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Severe Psoriasis May Make Diabetes Increasingly Likely

Posted 20 Nov 2017 by Drugs.com

MONDAY, Nov. 20, 2017 – People with the skin disease psoriasis are at increased risk for type 2 diabetes, and the more severe the psoriasis, the greater their risk, a new study finds. Researchers examined data on nearly 85,000 adults in the United Kingdom, including 8,100 who had psoriasis. Compared with people who did not have psoriasis, the risk for diabetes was 21 percent higher among those with psoriasis on 2 percent or less of their body. It was 64 percent higher among those with psoriasis on more than 10 percent of their body. For every 10 percent increase in body area with psoriasis, the risk for diabetes rose another 20 percent. For instance, people with psoriasis on 20 percent of their body had a nearly 84 percent increased risk for diabetes. And those with psoriasis on 30 percent of their body had a 104 percent increased risk, the study authors said. When applying their ... Read more

Related support groups: Diabetes, Type 2, Methotrexate, Psoriasis, Plaque Psoriasis, Tazorac, Dovonex, Soriatane, Taclonex, Acitretin, Calcipotriene, Vectical, Oxsoralen, Anthralin, Resorcinol, Enstilar, Drithocreme, Methotrexate LPF Sodium, Methoxsalen, Tazarotene, Psoriatec

Cyndi Lauper's Psoriasis Battle Shows Her 'True Colors'

Posted 25 Oct 2017 by Drugs.com

WEDNESDAY, Oct. 25, 2017 – With her pink tresses and eye-catching stage costumes, pop culture icon Cyndi Lauper was never one to hide. But that's exactly what she wanted to do when she developed psoriasis, which spread to most of her body and sapped her strength before the skin disorder was controlled. Appearing first on her scalp and later covering everything except her face, psoriasis struck Lauper in 2010 while the Grammy, Tony and Emmy award-winning singer-songwriter – famous for 1980s' hits such as "Girls Just Want to Have Fun" and "Time After Time" – was on tour. She soldiered through appearances despite crushing exhaustion and an inability to regulate her temperature, which left her zigzagging between hot and cold. "It's funny – you start wearing gloves, or this and that, hoping that [psoriasis] is invisible, but it's not. I wasn't wearing it like, 'Woo-hoo, check this out!' ... Read more

Related support groups: Skin Rash, Methotrexate, Psoriasis, Plaque Psoriasis, Tazorac, Dovonex, Soriatane, Taclonex, Acitretin, Calcipotriene, Vectical, Oxsoralen, Anthralin, Resorcinol, Enstilar, Drithocreme, Methotrexate LPF Sodium, Methoxsalen, Tazarotene, Psoriatec

Severe Psoriasis Linked to Higher Risk of Earlier Death

Posted 5 Sep 2017 by Drugs.com

TUESDAY, Sept. 5, 2017 – People with severe cases of the skin disease psoriasis appeared to have almost double the risk of dying during a four-year study than people without the condition, research suggests. But the increased death rate was only seen in those with psoriasis affecting more than 10 percent of their body surface area. For those with less-severe disease, the risk of dying early was actually less than it was for people who didn't have the skin condition. Dr. Robert Kirsner, chair of dermatology at the University of Miami Miller School of Medicine, said that over the last decade or so, doctors have learned that people with psoriasis tend to be less healthy. "They are overweight, have diabetes mellitus, smoke, drink and have high cholesterol," he said. "These factors – as well as the presence of psoriasis itself – increases their risk for vascular disease and other poor ... Read more

Related support groups: Skin Rash, Smoking, Methotrexate, Psoriasis, Smoking Cessation, Plaque Psoriasis, Diabetes Mellitus, Tazorac, Dovonex, Soriatane, Taclonex, Acitretin, Calcipotriene, Anthralin, Oxsoralen, Resorcinol, Vectical, Enstilar, Tazarotene, Drithocreme

Siliq Approved for Plaque Psoriasis

Posted 2 Mar 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – The injected drug Siliq (brodalumab) has been approved by the U.S. Food and Drug Administration to treat moderate-to-severe plaque psoriasis in adults. Siliq is approved for patients who've already failed to respond to other systemic therapies, the agency noted. The autoimmune disease – so-called because the immune system produces antibodies that attack the body's own tissues – causes thick, scaly patches of red skin. The drug is designed to inhibit the body's inflammatory response that plays a role in the development of plaque psoriasis, the FDA said in a news release. The disease occurs most often in people with a family history, usually between ages 15 and 35. Saliq was evaluated in clinical studies involving more than 4,300 people with moderate-to-severe plaque psoriasis. The most common side effects included joint pain, headache, fatigue, diarrhea, ... Read more

Related support groups: Methotrexate, Psoriasis, Plaque Psoriasis, Tazorac, Dovonex, Soriatane, Taclonex, Acitretin, Calcipotriene, Resorcinol, Oxsoralen, Enstilar, Vectical, Anthralin, Drithocreme, Methotrexate LPF Sodium, Psoriatec, Siliq, Dritho-Scalp, Methoxsalen

