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Fighting HIV on Multiple Fronts Might Lead to Vaccine

Posted 20 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 20, 2017 – A combination antibody strategy could be the key to halting the spread of HIV, according to results from two promising animal studies. Two separate research groups completely protected their own sets of lab monkeys from HIV infection using this combination vaccination strategy, albeit in two very different ways. One group inoculated their monkeys with a "cocktail" of two HIV antibodies, while the other group genetically engineered a single antibody capable of attacking HIV in three different ways. There's just one downside: Because these antibodies are injected into the body rather than naturally created by the immune system, people will have to receive shots on a regular basis to retain their protection against the AIDS-causing virus. The strategy focuses on broadly neutralizing HIV antibodies, a type of antibody that attaches to the virus and prevents it ... Read more

Related support groups: HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Genvoya, Baraclude, Victrelis, Tenofovir, Viread, Kaletra, Entecavir, Norvir, Lamivudine, Telaprevir, Prezista, Nevirapine, Boceprevir

Truvada Helped Protect Gay Teen Males From HIV

Posted 5 Sep 2017 by Drugs.com

TUESDAY, Sept. 5, 2017 – A group of gay and bisexual teenage males safely used a medication that prevents HIV infection, though some failed to follow the drug regimen fully and became infected, researchers report. People at risk for becoming infected with the virus that causes AIDS can dramatically lower their risk of infection by taking the drug Truvada in what is known as the PrEP regimen, but its use is only approved for adults. "Several studies have shown that daily oral PrEP is effective in preventing HIV among people at high risk of becoming infected, but none of them included adolescents under age 18," explained study author Dr. Bill Kapogiannis, of the U.S. National Institute of Child Health and Human Development. "Our study suggests that this therapy can safely reduce HIV risk for those under 18." For the study, researchers led by Sybil Hosek, of the Cook County Health & ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis, Truvada

HIV Treatment Protects Uninfected Partner From the Virus

Posted 26 Jul 2017 by Drugs.com

TUESDAY, July 25, 2017 – HIV treatment prevented transmission of the virus in gay couples when only one partner had the virus, a new study shows. The research included 358 such gay couples in Australia, Brazil and Thailand. The HIV-positive partners received treatment that reduced the amount of virus in the blood to undetectable levels. The participants were followed from 2012 to 2016. During that time, the couples reported nearly 17,000 instances of anal intercourse without a condom. None resulted in HIV transmission, the study authors said. "Undetectable virus level effectively prevents HIV transmission among gay couples," said chief study investigator Andrew Grulich, a professor at the Kirby Institute at the University of New South Wales in Australia. "This is life-changing news for couples of differing HIV status. But it is important that the HIV positive partner is under regular ... Read more

Related support groups: HIV Infection, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Truvada, Baraclude, Victrelis, Oseltamivir, Tenofovir, Viread, Kaletra, Entecavir, Norvir, Telaprevir, Prezista, Lamivudine, Reyataz, Ritonavir, Nevirapine, Boceprevir

Meds by Monthly Injection Might Revolutionize HIV Care

Posted 24 Jul 2017 by Drugs.com

MONDAY, July 24, 2017 – Getting a shot of medication to control HIV every month or two instead of having to take pills every day could transform the way the virus is kept at bay. New research suggests that injectable, long-acting antiretroviral therapy for HIV is as safe and effective as oral medications. The injection – given every four or eight weeks – includes the drugs cabotegravir and rilpivirine. "We have made considerable advances in the treatment of HIV over the last several decades," said study lead author Dr. David Margolis. "But for many patients living with HIV, it still remains a challenge to take daily oral medication, either because they are unable to or they choose not to. So it is important to find alternatives." Margolis is medical director of ViiV Healthcare in Research Triangle Park, N.C., the developer of this new approach and the company that funded the trial. ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Incivek, Truvada, Baraclude, Victrelis, Viread, Tenofovir, Kaletra, Entecavir, Norvir, Telaprevir, Lamivudine, Prezista, Boceprevir, Nevirapine, Reyataz, Ritonavir, Epivir, Lexiva

