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Tuberculosis - Latent News

Related terms: Latent Tuberculosis

Global Efforts to Combat TB Epidemic Falling Short

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Countries around the world need to work harder to combat tuberculosis infections and deaths, a new World Health Organization report says. Nations across the globe have pledged to reduce tuberculosis (TB) infections by 80 percent and TB deaths by 90 percent by 2030, but they must work faster if they want to meet these goals, according to the WHO. "We face an uphill battle to reach the global targets for tuberculosis," WHO Director General Dr. Margaret Chan said in an organization news release. "There must be a massive scale-up of efforts, or countries will continue to run behind this deadly epidemic and these ambitious goals will be missed." Tuberculosis is a disease that mainly affects the lungs. The bacteria that cause TB are primarily spread from person to person through tiny droplets from coughs and sneezes. The global response to the TB epidemic did manage ... Read more

Related support groups: Tuberculosis, Rifampin, Tuberculosis - Latent, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifabutin, Rifamate, Myambutol, Rifater, Tuberculosis - Resistant, Mycobutin, Rifadin, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown

Tuberculosis Decline in U.S. Has Stalled, CDC Reports

Posted 24 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – Two decades of progress toward eliminating tuberculosis in the United States has stalled, with incidence of the lung disease holding steady from 2013 to 2015, a federal government report shows. "Resuming progress toward TB elimination in the United States will require intensification of efforts both in the U.S. and globally," said researchers from the U.S. Centers for Disease Control and Prevention's National Tuberculosis Surveillance System. If not treated, TB can be fatal. The bacterial infection is spread through the air, when someone infected coughs, sneezes or speaks. However, it is not easily transmitted – you must be in close contact with someone who has TB for a long period of time, according to the American Lung Association. Overall, TB incidence leveled off at about three new cases per 100,000 people each year between 2013 and 2015, according to ... Read more

Related support groups: Xifaxan, Tuberculosis, Rifampin, Rifaximin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifamate, Rifabutin, Mycobutin, Tuberculosis - Resistant, Rifadin, Tuberculosis - HIV Negative, Rifater, Tuberculosis - HIV Positive, Rimactane, IsonaRif

Screen High-Risk Adults for Tuberculosis, Experts Say

Posted 8 Mar 2016 by Drugs.com

TUESDAY, March 8, 2016 – Adults at greater risk for latent tuberculosis infection should be screened for the condition, the U.S. Preventive Services Task Force recommends. "The task force recommends that primary care clinicians screen adults at increased risk for [latent TB] to help prevent the progression to active TB," panel member Dr. Francisco Garcia said in a task force news release. Garcia is director and chief medical officer of the Pima County Health Department in Tucson, Ariz. Tuberculosis, commonly known as TB, is an infection caused by bacteria. Anyone in close contact with someone with tuberculosis may be exposed to the bacteria. It spreads through the air when an infected person coughs or sneezes, according to the health panel. TB usually attack the lungs, but the bacteria can attack any part of the body such as the kidney, spine and brain. If it isn't treated properly, ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - HIV Negative, Tuberculosis - Resistant, Adrenal Tuberculosis, Tuberculosis - HIV Positive

New TB Test May Help Simplify Diagnosis

Posted 20 Feb 2016 by Drugs.com

FRIDAY, Feb. 19, 2016 – A simple new blood test for tuberculosis may one day help improve diagnosis and treatment of the deadly disease in developing countries, researchers report. The inexpensive test identifies a gene expression "signature" that distinguishes people with active TB from those with either latent TB or other diseases, according to the research team from the Stanford University School of Medicine, in Palo Alto, Calif. The work is outlined in a paper published online Feb. 19 in The Lancet Respiratory Medicine journal. Each year, 9.6 million people worldwide are newly infected with TB, a bacterial infection that usually affects the lungs, and 1.5 million die from the difficult-to-diagnose disease, the researchers noted. "One-third of the world's population is currently infected with TB. Even if only 10 percent of them get active TB, that's still 3 percent of the world's ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Tuberculosis - Resistant, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis, Tuberculous Esophagitis, Adrenal Tuberculosis, Tuberculosis - HIV Positive, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy

TB Cases Falling for Foreign-Born People in U.S.

