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Systemic Lupus Erythematosus News

Related terms: Disseminated Lupus Erythematosus, Lupus, SLE

Could Fish Oil, Vitamin D Help Ease Lupus?

Posted 13 days ago by Drugs.com

THURSDAY, Nov. 9, 2017 – People with lupus may fare better if they have enough vitamin D and omega-3 fats in their diet, preliminary research suggests. In separate studies, researchers linked the two nutrients – or lack thereof – to higher risks of certain lupus symptoms and complications. In one, lupus patients with low blood levels of vitamin D faced a higher risk of kidney damage than those with sufficient levels. In the other, people who ate more omega-3 fats – mainly found in oily fish – tended to have less severe symptom flare-ups and better sleep quality. Neither study actually proves that the nutrients deserve the credit, said Dr. Stacy Ardoin, a member of the Lupus Foundation of America's Medical-Scientific Advisory Council. To do that, she explained, researchers need to run trials where they actually test the effects of vitamin D or omega-3. But it's "encouraging" to see ... Read more

Related support groups: Systemic Lupus Erythematosus, Dietary Supplementation, Fish Oil, Lovaza, Lupus Erythematosus, Omega-3, Dietary Fiber Supplementation, Omega 3-6-9 Complex, EPA Fish Oil, Omacor, Animi-3, Restora, Omega-3 Polyunsaturated Fatty Acids, Sea-Omega, Vascazen, Doxycycline/Omega-3 Polyunsaturated Fatty Acids, Ovega-3 Vegetarian, Sea-Omega 70, Epanova, Divista

Exercise May Stem Kidney Damage in Lupus Patients

Posted 19 Sep 2017 by Drugs.com

TUESDAY, Sept. 19, 2017 – Regular exercise may slow kidney damage in people with lupus while stress may prompt the opposite effect, new research suggests. The autoimmune disease causes the body to attack and damage vital organs such as the kidneys. Singer Selena Gomez put lupus in the spotlight last week when she received a kidney transplant because the disease had ravaged her own kidneys. But the new research, which included two mice trials and a slightly different human trial, offers new strategies that might help other lupus patients avoid the same fate. In the first trial, only 45 percent of mice with the disease that did moderate exercise (45 minutes of treadmill walking a day) had severe inflammatory damage to the kidneys, compared with 88 percent of those that did not exercise. In another experiment, mice with lupus that were subjected to daily stress had significant increases ... Read more

Related support groups: Anxiety and Stress, Systemic Lupus Erythematosus, Renal Failure, Chronic Kidney Disease, Lupus Erythematosus, Renal and Genitourinary Disorders

Selena Gomez's Kidney Transplant Puts Lupus Center Stage

Posted 15 Sep 2017 by Drugs.com

FRIDAY, Sept. 15, 2017 – When pop star Selena Gomez revealed Thursday that she had a kidney transplant, she put the autoimmune disease lupus in the spotlight. Lupus turns the body's immune system against itself and attacks vital organs, including the kidneys, which is why it's so devastating. But little is known about what causes the disease, and no real cure exists. Treatments can only keep it at bay. "Selena has a lot of courage to speak out about her condition and call attention to lupus," said Dr. Anca Askanase. She is clinical director of the Lupus Center at Columbia University Medical Center in New York City. Because Gomez needed a transplant at age 25, she probably developed lupus at an early age, added Askanase, who is also a spokeswoman for the Lupus Research Alliance. The superstar singer first told Billboard in 2015 that she had been diagnosed with lupus and was undergoing ... Read more

Related support groups: Smoking, Systemic Lupus Erythematosus, Renal Failure, Chronic Kidney Disease, Lupus Erythematosus, Kidney Transplant

