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Study Questions Use of Migraine Meds in Kids, Teens

Posted 28 Oct 2016 by Drugs.com

THURSDAY, Oct. 27, 2016 – A new study raises questions about the effectiveness of medicines commonly prescribed to prevent migraines in children and teens. The 24-week clinical trial involving 328 patients found no significant differences between the drugs amitriptyline (Elavil), topiramate (Topamax) and a placebo sugar pill in reducing the number of days with a migraine or migraine-related disability. Fifty-two percent of those taking amitriptyline and 55 percent of those taking topiramate saw the number of days they had a headache drop by 50 percent or more, while 61 percent of those taking a placebo pill saw the same benefit, the findings showed. The patients taking the prescription drugs also had much higher rates of side effects, such as fatigue, dry mouth, mood changes, and tingling in the hands, arms, legs or feet. "The study was intended to demonstrate which of the commonly ... Read more

Related support groups: Migraine, Amitriptyline, Topamax, Migraine Prevention, Topiramate, Elavil, Qsymia, Migraine Prophylaxis, Endep, Amitriptyline/Chlordiazepoxide, Limbitrol, Triavil, Limbitrol DS, Topamax Sprinkle, Trokendi XR, Phentermine/topiramate, Qudexy XR, Amitriptyline/Perphenazine, Etrafon Forte, Trochleitis

Experimental Drug Acts Fast Against Chronic Migraine

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – An experimental drug may bring fast relief to people with debilitating chronic migraines, a new study finds. Preliminary trials had already found that the drug – dubbed TEV-48125 – can help prevent migraine attacks in people who've suffered long-term with headaches. Now, the new findings suggest that it starts working within three to seven days of the first injection, researchers reported. "To my knowledge, that's the fastest separation ever demonstrated in chronic migraine," said lead researcher Dr. Marcelo Bigal, of Teva Pharmaceuticals, the company developing TEV-48125. The term "separation" refers to the point at which patients on TEV-48125 started to improve, compared to patients given a placebo (an inactive treatment). TEV-48125 is one of a new class of drugs being developed to prevent migraines. The medications are all antibodies that block a chemical ... Read more

Related support groups: Migraine, Migraine Prevention, Migraine Prophylaxis, Diagnosis and Investigation, Trochleitis

Exploring the Link Between Estrogen and Migraines

Posted 1 Jun 2016 by Drugs.com

WEDNESDAY, June 1, 2016 – Researchers are getting a better understanding of the link between estrogen levels and migraine headaches in women. A new study finds that for women who get these intense headaches, levels of the hormone estrogen drop more rapidly in the days before menstruation than in women without the headaches. "These results suggest that a 'two-hit' process may link estrogen withdrawal to menstrual migraine," said study author Dr. Jelena Pavlovic, of the Albert Einstein College of Medicine/Montefiore Medical Center in New York City. "More rapid estrogen decline may make women vulnerable to common triggers for migraine attacks such as stress, lack of sleep, foods and wine." Researchers looked at urine samples of 114 women with migraines and 223 women without migraines, average age 47. Estrogen levels among those with migraines dropped 40 percent in the days just before ... Read more

Related support groups: Migraine, Estradiol, Migraine Prevention, Premarin, Ethinyl Estradiol, Estrace, Migraine Prophylaxis, Vagifem, Vivelle, Estrace Vaginal Cream, Climara, Vivelle-Dot, Estring, Premarin Vaginal, Estradiol Patch, Minivelle, Cenestin, Evamist, Femring, Enjuvia

Women With Migraine May Face Higher Threat of Heart Disease, Stroke

Posted 1 Jun 2016 by Drugs.com

TUESDAY, May 31, 2016 – Women who suffer from migraine headaches may have a slightly increased risk of heart disease or stroke, a new study suggests. "Migraine should be considered a marker for increased risk of cardiovascular disease, at least in women," said lead researcher Dr. Tobias Kurth, director of the Institute of Public Health at Charite-Universitatsmedizin in Berlin, Germany. But, Kurth cautioned that this study can't prove that migraines cause heart attack or stroke, only that they may make these events more likely. Also, men may be similarly affected. "We have no reason to believe that this is limited to women," Kurth said. Migraines are headaches marked by intense throbbing or pulsing, often accompanied by nausea, vomiting and sensitivity to light and sound. They had previously been linked to an increased risk for stroke, but this new study also ties them to possible heart ... Read more