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Tuberculosis cases among foreign-born people in the United States fell by one-fifth in recent years, and the reasons for the decline depend on people's country of origin, a new study suggests. Tuberculosis (TB) is a bacterial infection affecting the lungs and sometimes other organs. Overall, TB cases in the United States decreased over the past two decades, but TB cases among foreign-born people remained higher than in the general population, the study authors said. Between 2007 and 2011, there was a 19 percent drop in TB cases among all foreign-born people in the nation, according to researchers from the U.S. Centers for Disease Control and Prevention. TB cases declined in people recently arriving from Mexico, China, India, the Philippines and Vietnam – the five countries that account for most of the foreign-born people with TB in the United States, the ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Rifamate, Rifabutin, Isoniazid/Rifampin, Mycobutin, Tuberculosis - Resistant, Rifadin, Tuberculous Meningitis, Rifater, Tuberculosis - Urinary Tract, Isoniazid/Pyrazinamide/Rifampin, Rimactane, IsonaRif

Toxic Chemicals May Weaken Infants' Response to TB Vaccine

Posted 18 Dec 2015 by Drugs.com

FRIDAY, Dec. 18, 2015 – Exposure to toxic chemicals while in the womb or in early life may weaken a baby's immune system response to the tuberculosis (TB) vaccine, researchers say. The study focused on two common toxins: PCBs, an industrial chemical; and DDT, used in pesticides. These so-called "persistent" pollutants are not easily broken down and remain a health threat years after being banned. PCBs were banned in the United States in 1979. DDT is banned in the United States, but is still used in some countries to control malaria-carrying mosquitoes, the study authors, from the University of Rochester in New York, said in a university news release. The researchers analyzed blood samples and immune responses from 516 pairs of mothers and infants in an area of Slovakia heavily contaminated with environmental toxins. Each baby received the tuberculosis vaccine in their first four days ... Read more

Related support groups: Tuberculosis, BCG, Poisoning, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Toxic Reactions Incl Drug and Substance Abuse, Diagnosis and Investigation, Tubersol, Tuberculin Purified Protein Derivative, Tuberculosis - Extrapulmonary, Tice BCG, Aplisol, Tuberculous Meningitis, Tuberculin Tine Test, Vaccination and Prophlaxis, Tice BCG Vaccine, Tuberculosis - Resistant, Aplitest

Assessing Health Issues of Child Refugees

Posted 29 Nov 2015 by Drugs.com

FRIDAY, Nov. 27, 2015 – The main health problems of refugee children from Asia and Africa when they arrive in the United States are outlined in a new study. Based on screenings of more than 8,100 young refugees between 2006 and 2012, the top health concerns were hepatitis B, tuberculosis, parasitic worms, high blood lead levels and anemia, the study found. The refugees, all younger than 19, were from Bhutan, Myanmar, the Democratic Republic of the Congo, Ethiopia, Iraq and Somalia. The screenings were conducted shortly after they arrived in Colorado, Minnesota, Pennsylvania and Washington state. In general, these conditions were more common among children from the Democratic Republic of the Congo, Ethiopia and Somalia, and lower among those from Iraq, researchers said. Among refugees from Myanmar, those who came to the United States from Thailand had more diseases than those who came ... Read more

Related support groups: Anemia, Hepatitis B, Tuberculosis - Latent, Tuberculosis - Active, Lead Poisoning, Helminthic Infection, Worms and Flukes

Doctors Save Life of U.S. Child With Drug-Resistant Tuberculosis

Posted 16 Nov 2015 by Drugs.com

SUNDAY, Nov. 15, 2015 – A 5-year-old child from the United States, stricken at age 2 with a deadly form of tuberculosis after traveling to India, is finally in remission, researchers report. The case, one of only a handful reported in the medical literature, highlights the difficulties of treating an extensively drug-resistant form of tuberculosis, known as XDR TB, in children, the researchers said. The case also highlights the growing global threat of this virulent form of TB and the risk to Americans traveling in countries where there is a high burden of disease. A detailed account of the child's diagnosis and treatment, and the obstacles that clinicians at Johns Hopkins Children's Center in Baltimore faced, was published in the Nov. 16 online edition of The Lancet Infectious Diseases. Study co-author Dr. Sanjay Jain, an associate professor of pediatrics and international health at ... Read more

Related support groups: Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Diagnosis and Investigation, Computed Tomography, Tuberculosis - Resistant

Swiss Report Highlights Danger of Drug-Resistant Tuberculosis

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – A new report on a patient in Switzerland who nearly died after catching a highly drug-resistant strain of tuberculosis illustrates exactly what public health officials around the world fear most. Although antibiotics have largely eradicated tuberculosis in the United States in recent decades, experts say evidence is mounting that the bacteria is becoming increasingly resistant to these medications. Details of the Swiss case are reported in the Nov. 12 issue of the New England Journal of Medicine by lead investigator Sebastien Gagneux, head of tuberculosis research with the Swiss Tropical and Public Health Institute at the University of Basel, and colleagues. Normally, Gagneux said, tuberculosis patients are treated for six months with a daily drug "cocktail" comprised of four different first-line medications. The goal: to hem in tuberculosis (TB) while ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculosis - Resistant, Tuberculous Meningitis, Tuberculous Esophagitis, Adrenal Tuberculosis, Sirturo, Tuberculosis - Urinary Tract, Ocular Tuberculosis, Tuberculous Pleurisy, Bedaquiline