Lupus Hits Certain Groups Harder

Posted 11 Sep 2017 by Drugs.com

MONDAY, Sept. 11, 2017 – There are significant ethnic and racial disparities in the rates of lupus in the United States, two new studies report. Researchers reviewed registries of people living in San Francisco and New York City with the autoimmune disease. They found that the prevalence of lupus was higher in San Francisco than in Manhattan – 85 people versus 62 people per every 100,000. Women had higher rates than men, and there were significant racial and ethnic differences. The prevalence of lupus was higher in Hispanics and Asians than whites, but not as high as in blacks, the studies found. The prevalence per 100,000 people was: 458 black women in California and 211 black women in New York; 178 Hispanic women in California and 138 Hispanic women in New York; and 150 Asian women in California and 91 Asian women in New York, compared to 110 white women in California and 64 white ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Diagnosis and Investigation

GSK Receives FDA Approval for a New Self-Injectable Formulation of Benlysta (belimumab) for Systemic Lupus Erythematosus

Posted 24 Jul 2017 by Drugs.com

London, UK 21 July 2017 – GSK announced today that the US Food and Drug Administration (FDA) has approved a new subcutaneous formulation of Benlysta (belimumab) for the treatment of adult patients with active, autoantibody‑positive SLE who are receiving standard therapy. Systemic Lupus Erythematosus (SLE) is the most common form of lupus, a chronic, incurable autoimmune disease producing autoantibodies that can attack almost any system in the body. The approval marks the first subcutaneous self-injection treatment option for patients with SLE. After training from their health care provider, patients will be able to administer the medicine as a once weekly injection of 200mg, from either a single-dose prefilled syringe or from a single-dose autoinjector. This is the second formulation of Benlysta to be granted approval for SLE, adding to the existing intravenous (IV) formulation, a ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Benlysta, Belimumab

Poverty Could Make Lupus Even Worse

Posted 19 May 2017 by Drugs.com

FRIDAY, May 19, 2017 – Poverty and race are tied to the health of lupus patients in the United States, according to two new studies. One study of 783 patients linked poverty to an increased risk of organ damage from the autoimmune disease. It was published in the journal Arthritis & Rheumatology. "Persistent poverty and being poor in an area of concentrated poverty seem to worsen the amount of disease damage over time, while exiting poverty may alleviate it," study author Edward Yelin said in a journal news release. Yelin is a retired adjunct professor at the University of California, San Francisco School of Medicine. "We have also shown that chronic stress associated with poverty may play an important role in why the poor experience more damage. Such stresses may include having to deal with food, housing and medical care insecurity," he explained. In lupus, the immune system attacks ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Delays in Lupus Care Seen Among Minorities, Less Educated

Posted 18 Nov 2016 by Drugs.com

FRIDAY, Nov. 18, 2016 – Delays in lupus treatment are more common among Americans who are black, Asian or are less educated, a new study finds. Lupus is a chronic autoimmune disease in which inflammation affects the skin, joints, kidneys and other organs. The disease occurs far more often in women than men, and also may have a higher prevalence among some ethnic groups, the researchers said. It also requires treatment by a specialist such as a rheumatologist or nephrologist, the study authors added. "Lupus is a complex disease requiring specialized treatment, and prompt referral to a specialist is integral in ensuring patients have the best possible outcomes," said lead study author Dr. Lisa Gaynon, a resident at California Pacific Medical Center in San Francisco. Gaynon and her colleagues looked at 196 lupus patients in California and found that 32 percent waited more than one year to ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

Researchers Pinpoint More Genes Linked to Vitiligo

Posted 12 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 12, 2016 – Researchers say they've identified more genes linked to the autoimmune disease vitiligo, which causes patches of white skin and hair. An international team of scientists pinpointed 23 new locations on the genome associated with susceptibility to vitiligo. That doubles the number of known genes connected with vitiligo, the researchers said. Vitiligo may be related to several other autoimmune diseases, including thyroid disease, pernicious anemia, rheumatoid arthritis, adult-onset type 1 diabetes, Addison's disease and lupus, the scientists said. Learning more about the causes of vitiligo could lead to treatment breakthroughs for the other conditions, the researchers said. They found links between genes involved in vitiligo and some of the other conditions. While it's unclear whether this indicates shared causes, the findings suggest promising areas for future ... Read more

