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U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Colorectal Cancer, Lung Cancer, Rituxan, Isotretinoin, Claravis

'Precision' Cancer Treatment May Extend Lives

Posted 20 May 2016 by Drugs.com

THURSDAY, May 19, 2016 – "Precision" cancer treatment that's guided by genetic clues from the patient's own tumor appears to outperform traditional chemotherapy, a new research review finds. Patients given precision – or personalized – treatment experienced a tumor shrinkage rate six times that attained by regular chemotherapy. But, that only happened if doctors used genetic information to choose the appropriate targeted therapy, said lead researcher Maria Schwaederle. Those patients also experienced nearly double the length of time before their cancer resumed growing, according to the analysis of nearly 350 clinical trials. "It is not just that the therapies are better, but that targeted therapies must be given to the right patients," said Schwaederle, who's with the University of California, San Diego School of Medicine's Center for Personalized Cancer Therapy. She will present ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Accutane, Tretinoin, Fluorouracil, Gleevec, Colorectal Cancer, Lung Cancer, Isotretinoin, Claravis, Tarceva, Xeloda, Skin Cancer, BCG, Tasigna, Revlimid, Hydroxyurea, Sprycel, Zytiga

Well Water a Suspected Cause of Bladder Cancer in New England

Posted 3 May 2016 by Drugs.com

MONDAY, May 2, 2016 – Arsenic in drinking water from private wells may explain the elevated bladder cancer risk among people in three New England states, a new study suggests. Bladder cancer rates in Maine, New Hampshire and Vermont have been about 20 percent higher than the national rate for more than 50 years, the researchers noted. They said this difference was not explained by factors such as smoking or job exposures. "Arsenic is an established cause of bladder cancer, largely based on observations from earlier studies in highly exposed populations," said senior study author Debra Silverman. She is chief of the Occupational and Environmental Epidemiology Branch of the U.S. National Cancer Institute. "However, emerging evidence suggests that low to moderate levels of exposure may also increase risk," she added in an institute news release. Many people in these states have private ... Read more

Related support groups: Cancer, Bladder Cancer, Arsenic Trioxide, Trisenox

Babies Fed Rice-Based Cereals Have Higher Arsenic Levels, Study Finds

Posted 26 Apr 2016 by Drugs.com

MONDAY, April 25, 2016 – Parents commonly give rice to their babies as a first food. Now, researchers say infants fed rice-based foods may have significantly higher "inorganic" arsenic concentrations in their urine than babies who never eat rice. The highest arsenic concentrations were found in infants who frequently ate baby rice cereal, with levels more than three times that of babies who didn't eat rice, the study reports. Babies who ate foods mixed with rice or rice-based snacks had arsenic levels nearly double those of non-rice eaters, according to the report published April 25 in the journal JAMA Pediatrics. "The arsenic in their urine increased with the number of servings of rice or rice-containing food," said lead researcher Margaret Karagas, chair of epidemiology at Dartmouth University's Geisel School of Medicine in Hanover, N.H. It's still unclear what health effects these ... Read more

Related support groups: Delivery, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Premature Labor, Postpartum Bleeding, Labor Pain, Apnea of Prematurity, Arsenic Trioxide, Cesarean Section, Prematurity/Underweight in Infancy, Trisenox, Labor and Delivery including Augmentation

FDA Suggests Limit for Arsenic in Infant Rice Cereal

Posted 2 Apr 2016 by Drugs.com

FRIDAY, April 1, 2016 – A proposed limit on "inorganic" arsenic in infant rice cereal was announced Friday by the U.S. Food and Drug Administration. Infant rice cereal is a leading source of arsenic exposure in babies, the agency said, since arsenic can find its way into rice from natural sources or from fertilizers and pesticides. The proposed limit is 100 parts per billion, which is similar to the level set by the European Commission for rice used in the production of food for infants and young children. Most infant rice cereal currently sold in the United States either meets, or is close to, the FDA's proposed limit, the agency said. "Our actions are driven by our duty to protect the public health and our careful analysis of the data and the emerging science," said Susan Mayne, director of the FDA's Center for Food Safety and Applied Nutrition. "The proposed limit is a prudent and ... Read more

Related support groups: Delivery, Labor Induction, Labor Pain, Arsenic Trioxide, Cesarean Section, Prematurity/Underweight in Infancy, Trisenox, Labor and Delivery including Augmentation

Arsenic Exposure in Womb Linked to Respiratory Risks in Babies

Posted 23 Nov 2015 by Drugs.com

MONDAY, Nov. 23, 2015 – Babies exposed to high levels of arsenic in the womb are at increased risk for infections and respiratory symptoms in their first year of life, a new study suggests. Researchers measured levels of arsenic in 412 pregnant women in New Hampshire whose homes had private wells. For a year after their babies were born, the women were surveyed every four months about the number and severity of their children's infections and respiratory symptoms, such as wheezing. Infants exposed to arsenic in the womb had more infections that led to a doctor visit or treatment with prescription medications, the investigators found. In addition, those exposed to higher levels of arsenic in the womb tended to have more upper and lower respiratory tract infections, as well as respiratory symptoms. The study was published recently in the journal Environmental Health Perspectives. "These ... Read more