U.S. Health Officials Search for Those Exposed to Drug-Resistant TB

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – U.S. health authorities are trying to find anyone who may have had contact with a woman who has been diagnosed with a highly drug-resistant form of tuberculosis. The woman flew from India to Chicago in April. She then traveled to Missouri and Tennessee before returning to Chicago, where she sought treatment at a hospital about seven weeks after arriving in the United States, The New York Times reported late Monday. At the hospital, the woman was diagnosed with extensively drug-resistant tuberculosis (XDR-TB). On Friday, she was transferred by special air and ground ambulances to a U.S. National Institutes of Health (NIH) hospital in Bethesda, Md. The woman is in an isolation room and the hospital "is providing care and treatment for the patient in connection with an existing NIH clinical protocol for treating TB, including XDR forms," the NIH said. The U.S. ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Tuberculosis - Prophylaxis, Tuberculosis - Resistant, Vaccination and Prophlaxis

18th Century Mummies Reveal How TB Spread Through Europe

Posted 8 Apr 2015 by Drugs.com

WEDNESDAY, April 8, 2015 – Naturally mummified bodies from an 18th century crypt in Hungary provide new insight into tuberculosis infections in Europe during that time, researchers say. The discovery could also help health officials fight future tuberculosis (TB) outbreaks, the scientists suggested. Analyses of samples taken from the bodies in the crypt in the Dominican church of Vac uncovered 14 TB genomes. The research suggests that some of the victims had several strains of TB, perhaps a common occurrence when the disease was at its peak in Europe, the researchers said. "Microbiological analyses of samples from contemporary TB patients usually report a single strain of tuberculosis per patient. By contrast, five of the eight bodies in our study yielded more than one type of tuberculosis – remarkably from one individual we obtained evidence of three distinct strains," study author ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active

Sanofi Receives FDA Approval of Priftin (rifapentine) for Latent Tuberculosis Infection

Posted 2 Dec 2014 by Drugs.com

Bridgewater, NJ – December 2, 2014 / PR Newswire / — Sanofi announced today that following a priority review, the U.S. Food and Drug Administration has approved Priftin (rifapentine) in combination with isoniazid (INH) for a new indication for the treatment of latent tuberculosis infection (LTBI) in patients two years of age and older at high risk of progression to tuberculosis (TB) disease. Priftin is an antimycobacterial that has been approved since 1998, in combination with one or more antituberculosis drugs, for the treatment of active pulmonary TB caused by Mycobacterium tuberculosis. A person with LTBI is infected with the bacteria that cause TB, but does not feel sick, have symptoms, and cannot spread the bacteria to others. More than 11 million people living in the United States have LTBI, and about five to 10 percent of those – up to more than 1 million people – will develop TB ... Read more

Related support groups: Tuberculosis - Latent, Tuberculosis - Active, Rifapentine, Priftin

CDC Issues New TB Treatment Guidelines

Posted 8 Dec 2011 by Drugs.com

THURSDAY, Dec. 8 – New guidelines on treating so-called "latent" tuberculosis infection in the United States should significantly shorten and simplify the course of the therapy from about 9 months to 3 months, according to the U.S. Centers for Disease Control and Prevention. The new guidelines for public health officials and health care providers – which are based on expert opinion and the results of three clinical trials – are a "game changer" for the treatment of TB in the United States, according to CDC Director Dr. Thomas Frieden. Latent TB infection occurs when a person is infected with TB bacteria but does not yet have symptoms and so cannot transmit the bacteria to others. However, if the bacteria becomes active, the person will develop the disease and can also spread it to others. Certain people, including those with weakened immune systems, are more likely to progress from ... Read more

Related support groups: Tuberculosis, Isoniazid, Tuberculosis - Latent, Priftin, Rifapentine, Nydrazid

New TB Vaccine Passes Safety Trial

Posted 8 Apr 2009 by Drugs.com

WEDNESDAY, April 8 – An experimental tuberculosis vaccine called MVA85A proved safe in a small phase I clinical trial. The study included 12 people with latent tuberculosis infection, which, when re-activated, can cause full-blown TB. It's believed that about a third of the world's population has this latent infection. The participants, who had no other complicating factors, such as hepatitis or HIV, were given the vaccine and then followed for a year. The researchers concluded that the vaccine was safe, did not produce any immunopathology and was immunogenic in the patients. Some participants had side effects that included fever, headache, fatigue and mild concerns at the site of the vaccination. The findings appear in the April 15 issue of the American Journal of Respiratory and Critical Care Medicine. This study could be an important step forward in efforts to introduce a new ... Read more

Related support groups: Tuberculosis - Latent, Tuberculosis - Prophylaxis

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