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Viagra, Aliskiren Not Helpful for Heart Failure After All: Studies

Posted 11 Mar 2013 by Drugs.com

MONDAY, March 11 – Although small studies have suggested Viagra and the blood pressure medication aliskiren could be wonder drugs against heart failure, neither drug produced any beneficial effects against this condition in recent multicenter trials. Viagra (sildenafil) is used to treat erectile dysfunction and some forms of pulmonary arterial hypertension, and scientists hoped it would help patients with so-called diastolic heart failure – a type of heart failure in which the heart's lower chambers stiffen and cannot fully relax and fill between beats. "The results of our study were surprising and disappointing," said the Viagra study lead author, Dr. Margaret Redfield, professor of medicine at the Mayo Clinic in Rochester, Minn. "We were hoping to find something that would help these patients, as there are currently few options for treatment," Redfield said. Meanwhile, aliskiren ... Read more

Related support groups: Viagra, Heart Failure, Congestive Heart Failure, Sildenafil, Tekturna, Revatio, Aliskiren

FDA Medwatch Alert: Aliskiren-containing Medications: Drug Safety Comunication - New Warning and Contraindication

Posted 23 Apr 2012 by Drugs.com

including: Amturnide (aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide) Tekturna (aliskiren hemifumarate) Tekturna HCT (aliskiren hemifumarate and hydrochlorothiazide) Tekamlo (aliskiren hemifumarate and amlodipine besylate) Valturna (aliskiren hemifumarate and valsartan). Valturna will no longer be marketed after July 2012   [Posted 04/20/2012] ISSUE: FDA notified healthcare professionals of possible risks when using blood pressure medicines containing aliskiren with other drugs called angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in patients with diabetes or kidney (renal) impairment. These drug combinations should not be used (are contraindicated) in patients with diabetes. In addition, avoid use of aliskiren with ARBs or ACEIs in patients with moderate to severe renal impairment (i.e., where glomerular filtration ... Read more

Related support groups: High Blood Pressure, Hypertension, Tekturna, Valturna, Aliskiren, Tekturna HCT, Amturnide, Tekamlo, Aliskiren/amlodipine/hydrochlorothiazide, Aliskiren/Hydrochlorothiazide, Aliskiren/valsartan, Aliskiren/amlodipine

Taking Blood Pressure Meds at Bedtime May Be Better

Posted 24 Oct 2011 by Drugs.com

MONDAY, Oct. 24 – For the millions of Americans on blood pressure-lowering drugs, a new study suggests that taking the pills at bedtime may be best. It was known that taking blood pressure medications at different times of the day can affect patients' blood pressure patterns, but the impact on health wasn't known. The new Spanish study included 661 patients with chronic kidney disease and hypertension. Half of them took their prescribed blood pressure-lowering drugs at bedtime and half took their medications first thing in the morning. After an average follow-up of 5.4 years, the researchers found that patients who took at least one blood pressure-lowering drug at bedtime had better control of their blood pressure and were about one-third as likely to suffer a heart-related event such as heart attack, heart failure or stroke. The team at the University of Vigo also found that ... Read more

Related support groups: High Blood Pressure, Lisinopril, Hypertension, Losartan, Benicar, Diovan, Ramipril, Cozaar, Micardis, Valsartan, Enalapril, Benazepril, Avapro, Atacand, Irbesartan, Perindopril, Telmisartan, Candesartan, Tekturna, Quinapril

Accidental Medication Poisonings in Kids on the Rise

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more

Related support groups: Xanax, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, OxyContin, Klonopin, Vicodin, Lisinopril, Norco, Fentanyl, Clonazepam, Morphine, Ativan, Ambien, Valium, Codeine, Metoprolol, Lortab

Novartis Gains FDA Approval for Amturnide, a Triple-Combination Pill to Treat High Blood Pressure in Patients Uncontrolled on Two Medications

Posted 29 Dec 2010 by Drugs.com

EAST HANOVER, N.J., December 22, 2010, 2010 /PRNewswire/ – Today Novartis announced that the US Food and Drug Administration (FDA) approved Amturnide (aliskiren, amlodipine and hydrochlorothiazide) tablets for the treatment of high blood pressure. Amturnide combines the only approved direct renin inhibitor worldwide, Tekturna (aliskiren), with the widely used calcium channel blocker amlodipine and the diuretic hydrochlorothiazide (HCTZ). The FDA approval was based on data from a double-blind, active controlled study, which showed that Amturnide provided significantly greater reductions in blood pressure compared to all dual combinations of its components. Amturnide is approved for patients whose blood pressure is not adequately controlled with any two of its individual components and is not indicated as initial therapy for high blood pressure. Amturnide is only the third high blood ... Read more

Related support groups: Hypertension, Tekturna, Aliskiren, Tekturna HCT

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