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Related terms: Fungal Infection, Groin, Infection, Fungal, Groin, Jock Itch, Ringworm, Groin, Tinea of the groin

FDA Medwatch Alert: Nizoral (ketoconazole) Oral Tablets: Drug Safety Communication - Prescribing for Unapproved Uses including Skin and Nail Infections Continues; Linked to Patient Death

Posted 23 May 2016 by Drugs.com

ISSUE: FDA is warning health care professionals to avoid prescribing the antifungal medicine ketoconazole oral tablets to treat skin and nail fungal infections. Use of this medication carries the risk of serious liver damage, adrenal gland problems, and harmful interactions with other medicines that outweigh its benefit in treating these conditions, which are not approved uses of the drug. FDA approved label changes for oral ketoconazole tablets in 2013 to reflect these serious risks and to remove the indications for treatment of skin and nail fungal infections. However, an FDA safety review found that oral ketoconazole continues to be prescribed for these types of conditions. Since the 2013 labeling change, one patient death has been reported to the FDA due to liver failure associated with oral ketoconazole prescribed to treat a fungal infection of the nails.  See the full Drug Safety ... Read more

Related support groups: Tinea Corporis, Ketoconazole, Onychomycosis - Toenail, Tinea Cruris, Diaper Rash, Nizoral, Cutaneous Candidiasis, Tinea Barbae, Tinea Versicolor, Onychomycosis - Fingernail, Tinea Pedis, Tinea Capitis, Onychomycosis, Chronic Mucocutaneous Candidiasis, Dermatophytosis, See also Cutaneous Fungal Infections, Cutaneous Sporotrichosis, Chromomycosis, Eumycetoma, Cutaneous Fungal Infection

Skin Infections Common in High School Wrestlers, Study Finds

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Wrestlers are much more likely to suffer skin infections than other U.S. high school athletes, new research shows. The study authors examined five years of data on skin infections among athletes in 22 high school sports. Nearly 74 percent of skin infections occurred among wrestlers, and just under 18 percent among football players, the investigators found. The actual rates of skin infections per 100,000 exposures (one athlete participating in one practice, competition or performance) were 28.5 among wrestlers and 2.3 among football players. Rates in most other sports were less than 1 per 100,000, and eight sports had none, according to the report. "Given the nature of the sport, it's not surprising that wrestlers suffer the most skin infections," study senior author Dr. Robert Dellavalle, an associate professor of dermatology at the University of Colorado ... Read more

Related support groups: Infections, Bacterial Infection, Bacterial Skin Infection, Fungal Infections, Tinea Corporis, Skin and Structure Infection, Candida Infections, Tinea Cruris, Tinea Pedis, Fungal Infection Prophylaxis, Fungal Infection Prevention

Valeant Pharmaceuticals Announces U.S. Approval Of Luzu Cream, 1%

Posted 17 Nov 2013 by Drugs.com

LAVAL, Quebec, Nov. 15, 2013 /PRNewswire/ – Valeant Pharmaceuticals International, Inc. announced today that its wholly owned subsidiary, Valeant Pharmaceuticals North America LLC, has received notice that the New Drug Application for Luzu (luliconazole) Cream, 1% has been approved by the United States Food and Drug Administration (FDA). Luzu Cream, 1% is indicated for the topical treatment of athlete's foot (interdigital tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis), caused by the organisms Trichophyton rubrum and Epidermophyton floccosum, in patients 18 years of age and older. These are very common skin diseases caused predominantly by dermatophyte fungi. "We are pleased to receive FDA approval for Luzu earlier than expected," said J. Michael Pearson, chairman and chief executive officer. "This is the first safe and effective product indicated for daily use ... Read more

Related support groups: Tinea Corporis, Tinea Cruris, Tinea Pedis

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