Wider Access to Meds Cuts Global AIDS Deaths in Half

Posted 20 Jul 2017 by Drugs.com

THURSDAY, July 20, 2017 – AIDS-related deaths worldwide have been halved since 2005 as more people were able to get lifesaving drugs, UNAIDS (a United Nations Program) says in a new report. In 2016, 19.5 million (53 percent) of the almost 37 million people living with HIV (the virus that causes AIDS) had access to HIV treatment. AIDS-related deaths fell from 1.9 million in 2005 to 1 million in 2016. If the treatment trend continues, the goal to provide drugs for 30 million HIV patients by 2020 will be achieved, according to the report. "We met the 2015 target of 15 million people on treatment and we are on track to double that number to 30 million and meet the 2020 target," said Michel Sidibe, executive director of UNAIDS. "We will continue to scale up to reach everyone in need and honor our commitment of leaving no one behind," Sidibe said in a program news release. The greatest ... Read more

Related support groups: HIV Infection, Atripla, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Baraclude, Victrelis, Oseltamivir, Viread, Tenofovir, Kaletra, Norvir, Entecavir, Lamivudine, Telaprevir, Prezista, Boceprevir

Could a Monetary Perk Help Keep HIV Patients on Their Meds?

Posted 22 Jun 2017 by Drugs.com

WEDNESDAY, June 21, 2017 – There are mixed results from a new study on the use of monetary rewards to help boost the odds that HIV-infected patients will enter care, and take their meds as directed. The study, conducted at HIV clinics in New York City and Washington, D.C., found that financial incentives such as gift cards could improve the likelihood that HIV patients would take antiretroviral medications that suppress the AIDS-causing virus. But the effect was modest in patients already receiving care, and the gift cards had little effect on increasing the number of new HIV-positive patients who got treated, the study authors said. Still, lead author Dr. Wafaa El-Sadr called the results "encouraging" and said they "should motivate efforts to pursue the further assessment of using financial incentives in HIV treatment programs and to determine their potential impact when scaled up." ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Epclusa, Truvada, Triumeq, Stribild, Zepatier, Complera, Genvoya, Baraclude, Victrelis, Viread, Tenofovir, Viekira Pak, Kaletra, Entecavir, Norvir

6 Experts Resign from President's HIV/AIDS Advisory Panel in Protest

Posted 19 Jun 2017 by Drugs.com

Six experts resigned from the Presidential Advisory Council on HIV/AIDS because Donald Trump "simply does not care," one of the members wrote in an op/ed piece in Newsweek. Scott Schoettes, counsel and HIV Project Director at Lambda Legal, and five other members resigned on June 13. The council provides advice, information, and recommendations to the Secretary of Health and Human Services to promote effective treatment, prevention, and an eventual cure for HIV. However, as "advocates for people living with HIV, we have dedicated our lives to combating this disease and no longer feel we can do so effectively within the confines of an advisory body to a president who simply does not care," Schoettes wrote in the article published June 16. "The Trump Administration has no strategy to address the on-going HIV/AIDS epidemic, seeks zero input from experts to formulate HIV policy, and – most ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada, Baraclude, Tenofovir, Viread, Entecavir, Lamivudine, Nevirapine, Zidovudine, Epivir, Abacavir, Hepsera, Didanosine, Sustiva, Efavirenz, Adefovir, Stavudine, Viramune, Ziagen

FDA Approves First Generic Truvada for HIV Infection and Pre-Exposure Prophylaxis (PrEP)

Posted 14 Jun 2017 by Drugs.com

June 8, 2017 - The U.S. Food and Drug Administration has approved the first generic version of Truvada for the treatment of HIV-1, in combination with other antiretroviral agents, and for pre-exposure prophylaxis (PrEP) in combination with safer sex practices to prevent sexually-acquired HIV infection in adults at high risk. PrEP may be part of a comprehensive HIV prevention strategy that includes safer sex practices, such as consistent and correct condom use, regular HIV testing and risk reduction counseling. As part of PrEP, HIV-uninfected individuals who are at high risk of sexually acquired HIV infection take antiretroviral medication daily to try to lower their chances of becoming infected with HIV if they are exposed to the virus. The most common side effects reported by HIV-1 infected individuals using emtricitabine and tenofovir disoproxil fumarate in clinical trials included ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada, Emtricitabine/Tenofovir

