Tuberculosis

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – A new report on a patient in Switzerland who nearly died after catching a highly drug-resistant strain of tuberculosis illustrates exactly what public health officials around the world fear most. Although antibiotics have largely eradicated tuberculosis in the United States in recent decades, experts say evidence is mounting that the bacteria is becoming increasingly resistant to these medications. Details of the Swiss case are reported in the Nov. 12 issue of the New England Journal of Medicine by lead investigator Sebastien Gagneux, head of tuberculosis research with the Swiss Tropical and Public Health Institute at the University of Basel, and colleagues. Normally, Gagneux said, tuberculosis patients are treated for six months with a daily drug "cocktail" comprised of four different first-line medications. The goal: to hem in tuberculosis (TB) while ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculous Meningitis, Tuberculosis - Resistant, Bedaquiline, Tuberculous Esophagitis, Adrenal Tuberculosis, Sirturo, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy

E-Pillboxes Improve Medication Adherence, Study Finds

Posted 15 Sep 2015 by Drugs.com

TUESDAY, Sept. 15, 2015 – Electronic reminders may help people with tuberculosis take their medication properly, a new study suggests. Tuberculosis (TB) patients are less likely to miss doses when they receive alerts from an electronic pillbox, researchers report in the Sept. 15 issue of PLOS Medicine. Electronic pillboxes use visual, audio and/or vibration cues to signal when it's time to take medication. TB is a bacterial infection that mainly strikes the lungs. The traditional method of ensuring medical adherence in TB patients is to watch people take their medicine, but the study authors said this isn't doable in remote areas such as rural China. "Innovative approaches to enable patients to adhere to TB treatment are needed. Widespread use of medication monitors in national TB control programs can benefit from the development of a low-cost and reliable medication monitor as well as ... Read more

Related support groups: Isoniazid, Tuberculosis, Rifampin, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Tuberculosis - Extrapulmonary, Rifamate, Isoniazid/Rifampin, Rifabutin, Rifater, Myambutol, Rifadin, Mycobutin, Rifadin IV, Rifapentine, Isoniazid/Pyrazinamide/Rifampin, Nydrazid

U.S. Health Officials Search for Those Exposed to Drug-Resistant TB

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – U.S. health authorities are trying to find anyone who may have had contact with a woman who has been diagnosed with a highly drug-resistant form of tuberculosis. The woman flew from India to Chicago in April. She then traveled to Missouri and Tennessee before returning to Chicago, where she sought treatment at a hospital about seven weeks after arriving in the United States, The New York Times reported late Monday. At the hospital, the woman was diagnosed with extensively drug-resistant tuberculosis (XDR-TB). On Friday, she was transferred by special air and ground ambulances to a U.S. National Institutes of Health (NIH) hospital in Bethesda, Md. The woman is in an isolation room and the hospital "is providing care and treatment for the patient in connection with an existing NIH clinical protocol for treating TB, including XDR forms," the NIH said. The U.S. ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Tuberculosis - Prophylaxis, Tuberculosis - Resistant, Vaccination and Prophlaxis

TB Vaccine May Work Against Multiple Sclerosis: Study

Posted 4 Dec 2013 by Drugs.com

WEDNESDAY, Dec. 4, 2013 – A vaccine normally used to thwart the respiratory illness tuberculosis also might help prevent the development of multiple sclerosis, a disease of the central nervous system, a new study suggests. In people who had a first episode of symptoms that indicated they might develop multiple sclerosis (MS), an injection of the tuberculosis vaccine lowered the odds of developing MS, Italian researchers report. "It is possible that a safe, handy and cheap approach will be available immediately following the first [episode of symptoms suggesting MS]," said study lead author Dr. Giovanni Ristori, of the Center for Experimental Neurological Therapies at Sant'Andrea Hospital in Rome. But, the study authors cautioned that much more research is needed before the tuberculosis vaccine could possibly be used against multiple sclerosis. In people with MS, the immune system ... Read more

Related support groups: Multiple Sclerosis, BCG, Tuberculosis - Prophylaxis, Tice BCG, Tice BCG Vaccine, TheraCys

Vaccinations Aren't Just for Kids

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Public health experts often focus immunization awareness efforts toward protecting children, and with good reason: Facing a potentially bewildering schedule of vaccinations for their young ones, parents usually need all the help they can get. But vaccinations aren't just kid stuff. Medical science is creating an increasing number of immunizations targeted at adults, to help them avoid life-threatening diseases in middle-age and opportunistic infections when they're older. "Immunization is a life-long issue that we need to pay a lot of attention to," said Dr. Georges C. Benjamin, executive director of the American Public Health Association. Some adult vaccinations are very well-known, like the annual shot that aims to prevent the spread of influenza. "You need an influenza shot every year," Benjamin said. "Part of that is because the virus changes every year, ... Read more

Related support groups: Pneumonia, Human Papilloma Virus, Meningitis, Tetanus, BCG, Zostavax, Yellow Fever Vaccine, Condylomata Acuminata, Cervical Cancer, Gardasil, Prevnar 13, Prevnar, Varicella-Zoster, Measles, Tetanus Toxoid, Vivotif Berna, Tuberculosis - Prophylaxis, Rubella, Rabies Vaccine, Human Diploid Cell, Hepatitis B Adult Vaccine

New Combo Therapy May Prevent TB, Save Lives in People With HIV

Posted 6 Jul 2011 by Drugs.com

WEDNESDAY, July 6 – Simpler and shorter treatment with antibiotic drugs could help prevent full-blown tuberculosis in millions of people worldwide infected with the bacterium that causes TB, especially those also infected with HIV, researchers report. TB, or tuberculosis, is the leading cause of death among people co-infected with HIV, the virus that causes AIDS. About half a million people with both infections die worldwide every year. The new study by an international team of scientists included 1,148 South African men and women infected with the TB bacterium and HIV, who were followed for up to six years to see whose TB infections stayed dormant. It found that the most streamlined combination treatment – a high dose of 900 milligrams each of the newer antibiotic rifapentine (Priftin) and the traditional anti-TB antibiotic isoniazid once weekly for three months – worked as well or ... Read more

Related support groups: Isoniazid, Tuberculosis - Prophylaxis, Priftin, Nydrazid, Rifapentine

New TB Vaccine Passes Safety Trial

Posted 8 Apr 2009 by Drugs.com

WEDNESDAY, April 8 – An experimental tuberculosis vaccine called MVA85A proved safe in a small phase I clinical trial. The study included 12 people with latent tuberculosis infection, which, when re-activated, can cause full-blown TB. It's believed that about a third of the world's population has this latent infection. The participants, who had no other complicating factors, such as hepatitis or HIV, were given the vaccine and then followed for a year. The researchers concluded that the vaccine was safe, did not produce any immunopathology and was immunogenic in the patients. Some participants had side effects that included fever, headache, fatigue and mild concerns at the site of the vaccination. The findings appear in the April 15 issue of the American Journal of Respiratory and Critical Care Medicine. This study could be an important step forward in efforts to introduce a new ... Read more

Related support groups: Tuberculosis - Latent, Tuberculosis - Prophylaxis

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