FDA Approves Injectable Psoriasis Drug Siliq for Tough Cases

Posted 16 Feb 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – A new drug to treat tough cases of the skin condition psoriasis has won approval from the U.S. Food and Drug Administration. Valeant Pharmaceuticals' injectable drug Siliq (brodalumab) was approved for adults with moderate-to-severe psoriasis that isn't responding to other recommended treatments. However, the drug carries a warning about increased risk for suicidal behavior. Psoriasis is characterized by raised patches of red skin and flaking. The condition usually begins between ages 15 and 35 and is thought to be an autoimmune disorder, meaning the body mistakenly attacks healthy cells. "Moderate-to-severe plaque psoriasis can cause significant skin irritation and discomfort for patients, and today's approval provides patients with another treatment option for their psoriasis," said the FDA's Dr. Julie Beitz. Beitz is director of the Office of Drug ... Read more

Related support groups: Methotrexate, Psoriasis, Plaque Psoriasis, Tazorac, Dovonex, Soriatane, Taclonex, Acitretin, Calcipotriene, Resorcinol, Oxsoralen, Enstilar, Vectical, Anthralin, Drithocreme, Methotrexate LPF Sodium, Psoriatec, Dritho-Scalp, Methoxsalen, Tazarotene

Health Tip: Acne Has Lasting Effects

Posted 15 Dec 2015 by Drugs.com

-- Acne may be most visible on the skin, but for many people, its effects are greater than just temporary blemishes. Acne can lead to these physical and emotional issues, says the American Academy of Dermatology: Developing poor self-esteem and isolation. Developing depression, which can become severe. Developing dark spots that remain after acne has cleared. These may last for months or years. Developing scars. Read more

Related support groups: Acne, Rosacea, Epiduo, Retin-A, Benzoyl Peroxide, Acne Treatment, Adapalene, Differin, Compound W, Salicylic Acid, Finacea, Aczone, Benzaclin, Duac, Duofilm, Ziana, Soriatane, Benzoyl Peroxide/Clindamycin, A/T/S, Atralin

Worse Psoriasis, Less Healthy Arteries, Study Finds

Posted 8 Oct 2015 by Drugs.com

THURSDAY, Oct. 8, 2015 – The skin disorder psoriasis appears linked with artery inflammation, raising the odds for heart disease, a new study says. "As the amount of psoriasis increases, the amount of blood vessel inflammation increases," said senior investigator Dr. Nehal Mehta, a clinical investigator with the U.S. National Heart, Lung, and Blood Institute. His team also found that even mild psoriasis may indicate an increased risk for heart attack and stroke. Just one psoriasis skin patch, or plaque, "might be biologically active, causing low-grade inflammation and starting a cascade, speeding up their blood vessel disease," Mehta said. "People really should know that psoriasis is not just a cosmetic disease," he added. However, these study findings only show an association between psoriasis and blood vessel inflammation, not a direct cause-and-effect relationship, Mehta said. His ... Read more

Related support groups: Methotrexate, Psoriasis, Inflammatory Conditions, Plaque Psoriasis, Coronary Artery Disease (CAD), Tazorac, Dovonex, Acute Coronary Syndrome, Soriatane, Taclonex, Acitretin, Calcipotriene, Resorcinol, Acute Coronary Syndrome - Prophylaxis, Anthralin, Vectical, Oxsoralen, Psoriatec, Drithocreme, Methotrexate LPF Sodium

Newer Psoriasis Drugs May Lower Heart Attack Risk for Patients

Posted 20 Aug 2012 by Drugs.com

MONDAY, Aug. 20 – People with psoriasis who take a new class of drugs known as tumor necrosis factor (TNF) inhibitors may be at a lower risk for heart attack than their counterparts who only use topical medications to treat this inflammatory skin condition, a new study shows. And patients taking older systemic medicines and phototherapy may also have a reduced heart attack risk compared to those using topical preparations, the study found. Of 8,845 study participants, about 57 percent were treated with topical therapy only, 19 percent received a TNF inhibitor for at least two months and about 24 percent were treated with other medications or phototherapy. People who were treated with TNF inhibitors had a 50 percent lower risk, and those treated with other psoriasis drugs or phototherapy had a 46 percent lower risk for heart attack, than those who used topical medications alone. The ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Humira, Psoriasis, Enbrel, Remicade, Cyclosporine, Cimzia, Simponi, Soriatane, Adalimumab, Infliximab, Neoral, Acitretin, Etanercept, Golimumab, Certolizumab, Gengraf, Methotrexate LPF Sodium, Sandimmune

Acne, Psoriasis Meds Don't Raise Fracture Risk

Posted 17 May 2010 by Drugs.com

MONDAY, May 17 – Patients who take drugs like Accutane and Soriatane for acne and psoriasis don't seem to be at higher risk of breaking bones, a new study finds, even though similar dietary supplements have been linked to fractures. Accutane and Soriatane – known generically as isotretinoin and acitretin – are similar to vitamin A, which has been linked to broken bones when taken in high doses. The drugs themselves, which are used to treat acne and psoriasis, have been connected to lower levels of bone density. In the new study, researchers at Aarhus University Hospital in Denmark studied 124,655 patients with broken bones from the year 2000. They compared them to people of the same age and sex who didn't have broken bones. The researchers found that the drugs didn't boost the risk of broken bones, even at high doses. The study appears in the May issue of the Archives of Dermatology. ... Read more

Related support groups: Accutane, Isotretinoin, Claravis, Amnesteem, Soriatane, Sotret, Acitretin, Soriatane CK

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