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Temozolomide News

Childhood Chemo May Have Lasting Effects on Memory

Posted 6 days ago by Drugs.com

TUESDAY, June 20, 2017 – Childhood cancer survivors who had chemotherapy may have certain types of thinking and memory problems as young adults, a small study suggests. Belgian researchers assessed 31 young adults who had undergone chemotherapy. They were at an average age of slightly over 6 when they had the treatment. The researchers compared them with a control group of young adults who hadn't received chemotherapy. Both groups had similar scores on tests of long-term memory and ability to concentrate. Those are skills that developed before the cancer survivors underwent chemotherapy, the researchers said. But compared to the control group, the cancer survivors had poorer thinking flexibility and short-term memory. These skills develop at a later age, the researchers explained. "Tests that require quick switching between tasks or remembering new information for a short amount of ... Read more

Related support groups: Cancer, Methotrexate, Leukemia, Fluorouracil, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Capecitabine, Dacogen, Temodar, Bendamustine, Cyclophosphamide, Oxaliplatin, Gemzar, Treanda, Gemcitabine

Publicly Funded Cancer Trials Gained Americans 3 Million More Years

Posted 20 days ago by Drugs.com

TUESDAY, June 6, 2017 – Public-funded trials have significantly extended the lives of people diagnosed with cancer, according to new research. SWOG, the clinical trials network funded by the U.S. National Cancer Institute (NCI), has involved more than 200,000 patient volunteers. These trials have led to approval of 14 new cancer drugs and more than 100 changes to cancer care standards. All told, the clinical trials studied extended life by 3.34 million years, the study found. SWOG estimates the dollar return on investment from federal funding at $125 for each year of life gained. "A lot of people with cancer have lived longer because of the therapies tested in our publicly funded trials," study leader Joseph Unger said in a SWOG news release. He is an assistant member of the Fred Hutchinson Cancer Research Center's Cancer Prevention Program in Seattle. "At the same time, the cost of ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Fluorouracil, Tretinoin, Lupron Depot, Femara, Lung Cancer, Colorectal Cancer, Gleevec, Rituxan, Isotretinoin

Seniors With Brain Cancer May Have Better Treatment Option

Posted 15 Mar 2017 by Drugs.com

WEDNESDAY, March 15, 2017 – Combined chemotherapy and radiation treatment appears to extend the lives of older patients with brain cancer, new research finds. The study involved more than 560 older patients with glioblastoma, the most common malignant brain cancer in adults. The average age of disease onset is 65 and there is no cure, according to the study. On average, patients who received the chemotherapy pill temozolomide plus a short course of radiation therapy survived two months longer than those who underwent radiation alone, an international team of researchers found. And, many patients in the combination treatment group survived nearly 14 months – about twice that compared to those who received radiation alone, the researchers reported. "Everyone benefited to a varying degree," said co-principal investigator Dr. Normand Laperriere. "There has been no clear standard of care ... Read more

Related support groups: Cancer, Brain Tumor, Temodar, Glioblastoma Multiforme, Diagnosis and Investigation, Malignant Glioma, Temozolomide

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Lung Cancer, Gleevec, Colorectal Cancer, Rituxan, Isotretinoin, Votrient

HIV Patients Less Likely to Get Treatment for Cancer: Study

Posted 17 May 2016 by Drugs.com

TUESDAY, May 17, 2016 – While powerful HIV medications are granting longer lives to many people infected with the virus, a new U.S. study shows these same patients are less likely to get treatment for cancer if it develops. It's not clear why the difference exists. It could reflect the decisions of physicians, patients or both. Whatever the case, the finding confirms that the gap persists even when patients have private insurance or are otherwise healthy, the study authors said. Previous research has suggested that "people with well-controlled HIV infection should be treated similarly to patients without HIV," said study author Dr. Gita Suneja. However, "even looking at cancer patients with private health insurance only, we saw that those with HIV infection were less likely to receive cancer treatment for many common cancer types," said Suneja. She is an assistant professor of ... Read more

Related support groups: Cancer, Methotrexate, HIV Infection, Fluorouracil, Lung Cancer, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Capecitabine, Dacogen, Temodar, Bendamustine, Cyclophosphamide, Oxaliplatin, Gemzar, Treanda

Could Talk Therapy Ease Chemo-Related Memory Issues?