Americans With HIV Staying on Lifesaving Meds Longer

Posted 31 May 2017 by Drugs.com

WEDNESDAY, May 31, 2017 – More Americans with HIV are sticking with medications that turn a fatal disease into a manageable condition, a new study shows. "This represents a lot of people who are not dying and not infecting others," said study corresponding author Ira Wilson, chair of Brown University's Health Services Policy and Practice Department, in Providence, R.I. "These differences represent tremendous, very real benefit," he added in a university news release. While there have been significant increases in how long HIV patients take their medications, many people still stop taking the drugs after a few years, the researchers cautioned. In the study, the researchers analyzed data from nearly 43,600 Medicaid patients in 14 states from 2001 to 2010, and found the length of time patients kept taking antiretroviral medications increased more than 50 percent. In 2001-2003, half of ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Epclusa, Incivek, Truvada, Triumeq, Stribild, Zepatier, Complera, Genvoya, Baraclude, Victrelis, Viread, Tenofovir, Viekira Pak, Kaletra, Entecavir, Norvir

Gay Men Less Likely to Have Safe Sex Now: Survey

Posted 13 Feb 2017 by Drugs.com

MONDAY, Feb. 13, 2017 – In a sign that powerful new ways to treat and prevent HIV are relaxing attitudes about safer sex, a new survey finds that gay and bisexual men are much less likely to use condoms than they were two decades ago. Men questioned at a Atlanta gay pride event in 2015 – including HIV-positive men – were more likely to say they'd recently had anal sex without a condom compared to men who were questioned at the same event in 2006 and 1997. Although there are signs that the rates of other sexually transmitted infections have increased and the possibility of a drug-resistant strain of the once-deadly virus looms, HIV experts said the condom-less trend may not be as troubling as it appears. "There has been an increase in the understanding that condom-less anal sex is not risky" if men take a drug to prevent HIV infection or take medication if they are already infected, ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Provera, Mirena, Nexplanon, Depo-Provera, NuvaRing, Sprintec, Implanon, Ortho Tri-Cyclen, Tri-Sprintec, Microgestin Fe 1/20, Yasmin, Loestrin 24 Fe, Plan B One-Step, Ortho Evra, TriNessa, Lutera

Black Americans Still Undertreated for HIV

Posted 3 Feb 2017 by Drugs.com

FRIDAY, Feb. 3, 2017 – Although progress has been made, blacks in America are still being hit harder by HIV/AIDS, a new report from the U.S. Centers for Disease Control and Prevention says. The CDC study found that of more than 12,200 black men and women diagnosed with HIV in 2014, nearly 22 percent had progressed to AIDS by the time they were diagnosed. That means diagnosis and treatment is often coming too late. Moreover, among all black Americans with HIV in 2013, only about 54 percent were receiving continuous medical care. Of those getting care, less than half had effectively suppressed the virus. This is far below the National HIV/AIDS Strategy goals of 90 percent of HIV patients in treatment and 80 percent with undetectable HIV by 2020, the study authors noted. "While we have made great progress in HIV prevention among African Americans in recent years, it is clear that we need ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Tamiflu, Pre-Exposure Prophylaxis, Valacyclovir, Ribavirin, Incivek, Zovirax, Truvada, Famciclovir, Baraclude, Victrelis, Famvir, Oseltamivir, Tenofovir, Viread, Kaletra, Valcyte, Entecavir