Related support groups: Rheumatoid Arthritis, Thyroid Disease, Systemic Lupus Erythematosus, Diabetes, Type 1, Lupus Erythematosus, Addison's Disease, Vitiligo, Diabetes Mellitus, Diagnosis and Investigation

Lupus a Tough Disease to Spot, Treat

Posted 30 May 2016 by Drugs.com

MONDAY, May 30, 2016 – Lupus is difficult to diagnose and treat, but scientists are working to learn more about its genetic causes and to develop better treatments. The autoimmune disease affects between 300,000 and 1.5 million people in the United States, and as many as 24,000 are diagnosed with lupus each year, according to the U.S. Food and Drug Administration. "With treatment, the disease may quiet down, but it also may relapse eventually. Although it may be controlled with medications, once you get it, you will always have it," Dr. Sarah Yim, a rheumatologist at the FDA, said in an agency news release. "Technologies have been developed in recent years that can make our medicines more targeted, to address the specific molecule or molecules in the immune system that may be causing the problem," Yim added. The disease often begins between the ages of 15 and 44, and 10 times more ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Diagnosis and Investigation

Study Suggests Causes for Lupus' Impact on Immune System

Posted 8 Mar 2016 by Drugs.com

TUESDAY, March 8, 2016 – Scientists have found new clues that help explain what's going wrong in the immune systems of people with lupus – insight they hope will lead to new therapies, or help guide current treatment choices. Lupus has several forms, but the most common is systemic lupus erythematosus (SLE). In SLE, the immune system mistakenly produces antibodies against the body's own tissue. The onslaught can have widespread effects, damaging the skin, joints, heart, lungs, kidneys and brain, according to the Lupus Foundation of America. The disease mostly strikes women, usually starting in their 20s or 30s, the foundation says. In the new study, the researchers found evidence that in people with lupus, some of the immune system's "B cells" mature the wrong way – so that they promote inflammation instead of fighting it. The findings, published online March 8 in the journal ... Read more

Related support groups: Systemic Lupus Erythematosus, Plaquenil, Hydroxychloroquine, Rituxan, Prograf, Lupus Erythematosus, Rituximab, Tacrolimus, Cytoxan, Protopic, Cyclophosphamide, Neosar, Envarsus XR, Quineprox, Astagraf XL, Plaquenil Sulfate, Hecoria, Cytoxan Lyophilized

Blood Tests May Predict Pregnancy Risks for Women With Lupus

Posted 29 Sep 2015 by Drugs.com

TUESDAY, Sept. 29, 2015 – Blood tests may identify women with lupus who are at high risk for complications during pregnancy, according to a new study. Lupus is an immune system disorder known to increase the chances of pregnancy problems such as preeclampsia and miscarriage. This new research found that monitoring for certain "biomarkers" – or indicators – in the blood of lupus patients during early pregnancy can identify those who are likely to have normal pregnancies and those who are at risk for problems, the study's authors said. The researchers analyzed data from 497 pregnant women with lupus and 207 pregnant women without the disease. They were checked every month of pregnancy. The study found that biomarkers called circulating angiogenic factors – which regulate development of the placenta and influence the health of blood vessels in the mother – can be assessed early in ... Read more

Related support groups: Systemic Lupus Erythematosus, Delivery, Lupus Erythematosus, Premature Labor, Toxemia of pregnancy, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Labor Pain, Cesarean Section, Apnea of Prematurity, Prematurity/Underweight in Infancy, Labor and Delivery including Augmentation

