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Systemic Lupus Erythematosus News

Related terms: Disseminated Lupus Erythematosus, Lupus, SLE

Lupus a Tough Disease to Spot, Treat

Posted 30 May 2016 by Drugs.com

MONDAY, May 30, 2016 – Lupus is difficult to diagnose and treat, but scientists are working to learn more about its genetic causes and to develop better treatments. The autoimmune disease affects between 300,000 and 1.5 million people in the United States, and as many as 24,000 are diagnosed with lupus each year, according to the U.S. Food and Drug Administration. "With treatment, the disease may quiet down, but it also may relapse eventually. Although it may be controlled with medications, once you get it, you will always have it," Dr. Sarah Yim, a rheumatologist at the FDA, said in an agency news release. "Technologies have been developed in recent years that can make our medicines more targeted, to address the specific molecule or molecules in the immune system that may be causing the problem," Yim added. The disease often begins between the ages of 15 and 44, and 10 times more ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Diagnosis and Investigation

Study Suggests Causes for Lupus' Impact on Immune System

Posted 8 Mar 2016 by Drugs.com

TUESDAY, March 8, 2016 – Scientists have found new clues that help explain what's going wrong in the immune systems of people with lupus – insight they hope will lead to new therapies, or help guide current treatment choices. Lupus has several forms, but the most common is systemic lupus erythematosus (SLE). In SLE, the immune system mistakenly produces antibodies against the body's own tissue. The onslaught can have widespread effects, damaging the skin, joints, heart, lungs, kidneys and brain, according to the Lupus Foundation of America. The disease mostly strikes women, usually starting in their 20s or 30s, the foundation says. In the new study, the researchers found evidence that in people with lupus, some of the immune system's "B cells" mature the wrong way – so that they promote inflammation instead of fighting it. The findings, published online March 8 in the journal ... Read more

Related support groups: Systemic Lupus Erythematosus, Plaquenil, Hydroxychloroquine, Rituxan, Prograf, Rituximab, Tacrolimus, Lupus Erythematosus, Cytoxan, Protopic, Cyclophosphamide, Envarsus XR, Neosar, Plaquenil Sulfate, Hecoria, Cytoxan Lyophilized, Quineprox, Astagraf XL

Blood Tests May Predict Pregnancy Risks for Women With Lupus

Posted 29 Sep 2015 by Drugs.com

TUESDAY, Sept. 29, 2015 – Blood tests may identify women with lupus who are at high risk for complications during pregnancy, according to a new study. Lupus is an immune system disorder known to increase the chances of pregnancy problems such as preeclampsia and miscarriage. This new research found that monitoring for certain "biomarkers" – or indicators – in the blood of lupus patients during early pregnancy can identify those who are likely to have normal pregnancies and those who are at risk for problems, the study's authors said. The researchers analyzed data from 497 pregnant women with lupus and 207 pregnant women without the disease. They were checked every month of pregnancy. The study found that biomarkers called circulating angiogenic factors – which regulate development of the placenta and influence the health of blood vessels in the mother – can be assessed early in ... Read more

Related support groups: Systemic Lupus Erythematosus, Delivery, Lupus Erythematosus, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Premature Labor, Toxemia of pregnancy, Labor Pain, Apnea of Prematurity, Cesarean Section, Prematurity/Underweight in Infancy, Labor and Delivery including Augmentation

Pregnancy Results Good for Women With Controlled Lupus: Study

Posted 22 Jun 2015 by Drugs.com

MONDAY, June 22, 2015 – Not long ago, women with lupus were often told pregnancy was too risky. But new research confirms that when the disease is under control, women usually have healthy pregnancies and babies. The study, of 385 pregnant women with lupus, found that 81 percent gave birth to a full-term, normal-weight baby. It's not always an easy road, though, the researchers found. And some women – including those with high blood pressure and symptom flare-ups during pregnancy – had higher risks of complications, including pregnancy loss and preterm delivery. Black and Hispanic women also faced greater risks than white women, for reasons that are not fully clear, experts added. The study, published in the June 23 online edition of Annals of Internal Medicine, reinforces what many doctors are already telling women with lupus: If you plan for pregnancy and get your symptoms under ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Vitamin/Mineral Supplementation during Pregnancy/Lactation

Many Women Unaware of Female-Specific Stroke Symptoms

Posted 7 May 2015 by Drugs.com

WEDNESDAY, May 6, 2015 – Stroke is the third leading cause of death in women, but many are unaware of warning signs and symptoms that are unique to females, a new study says. Of 1,000 women surveyed, only one in 10 was aware that hiccups that occur with unusual chest pain is an early warning sign of stroke in women, said researchers from Ohio State University Wexner Medical Center, in Columbus. Although men and women share some risk factors for stroke – such as smoking, being sedentary and having high blood pressure – others are specific to women, the researchers explained. But only 11 percent of women polled knew that pregnancy, lupus, migraine headaches, birth-control pills and hormone replacement therapy increase their stroke risk, the study found. "I think we have a ways to go when it comes to educating women about stroke and their unique risk factors," Dr. Diana Greene-Chandos, ... Read more