Posted 2 May 2016 by Drugs.com

MONDAY, May 2, 2016 – A type of psychotherapy might help cancer survivors deal with the long-term thinking problems some experience after chemotherapy, researchers say. It's estimated that about half of those who undergo chemotherapy for cancer develop what's often called "chemo brain." For instance, they may have trouble following conversations or remembering the steps in a project, according to background notes with the new study. Although usually mild, these changes can affect quality of life, job performance and relationships, said the researchers from the Eastern Maine Medical Center and Lafayette Family Cancer Center in Bangor, Maine. The researchers developed a cognitive-behavioral therapy (CBT) program called Memory and Attention Adaptation Training to help cancer survivors prevent or manage these memory problems. Their study involved 47 breast cancer survivors who underwent ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Prostate Cancer, Fluorouracil, Lung Cancer, Colorectal Cancer, Gleevec, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Brain Tumor, Breast Cancer, Metastatic, Melanoma, Pancreatic Cancer, Skin Cancer, Xeloda, Nausea/Vomiting - Chemotherapy Induced, Tasigna, Ovarian Cancer, Endometrial Cancer

Fewer Childhood Cancer Survivors Dying From 'Late' Effects

Posted 13 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 13, 2016 – Fewer childhood cancer survivors are dying years later from lingering effects of the treatment that conquered their cancer, a new study finds. Experts called the report, published in the Jan. 14 issue of the New England Journal of Medicine, "very good news." "The findings substantiate what experts in the field have hoped would be true," said lead researcher Dr. Gregory Armstrong, of St. Jude Children's Research Hospital, in Memphis, Tenn. Survival rates from many childhood cancers are high, but survivors still face what doctors call "late effects" – health problems that develop months to years after the cancer treatment has ended. Among U.S. children who survived cancer back in the 1970s and '80s, 18 percent died within the next 25 years, Armstrong said. Sometimes, the initial cancer comes back. Often though, the health issues are related to the very ... Read more

Related support groups: Cancer, Methotrexate, Fluorouracil, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Capecitabine, Dacogen, Oxaliplatin, Cyclophosphamide, Temodar, Bendamustine, Gemcitabine, Treanda, Gemzar, Hodgkin's Lymphoma

Childhood Cancer Treatment May Raise Adult Heart Disease Risk

Posted 5 Jan 2016 by Drugs.com

MONDAY, Jan. 4, 2016 – Children who survive cancer may face a higher risk of heart disease as adults, new research suggests. The lingering effects of the treatments that saved their lives as children may trigger the development of heart abnormalities that might not cause apparent symptoms, the researchers explained. The investigators found that heart disease appears to affect between 3 percent and 24 percent of pediatric cancer survivors by the time they reach their 30s. Those figures rose to between 10 and 37 percent among patients 40 and older, the study found. However, while the study revealed a link between childhood cancer treatment and later heart disease, it didn't prove cause-and-effect. "The prevalence of these cardiac findings might be expected in an older adult population, but not necessarily in this young a population," said study lead author Dr. Daniel Mulrooney. ... Read more

Related support groups: Cancer, Heart Disease, Methotrexate, Fluorouracil, Cardiac Arrhythmia, Xeloda, Cardiomyopathy, Left Ventricular Dysfunction, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Dacogen, Capecitabine, Temodar, Bendamustine, Cyclophosphamide, Oxaliplatin

Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Researchers say they're zeroing in on factors that may increase the risk of leukemia after breast cancer treatment. The findings are a step forward in determining ways to prevent this complication in breast cancer survivors. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said. The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. "The findings justify a long-term, follow-up study of women with and without inherited breast cancer gene mutations who are ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Leukemia, Arimidex, Lupron Depot, Femara, Anastrozole, Breast Cancer, Metastatic, Letrozole, Zoladex, Evista, Megestrol, Megace, Herceptin, Aromasin, Exemestane

Optune Device Approved for Newly Diagnosed Brain Cancer

Posted 6 Oct 2015 by Drugs.com

TUESDAY, Oct. 6, 2015 – The U.S. Food and Drug Administration on Monday expanded its approval for the Optune device to include newly diagnosed glioblastoma multiforme, an aggressive brain cancer. Optune involves placing electrodes on the surface of the scalp to deliver low-intensity pulses called "tumor treatment fields," which are designed to damage growing tumor cells, the agency said in a news release. The portable device, powered by battery or plugged into a common electric outlet, can be used at home or work. It's been newly sanctioned to treat just-diagnosed patients, in combination with the chemotherapy drug temozolomide. Clinical studies of the device for this purpose showed people treated with the Optune/drug combination lived an average of three months longer than those treated with the drug alone. "Patients newly diagnosed with this challenging and aggressive form of brain ... Read more

Related support groups: Glioblastoma Multiforme, Temodar, Temozolomide

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Fluorouracil, Tretinoin, Lupron Depot, Femara, Lung Cancer, Gleevec, Colorectal Cancer, Rituxan, Renal Cell Carcinoma

Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Provera, Depo-Provera, Amoxicillin, Metronidazole, Doxycycline, Clindamycin, Cephalexin, Azithromycin, Penicillin, Bactrim, Methotrexate, Cipro, Ciprofloxacin, Accutane, Levaquin, Augmentin, Flagyl, Lupron, Keflex, Medroxyprogesterone

Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia

Posted 14 Feb 2013 by Drugs.com

THURSDAY, Feb. 14 – Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life. Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found. On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago. One expert not connected to the study stressed that cancer patients need to put the findings into perspective. "It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Rituxan, Isotretinoin, Votrient, Claravis, Anastrozole, Letrozole

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Lung Cancer, Colorectal Cancer, Gleevec, Rituxan, Renal Cell Carcinoma

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