Pregnancy Results Good for Women With Controlled Lupus: Study

Posted 22 Jun 2015 by Drugs.com

MONDAY, June 22, 2015 – Not long ago, women with lupus were often told pregnancy was too risky. But new research confirms that when the disease is under control, women usually have healthy pregnancies and babies. The study, of 385 pregnant women with lupus, found that 81 percent gave birth to a full-term, normal-weight baby. It's not always an easy road, though, the researchers found. And some women – including those with high blood pressure and symptom flare-ups during pregnancy – had higher risks of complications, including pregnancy loss and preterm delivery. Black and Hispanic women also faced greater risks than white women, for reasons that are not fully clear, experts added. The study, published in the June 23 online edition of Annals of Internal Medicine, reinforces what many doctors are already telling women with lupus: If you plan for pregnancy and get your symptoms under ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus, Vitamin/Mineral Supplementation during Pregnancy/Lactation

Many Women Unaware of Female-Specific Stroke Symptoms

Posted 7 May 2015 by Drugs.com

WEDNESDAY, May 6, 2015 – Stroke is the third leading cause of death in women, but many are unaware of warning signs and symptoms that are unique to females, a new study says. Of 1,000 women surveyed, only one in 10 was aware that hiccups that occur with unusual chest pain is an early warning sign of stroke in women, said researchers from Ohio State University Wexner Medical Center, in Columbus. Although men and women share some risk factors for stroke – such as smoking, being sedentary and having high blood pressure – others are specific to women, the researchers explained. But only 11 percent of women polled knew that pregnancy, lupus, migraine headaches, birth-control pills and hormone replacement therapy increase their stroke risk, the study found. "I think we have a ways to go when it comes to educating women about stroke and their unique risk factors," Dr. Diana Greene-Chandos, ... Read more

Related support groups: Birth Control, Plan B, Contraception, Migraine, Provera, Depo-Provera, Nexplanon, Mirena, NuvaRing, Sprintec, Implanon, Tri-Sprintec, Ortho Tri-Cyclen, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Ortho Evra, Plan B One-Step, Ischemic Stroke, Systemic Lupus Erythematosus

Mercury in Seafood May Raise Risk of Autoimmune Diseases in Women: Study

Posted 10 Feb 2015 by Drugs.com

TUESDAY, Feb. 10, 2015 – The mercury found in some seafood may be linked to autoimmune disorders among women of childbearing age, new research suggests. Autoimmune diseases develop when the body's immune response goes awry and starts to attack healthy cells. Such diseases include lupus, rheumatoid arthritis, multiple sclerosis, inflammatory bowel disease and "Sjogren's syndrome." All told, these diseases affect roughly 50 million Americans, most of whom are women, the University of Michigan researchers said. "We don't have a very good sense of why people develop autoimmune disorders," study author Emily Somers said in a university news release. "A large number of cases are not explained by genetics," she added, "so we believe studying environmental factors will help us understand why autoimmunity happens and how we may be able to intervene to improve health outcomes. In our study, ... Read more

Related support groups: Rheumatoid Arthritis, Multiple Sclerosis, Systemic Lupus Erythematosus, Autoimmune Disorders, Inflammatory Bowel Disease, Sjogren's Syndrome, Lupus Erythematosus, Mercury Poisoning

Lupus Death Rates Vary by Race, Ethnicity, Study Finds

Posted 15 Jan 2015 by Drugs.com

THURSDAY, Jan. 15, 2015 – Asian and Hispanic lupus patients in the United States have lower death rates than whites, blacks or Native Americans with the disease, a new study reveals. Lupus is an autoimmune disease that causes joint and organ damage. Autoimmune disorders mean the body's immune system attacks healthy body tissue by mistake, according to the U.S. National Library of Medicine. "While previous research has examined racial differences among lupus patients, the studies have primarily been based at academic research centers," said lead author Dr. Jose Gomez-Puerta, of Brigham and Women's Hospital in Boston. "Our study investigates the variation in death rates due to lupus among different ethnic groups in a general clinical setting." Researchers reviewed Medicaid claims filed by more than 42,200 lupus patients, aged 18 to 65, between 2000 and 2006. Of those patients, nearly ... Read more

Related support groups: Systemic Lupus Erythematosus, Lupus Erythematosus

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