Related support groups: Migraine, Ischemic Stroke, Heart Attack, Migraine Prevention, Transient Ischemic Attack, Migraine Prophylaxis, Myocardial Infarction, Intracranial Hemorrhage, Trochleitis

Migraines Take Toll on Spouse

Posted 31 May 2016 by Drugs.com

TUESDAY, May 31, 2016 – If you suffer from migraines, your spouse probably suffers, too. That's the conclusion of researchers who surveyed more than 4,000 people with the debilitating headaches and their spouses/domestic partners. "This study highlights the significant burden that migraine can have on a wide range of family activities, parenting responsibilities, spousal relationships and family finances," said lead author Dawn Buse, director of behavioral medicine at Montefiore Headache Center in New York City. More than two out of five people with migraines and 23 percent of their spouses/partners said they believed the person with migraines would be a better parent if they did not have the condition. About half of the people with migraines had missed at least one family activity in the past month because of a migraine, the study found. About one-third of migraine sufferers and 21 ... Read more

Related support groups: Migraine, Ibuprofen, Naproxen, Meloxicam, Advil, Migraine Prevention, Diclofenac, Voltaren, Mobic, Aleve, Fioricet, Motrin, Excedrin, Toradol, Indomethacin, Migraine Prophylaxis, Imitrex, Tylenol PM, Maxalt, Sumatriptan

Health Tip: Have Headaches? Speak to Your Doctor

Posted 24 May 2016 by Drugs.com

-- A headache is generally recognized as having pain or discomfort anywhere in the head, scalp or neck. It can be a symptom of everything from minor stress to a life-threatening stroke. Learning all you can about your condition is a first step on the road to treatment and prevention. The National Headache Foundation suggests: Learn as much a possible, such as what's probably causing your headaches and how to prevent them. Focus on the most important questions, and get answers to less important questions later. Voice any concerns or fears about your headaches to your doctor. If you don't understand something, ask the doctor for an explanation. Read more

Related support groups: Headache, Migraine, Ibuprofen, Naproxen, Meloxicam, Advil, Migraine Prevention, Diclofenac, Voltaren, Mobic, Aleve, Fioricet, Motrin, Excedrin, Cluster Headaches, Indomethacin, Toradol, Migraine Prophylaxis, Imitrex, Tylenol PM

Scientists Discover Substance That Causes Pain

Posted 28 Apr 2010 by Drugs.com

WEDNESDAY, April 28 – The human body produces a substance similar to capsaicin – which makes chili peppers hot – at sites of pain, and blocking production of this substance can ease pain, a new study shows. The findings may lead to the development of non-addictive painkillers, according to the researchers at the University of Texas Health Science Center in San Antonio. In work with mice, the scientists found that a family of fatty acids called oxidized linoleic acid metabolites (OLAMs) play an important role in the biology of pain. "This is a major breakthrough in understanding the mechanisms of pain and how to more effectively treat it," senior investigator Kenneth Hargreaves, chair of the Department of Endodontics in the Dental School at the UT Health Sciences Center, said in an UT news release. "These data demonstrate, for the first time, that OLAMs constitute a new family of ... Read more

Related support groups: Pain, Headache, Fibromyalgia, Back Pain, Migraine, Muscle Pain, Neuralgia, Sciatica, Migraine Prevention, Breakthrough Pain, Neck Pain, Herniated Disc, Scoliosis, Cluster Headaches, Migraine Prophylaxis, Frozen Shoulder, Spondylolisthesis, New Daily Persistent Headache, Costochondritis, Epicondylitis - Tennis Elbow

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