Related support groups: Birth Control, Contraception, Plan B, Migraine, Mirena, Sprintec, NuvaRing, Provera, Implanon, Nexplanon, Depo-Provera, Tri-Sprintec, Ortho Tri-Cyclen, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Ortho Evra, Plan B One-Step, Ischemic Stroke, TriNessa

Mercury in Seafood May Raise Risk of Autoimmune Diseases in Women: Study

Posted 10 Feb 2015 by Drugs.com

TUESDAY, Feb. 10, 2015 – The mercury found in some seafood may be linked to autoimmune disorders among women of childbearing age, new research suggests. Autoimmune diseases develop when the body's immune response goes awry and starts to attack healthy cells. Such diseases include lupus, rheumatoid arthritis, multiple sclerosis, inflammatory bowel disease and "Sjogren's syndrome." All told, these diseases affect roughly 50 million Americans, most of whom are women, the University of Michigan researchers said. "We don't have a very good sense of why people develop autoimmune disorders," study author Emily Somers said in a university news release. "A large number of cases are not explained by genetics," she added, "so we believe studying environmental factors will help us understand why autoimmunity happens and how we may be able to intervene to improve health outcomes. In our study, ... Read more

Related support groups: Rheumatoid Arthritis, Multiple Sclerosis, Systemic Lupus Erythematosus, Autoimmune Disorders, Inflammatory Bowel Disease, Sjogren's Syndrome, Lupus Erythematosus, Mercury Poisoning

Lupus Death Rates Vary by Race, Ethnicity, Study Finds

Posted 15 Jan 2015 by Drugs.com

THURSDAY, Jan. 15, 2015 – Asian and Hispanic lupus patients in the United States have lower death rates than whites, blacks or Native Americans with the disease, a new study reveals. Lupus is an autoimmune disease that causes joint and organ damage. Autoimmune disorders mean the body's immune system attacks healthy body tissue by mistake, according to the U.S. National Library of Medicine. "While previous research has examined racial differences among lupus patients, the studies have primarily been based at academic research centers," said lead author Dr. Jose Gomez-Puerta, of Brigham and Women's Hospital in Boston. "Our study investigates the variation in death rates due to lupus among different ethnic groups in a general clinical setting." Researchers reviewed Medicaid claims filed by more than 42,200 lupus patients, aged 18 to 65, between 2000 and 2006. Of those patients, nearly ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Certain Symptoms Can Delay Lupus Diagnosis, Researchers Report

Posted 20 Aug 2014 by Drugs.com

TUESDAY, Aug. 19, 2014 – Lupus and other rheumatic diseases can cause neurological symptoms such as headaches and seizures, which can delay a correct diagnosis for months, a new report says. Treatments for rheumatic diseases can also cause these types of symptoms, according to neurologists at Loyola University Medical Center in Maywood, Ill. Rheumatic disorders include autoimmune and inflammatory diseases of the joints and soft tissues, such as lupus, systemic vasculitis and ankylosing spondylitis. "Rheumatic disorders presenting as neurological syndromes may pose diagnostic challenges," study senior author Dr. Sean Ruland, an associate professor in the neurology department, and colleagues said in a medical center news release. The researchers noted that more than half of lupus patients suffer headaches, and one-third have migraines. Up to 20 percent have seizures, one-third have ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Lupus Patients Face High Rehospitalization Rates

Posted 11 Aug 2014 by Drugs.com

MONDAY, Aug. 11, 2014 – One in six hospitalized lupus patients requires readmission to the hospital within a month after discharge, according to a new study. While patients' disease severity contributed to readmission rates, other population differences suggest hospitals might be able to reduce rehospitalizations through better discharge plans and by addressing disparities in health care, said Dr. Jinoos Yazdany, lead researcher and associate professor of medicine at the University of California, San Francisco. Lupus is a disease in which the immune system attacks the body. Although researchers don't understand all of its causes, there is a genetic component to the disease, Yazdany said. Drugs that suppress the immune system can help control lupus but often with bad side effects. Lupus afflicts approximately 10 times more women than men and disproportionately affects racial and ethnic ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Groundbreaking Partnership Formed to Develop New Treatments

Posted 4 Feb 2014 by Drugs.com

TUESDAY, Feb. 4, 2014 – In a first-of-its-kind initiative, the U.S. National Institutes of Health has partnered with 10 drug companies and several nonprofit groups to speed development of biological ways of diagnosing and treating common chronic diseases. The first diseases targeted by the Accelerating Medicines Partnership are Alzheimer's, type 2 diabetes and two autoimmune disorders, rheumatoid arthritis and lupus. The partnership will invest more than $230 million over five years on these initial projects. The data and analyses that result will be made available to all biomedical researchers, the NIH said. "Patients and their caregivers are relying on science to find better and faster ways to detect and treat disease and improve their quality of life," NIH director Dr. Francis Collins said in an agency news release. "Currently, we are investing a great deal of money and time in ... Read more