Gay Man Infected With HIV Despite Using Preventive Drugs

Posted 1 Feb 2017 by Drugs.com

WEDNESDAY, Feb. 1, 2017 – Doctors report that a gay Canadian man contracted HIV even though he had been taking daily medication to ward off infection. Based on a genetic analysis of the virus, it was determined that the 43-year-old Toronto resident was infected with a strain of HIV that had become resistant to the anti-HIV drug Truvada, said report author Dr. David Knox. He is a doctor with the Maple Leaf Medical Clinic in Toronto. However, HIV experts say this does not mean a completely drug-resistant strain of the virus is on its way, leading to a return of the AIDS crisis of the 1980s and 1990s. "The number of highly resistant strains for Truvada is still very low," said Greg Millett, vice president and director of public policy for amfAR, The Foundation for AIDS Research. "Less than 1 percent of people living with HIV have a highly resistant strain. I do not have a concern that ... Read more

Related support groups: Plan B, Provera, Mirena, Nexplanon, Depo-Provera, NuvaRing, Sprintec, Implanon, Ortho Tri-Cyclen, Tri-Sprintec, Microgestin Fe 1/20, Yasmin, Loestrin 24 Fe, Plan B One-Step, Ortho Evra, TriNessa, Lutera, Mononessa, Ortho Tri-Cyclen Lo, Yaz

Doctors Seeing More HIV Patients With Multidrug Resistance

Posted 1 Dec 2016 by Drugs.com

THURSDAY, Dec. 1, 2016 – A significant number of people with HIV have strains of the AIDS-causing virus that are resistant to both older and newer drugs, researchers report. The researchers looked at 712 HIV patients worldwide whose infection was not controlled by antiretroviral drugs. They found that 16 percent of patients whose infection was resistant to modern drugs had HIV mutations linked with resistance to older drugs called thymidine analogues. Among patients whose HIV had this mutation, 80 percent were also resistant to tenofovir, the main drug in most modern HIV treatment and prevention programs, the researchers reported. The findings were published in the Nov. 30 issue of The Lancet Infectious Diseases journal. "We were very surprised to see that so many people were resistant to both drugs, as we didn't think this was possible," study lead author Ravi Gupta, of University ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Sovaldi, Incivek, Epclusa, Truvada, Triumeq, Stribild, Zepatier, Complera, Genvoya, Baraclude, Sofosbuvir, Victrelis, Viread, Tenofovir, Viekira Pak, Kaletra

Doctors May Not Be Telling High-Risk Patients About HIV Prevention Drug

Posted 10 Oct 2016 by Drugs.com

MONDAY, Oct. 10, 2016 – Many gay and bisexual men don't know about a drug therapy that can protect them from HIV, a new study suggests. A once-a-day pill, Truvada, known as PrEP – short for pre-exposure prophylaxis medication – has been found to reduce HIV infection by 92 percent in people at high risk for the AIDS-causing virus, including men who have unprotected gay sex, the researchers said. The researchers studied 2014 data from 401 HIV-negative gay and bisexual men in Baltimore. Only 42 percent knew about PrEP. Those who had been tested for HIV in the previous year were more likely to be aware of it. But having recently seen a doctor or getting tested for another sexually transmitted disease did not increase the likelihood that gay or bisexual men knew about the preventive drug, the researchers from the Johns Hopkins Bloomberg School of Public Health found. The findings suggest ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada

HIV Infection Seems to Affect Nervous System

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – Many newly infected HIV patients experience neurological problems, but they tend to be mild and they subside after antiretroviral drugs are given, a new study finds. "We were surprised that neurologic findings were so pervasive in participants diagnosed with very recent HIV infection," said study author Dr. Joanna Hellmuth. She is a clinical fellow in the department of neurology at the University of California, San Francisco (UCSF). "While the findings were mild, it is clear that HIV affects the nervous system within days of infection," she said in a university news release. "Since the majority of these neurologic issues were resolved with treatment, our study reinforces recommendations that people at risk for HIV test often and start antiretroviral treatment immediately if they are infected," Hellmuth added. Among 139 people in Thailand infected with HIV three ... Read more

Related support groups: Peripheral Neuropathy, Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Triumeq, Stribild, Zepatier, Complera, Autonomic Neuropathy, Genvoya, Baraclude, Victrelis, Tenofovir, Viread, Daklinza, Kaletra, Viekira Pak

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