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Penicillin Allergy Might Not Include Related Antibiotic

Posted 27 Feb 2010 by Drugs.com

SATURDAY, Feb. 27 – Most patients who have a history of penicillin allergy can safely take antibiotics called cephalosporins, U.S. researchers say. Cephalosporins – which are related to penicillin in their structure, uses and effects – are the most frequently prescribed class of antibiotics. "Almost all patients undergoing major surgery receive antibiotics to reduce the risk of infections. Many patients with a history of penicillin allergy don't get the cephalosporin because of a concern of possible drug reaction. They might get a second-choice antibiotic that is not quite as effective," study author Dr. James T. Li, of the Mayo Clinic in Rochester, Minn., said in a news release from the American Academy of Allergy, Asthma & Immunology. He and his colleagues conducted penicillin allergy skin tests on 178 patients who reported a history of severe allergic (anaphylactic) reaction to ... Read more

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