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FDA Approves Expanded Indication for Truvada (emtricitabine and tenofovir disoproxil fumarate) for Reducing the Risk of Acquiring HIV-1 in Adolescents

Posted 16 May 2018 by Drugs.com

FOSTER CITY, Calif.--(BUSINESS WIRE)--May 15, 2018-- Gilead Sciences, Inc. (Nasdaq:GILD) today announced that the U.S. Food and Drug Administration (FDA) has approved once-daily oral Truvada (emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg)—in combination with safer sex practices—to reduce the risk of sexually acquired HIV-1 in at-risk adolescents. The safety and efficacy profile of Tru ...

HIV Drug, Tenofovir, Appears Safe During Pregnancy

Posted 26 Apr 2018 by Drugs.com

WEDNESDAY, April 25, 2018 – Drugs to prevent HIV-positive pregnant women from infecting their unborn babies appear safe and don't raise the risk for premature birth or infant death, new research indicates. The U.S. scientists said their findings should ease worries among expectant mothers treated with antiviral regimens that contain the drug tenofovir disoproxil fumarate (TDF). "The analysis ...

FDA Approves Biktarvy (bictegravir, emtricitabine, tenofovir alafenamide) for Treatment of HIV-1 Infection

Posted 8 Feb 2018 by Drugs.com

FOSTER CITY, Calif.--(BUSINESS WIRE)--Feb. 7, 2018-- Gilead Sciences, Inc. (NASDAQ:GILD) today announced that the U.S. Food and Drug Administration (FDA) has approved Biktarvy (bictegravir 50mg/emtricitabine 200mg/tenofovir alafenamide 25mg, BIC/FTC/TAF), a once-daily single tablet regimen (STR) for the treatment of HIV-1 infection. Biktarvy combines the novel, unboosted integrase strand transfer ...

U.S. Efforts to Help Fight Global HIV Are Paying Off

Posted 25 Jan 2018 by Drugs.com

WEDNESDAY, Jan. 24, 2018 – A U.S. government program to prevent, treat and care for people with HIV/AIDS in poor countries has been highly effective and should continue, experts say. Since 2003, the President's Emergency Plan for AIDS Relief (PEPFAR) has provided drug therapy to more than 13 million men, women and children, as well as voluntary circumcisions to more than 15.2 million men to ...

Coming Soon: A Once-Weekly Pill to Fight HIV?

Posted 9 Jan 2018 by Drugs.com

TUESDAY, Jan. 9, 2018 – Goodbye, daily HIV meds? Researchers say a once-a-week, slow-release pill may keep HIV infections under control and help prevent new HIV infections altogether. The pill in question is still early in development. But it contains the same highly active antiretroviral therapy (HAART) – the drug combination that revolutionized HIV treatment back in the mid-1990s. Those ...

HIV Is Gaining Resistance to Lifesaving Drugs

Posted 1 Dec 2017 by Drugs.com

FRIDAY, Dec. 1, 2017 – A new study warns of a potential return to the "bad old days" when there were no effective drugs to fight HIV, the virus that causes AIDS. Timed for release on Dec. 1, World AIDS Day, the new study looked at data on more than 56,000 adults living with HIV in sub-Saharan Africa, Asia and Latin America. In total, patients in 63 low- and middle-income countries were screened, ...

U.S.-Funded HIV Prevention Effort Reaps Rewards in Uganda

Posted 30 Nov 2017 by Drugs.com

THURSDAY, Nov. 30, 2017 – A program that includes male circumcision and antiviral drug treatment led to a sharp drop in HIV infection rates in a high-risk region of Uganda, researchers report. Their study of a U.S.-funded HIV prevention program in the rural Rakai District on the shore of Lake Victoria followed 34,000 people. The program provides a number of free services, including anti-HIV ...

HIV Diagnoses Occurring More Quickly, CDC Says

Posted 28 Nov 2017 by Drugs.com

TUESDAY, Nov. 28, 2017 – U.S. health care providers are getting better at detecting new cases of HIV infection, although it still can take years for people to know they've acquired the dreaded virus, federal officials reported Tuesday. The average time between HIV infection and diagnosis was three years in 2015, seven months earlier than it had been in 2011, according to researchers from the ...

Almost 21 Million Worldwide Now Have Access to HIV Meds

Posted 21 Nov 2017 by Drugs.com

TUESDAY, Nov. 21, 2017 – The number of people with HIV who take life-saving antiretroviral medications has increased by tens of millions worldwide in recent decades, a United Nations report says. The number rose from 685,000 in 2000 to 20.9 million as of June 2017, according to UNAIDS, the Joint United Nations Program on HIV and AIDS. "Many people do not remember that in 2000 there were only 90 ...

Are HIV and AIDS Poised for a Comeback?

Posted 25 Oct 2017 by Drugs.com

WEDNESDAY, Oct. 25, 2017 – The advent of powerful drugs in the mid-1990s brought remarkable gains in survival for HIV patients who had access to the medications. But a team of experts now warns that the global HIV pandemic continues and is at risk of expanding, given the worrisome global rise of HIV resistance to antiretroviral (ART) medications. "Current trends in HIV drug resistance are very ...

Fighting HIV on Multiple Fronts Might Lead to Vaccine

Posted 20 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 20, 2017 – A combination antibody strategy could be the key to halting the spread of HIV, according to results from two promising animal studies. Two separate research groups completely protected their own sets of lab monkeys from HIV infection using this combination vaccination strategy, albeit in two very different ways. One group inoculated their monkeys with a "cocktail" of ...

Truvada Helped Protect Gay Teen Males From HIV

Posted 5 Sep 2017 by Drugs.com

TUESDAY, Sept. 5, 2017 – A group of gay and bisexual teenage males safely used a medication that prevents HIV infection, though some failed to follow the drug regimen fully and became infected, researchers report. People at risk for becoming infected with the virus that causes AIDS can dramatically lower their risk of infection by taking the drug Truvada in what is known as the PrEP regimen, but ...

HIV Treatment Protects Uninfected Partner From the Virus

Posted 26 Jul 2017 by Drugs.com

TUESDAY, July 25, 2017 – HIV treatment prevented transmission of the virus in gay couples when only one partner had the virus, a new study shows. The research included 358 such gay couples in Australia, Brazil and Thailand. The HIV-positive partners received treatment that reduced the amount of virus in the blood to undetectable levels. The participants were followed from 2012 to 2016. During ...

Meds by Monthly Injection Might Revolutionize HIV Care

Posted 24 Jul 2017 by Drugs.com

MONDAY, July 24, 2017 – Getting a shot of medication to control HIV every month or two instead of having to take pills every day could transform the way the virus is kept at bay. New research suggests that injectable, long-acting antiretroviral therapy for HIV is as safe and effective as oral medications. The injection – given every four or eight weeks – includes the drugs cabotegravir and ...

Wider Access to Meds Cuts Global AIDS Deaths in Half

Posted 20 Jul 2017 by Drugs.com

THURSDAY, July 20, 2017 – AIDS-related deaths worldwide have been halved since 2005 as more people were able to get lifesaving drugs, UNAIDS (a United Nations Program) says in a new report. In 2016, 19.5 million (53 percent) of the almost 37 million people living with HIV (the virus that causes AIDS) had access to HIV treatment. AIDS-related deaths fell from 1.9 million in 2005 to 1 million in ...

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Pre-Exposure Prophylaxis, Nonoccupational Exposure, HIV Infection, Occupational Exposure

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