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Thrombotic Thrombocytopenic Purpura News
Related terms: TTP
Posted 24 Aug 2015 by Drugs.com
MONDAY, Aug. 24, 2015 – U.S. Food and Drug Administration approval of the drug Promacta (eltrombopag) has been expanded to include children one year and older with a rare blood disorder called chronic immune thrombocytopenic purpura (ITP). ITP is characterized by a low blood platelet count. Promacta is now approved for the disorder among children who have had unsatisfactory results with other drugs, or with surgery to remove the spleen, the agency said in a news release. Platelets help blood clot, and people with ITP can develop bleeding under the skin or in mucous membranes such as the mouth. Once-daily Promacta is designed to help increase platelet production, the FDA said. The drug, available in pill or powder form, was clinically evaluated in a trial involving 159 people. Some 62 percent of those who took Promacta saw an improvement in platelet count, compared with 32 percent among ... Read more
Posted 10 Jan 2013 by Drugs.com
THURSDAY, Jan. 10 – Tennessee health officials report cases of a rare blood-clotting problem among people who injected the painkiller Opana ER (extended release) after crushing pills meant to be taken by mouth. Thrombotic thrombocytopenic purpura (TTP) is a disorder that causes blood clots to form in small blood vessels around the body and is usually seen in about one in 100,000 people. From August to October, however, there were 15 cases seen in Tennessee. All were associated with intravenous drug abuse, with 14 specifically related to Opana ER. "I don't think anybody has a figure for the percentage of people who are crushing these drugs to inject them; nobody really knows how commonly people do that," said Dr. Leonard Paulozzi, a medical epidemiologist at the U.S. Centers for Disease Control and Prevention. There are, however, many reports of people crushing these pills to make them ... Read more
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