Related support groups: Infections, Delivery, Premature Labor, Respiratory Tract Disease, Labor Pain, Arsenic Trioxide, Prematurity/Underweight in Infancy, Trisenox, Labor and Delivery including Augmentation

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Femara, Lupron Depot, Gleevec, Colorectal Cancer, Lung Cancer, Renal Cell Carcinoma, Rituxan

Placenta Test Measures Babies' Exposure to Arsenic

Posted 7 Apr 2015 by Drugs.com

TUESDAY, April 7, 2015 – A pregnant woman's placenta can reliably measure exposure to the toxic metal arsenic in both the mother and her unborn baby, new research finds. "Our findings show placental arsenic concentrations reflect both maternal and fetal biomarker concentrations," said the study's lead author, Tracy Punshon, a research assistant professor of biological sciences at Dartmouth College in Hanover, N.H. Arsenic, a carcinogen, occurs naturally in soil, water and air. Previous research has shown that it crosses the placenta and may affect fetal development, according to background notes with the study. Contaminated well water is one source of arsenic exposure. For this study, researchers compared arsenic concentrations detected in placental samples of 652 women with urine samples taken during pregnancy and post-delivery toenail clippings from mother and child. They also ... Read more

Related support groups: Arsenic Trioxide, Trisenox, Fetal Maturation

Mountain Dwellers in Argentina Have Adapted to High Arsenic Levels

Posted 13 Mar 2015 by Drugs.com

FRIDAY, March 13, 2015 – A new study appears to offer the first evidence of people adapting to tolerate the toxic chemical arsenic. Arsenic – the killer used by many murder mystery villains – is most toxic to young children and people in their prime reproductive years. The ability to metabolize arsenic quickly may been the difference between life and death in ancient times, said study leader Karin Broberg, a professor at the Karolinska Institute and Uppsala University in Sweden, and colleagues. The research included 124 women living high up in the Andes mountains of Argentina in an area where arsenic in the volcanic bedrock is released into the groundwater. For thousands of years, people in the region have been exposed to high levels of arsenic. Urine tests showed the women were able to metabolize arsenic. Genetic tests showed they had higher-than-normal rates of variants of a gene ... Read more

Related support groups: Arsenic Poisoning, Arsenic Trioxide, Trisenox

Arsenic in Well Water Can Raise Level in Baby Formula: Study

Posted 23 Feb 2015 by Drugs.com

MONDAY, Feb. 23, 2015 – The water used to mix baby formula plays the biggest role in whether formula-fed babies are exposed to increased levels of arsenic, according to a new study. Families that use well water instead of municipal water may need to check it for arsenic levels since well water is not regulated by the U.S. Environmental Protection Agency, the study authors suggested. The study also found that formula-fed infants took in more and excreted more arsenic than breast-fed babies. However, the amounts detected were low and should not be cause for concern, said study co-author Kathryn Cottingham, a biology professor at Dartmouth College in Hanover, N.H. "The most significant finding was that exposure to arsenic during early infancy in this U.S. population is quite low, regardless of feeding mode," Cottingham said. "Most of the infants, including the formula-fed infants, in our ... Read more

Related support groups: Arsenic Trioxide, Trisenox

Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study

Posted 3 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Many men on hormone therapy for prostate cancer aren't getting bone-strengthening drugs they may need, new Canadian research contends. Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. But one consequence of the treatment is weakening of the bones, which can lead to fractures. To reduce this risk, men can be given oral bisphosphonates, such as Fosamax, or an intravenous treatment once a month or once a year with similar drugs, such as Reclast. "There seems to be a clear mismatch between Canadian guidelines regarding bisphosphonate usage in men undergoing hormone therapy for prostate cancer and actual clinical practice," said lead researcher Dr. Shabbir Alibhai, a senior scientist at the University Health Network in Toronto. While the low rates of bisphosphonate prescriptions may be appropriate for patients ... Read more

Related support groups: Provera, Depo-Provera, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Fosamax, Arimidex, Tretinoin, Lupron Depot, Femara, Boniva, Isotretinoin, Alendronate, Claravis, Anastrozole, Reclast, Actonel, Evista

Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Provera, Depo-Provera, Amoxicillin, Metronidazole, Doxycycline, Cephalexin, Clindamycin, Penicillin, Methotrexate, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Accutane, Augmentin, Levaquin, Lupron, Flagyl, Keflex, Zithromax

Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia

Posted 14 Feb 2013 by Drugs.com

THURSDAY, Feb. 14 – Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life. Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found. On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago. One expert not connected to the study stressed that cancer patients need to put the findings into perspective. "It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Accutane, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Isotretinoin, Rituxan, Claravis, Votrient, Anastrozole, Tarceva

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Colorectal Cancer, Lung Cancer, Renal Cell Carcinoma, Isotretinoin

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