Related support groups: Diabetes, Type 2, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Alzheimer's Disease, Lupus Erythematosus, Autoimmune Hepatitis

Lupus More Likely to Affect Young, Black Women, Study Finds

Posted 29 Oct 2013 by Drugs.com

TUESDAY, Oct. 29 – Young, black women are at higher risk for lupus and suffer more life-threatening complications than white women, a new study says. Lupus is an autoimmune disease that causes symptoms such as fatigue, fever, rashes and joint pain. It can lead to serious organ damage, and occurs more often in women than in men. For the new study, University of Michigan researchers analyzed data from about 2.4 million people in the southeastern part of the state and found that lupus affected one in 537 black women, compared with one in 1,153 white women. Black women were more likely to be diagnosed with lupus at a younger age and during childbearing years, the researchers found. Along with developing lupus earlier in life, black women with the disease also had higher rates of serious health complications, such as kidney failure and neurological problems, according to the study, which ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Headaches Accompanying Lupus Often Not Disease-Related, Study Finds

Posted 28 Oct 2013 by Drugs.com

MONDAY, Oct. 28 – Headaches are common in people with lupus, but are not linked to disease activity, according to a new study. Researchers reviewed records for more than 1,700 people with lupus, an autoimmune disease that can damage skin, joints and organs, and looked at the headaches they experienced over a number of years. The investigators found that 18 percent of the patients had headaches at the time of diagnosis, but that proportion increased to 58 percent after 10 years. Headaches were linked to a lower health-related quality of life, but were independent of treatment specific to lupus and were not associated with disease activity or lupus medications such as steroids, antimalaria drugs, and immune system-suppressing drugs, according to the study published Oct. 28 in the journal Arthritis & Rheumatism. "While lupus patients with headaches reported lower quality of life, the ... Read more

Related support groups: Headache, Systemic Lupus Erythematosus, Lupus Erythematosus

Moms With Lupus More Likely to Have Children With Autism, Study Suggests

Posted 28 Oct 2013 by Drugs.com

SATURDAY, Oct. 26 – Women with lupus are twice as likely to have a child with autism compared to mothers without the autoimmune disease, new, preliminary research finds. However, the overall risk is still low and the findings won't change the management of women with lupus, said one expert. "I wouldn't tell my lupus patients not to get pregnant," Dr. Yousaf Ali, acting chief of rheumatology at Mount Sinai Hospital in New York City. The study was undertaken to follow up on earlier, small reports that found that women with systemic lupus erythematosus (SLE) – the most common form of the disease – may have an excess risk of having children with an autism spectrum disorder, said lead investigator Dr. Evelyne Vinet, an assistant professor in the rheumatology department at McGill University Health Center in Montreal. "We identified all women with systemic lupus erythematosus in a Quebec ... Read more

Related support groups: Systemic Lupus Erythematosus, Autism, Lupus Erythematosus

Women With Lupus Seem at Higher Risk for Hip Fractures

Posted 4 Jul 2013 by Drugs.com

THURSDAY, July 4 – Women with lupus – the autoimmune disease that can damage skin, joints and organs – also are at higher risk of a hip fracture known as a cervical fracture, new research from Taiwan suggests. Dr. Shu-Hung Wang, of the Taipei Veterans General Hospital, and his colleagues evaluated nearly 15,000 adults – 90 percent of them women – who had lupus. They followed them for an average of six years. During that time, 75 suffered a hip fracture. Of those, 57 were cervical fractures of the hip; the other 18 were trochanteric fractures of the hip. "Anatomically, cervical hip fractures involve the [uppermost area of the thighbone]," said Dr. Shu-Hung Wang, a rheumatology fellow at the hospital and a co-author of the study. "Trochanteric hip fracture occurs between the lesser and greater trochanters." Trochanters are the bony prominences near the end of the thighbone. The ... Read more

Related support groups: Systemic Lupus Erythematosus, Fracture, bone, Lupus Erythematosus, Prevention of Fractures

No Evidence That Lupus Drugs Lead to Cancer, Says Study

Posted 4 Feb 2013 by Drugs.com

MONDAY, Feb. 4 – Drugs used to treat the autoimmune disease lupus do not significantly increase patients' risk of the blood cancer lymphoma, a new study says. The findings should help reduce widely held fears about a link between lupus medication and lymphoma, said the researchers at McGill University in Montreal. In people with systemic lupus erythematosus (SLE), the immune system attacks healthy tissue such as the skin, joints, kidneys and the brain. Medications to suppress the immune system are used to treat lupus, but previous research has suggested that this may put patients at increased risk for lymphoma. Because of fears about developing cancer, some lupus patients are reluctant to take their medication, and others stop taking it. This international study included 75 lupus patients who had lymphoma and nearly 5,000 cancer-free lupus patients. Researchers looked at most of the ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Cytoxan, Cyclophosphamide, Neosar, Cytoxan Lyophilized

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