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Schizoaffective Disorder News

Genes Start Mutating Soon After Life Begins, Study Finds

Posted 7 days ago by Drugs.com

THURSDAY, Dec. 7, 2017 – Hundreds of minor genetic mutations start to form in the cells of an embryo soon after conception, researchers have discovered. The Yale University and Mayo Clinic scientists said that many of these mutations occur as sex cells are forming in the embryo. That means they can become part of the embryo's genome and be passed on to the next generation. "This opens up a larger perspective on human development," study author Flora Vaccarino, a neuroscience professor at Yale, said in a Yale news release. "Some of our genome does not come from our parents." These early genetic mutations are also similar to those found in cancers, according to the researchers. They said this suggests that cancers can occur as a normal byproduct of cell division. They added that their findings may provide new insight into the causes of neurodevelopmental disorders such as schizophrenia ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder, Autism, Asperger Syndrome, Diagnosis and Investigation

FDA OKs First 'Digital Pill', Abilify Mycite, That Lets Doctors Know It's Been Taken

Posted 14 Nov 2017 by Drugs.com

TUESDAY, Nov. 14, 2017 – Offering both the promise of better patient compliance with health care, but also fears of a medical "Big Brother," a newly approved "digital pill" allows physicians to track whether or not it's been ingested by patients. The U.S. Food and Drug Administration has given the nod to Abilify MyCite, for use in patients with schizophrenia, an add-on treatment for depression, and to help control episodes of either manic or "mixed" episodes for people with bipolar disorder. As explained in an FDA news release, the pill contains a sensor that communicates with a wearable patch. This patch in turn sends signals to the patients' smartphone, telling them whether or not they've taken the pill, along with the pertinent dates and times. "Patients can also permit their caregivers and physician to access the information through a web-based portal," the FDA noted – opening the ... Read more

Related support groups: Bipolar Disorder, Abilify, Schizophrenia, Mania, Schizoaffective Disorder, Aripiprazole, Abilify Maintena, Abilify Discmelt, Aristada, Abilify MyCite

'Digital Pill' Tells Doctor When Patient Takes It

Posted 14 Nov 2017 by Drugs.com

TUESDAY, Nov. 14, 2017 – The first drug designed to alert a doctor when a patient takes the medication has been approved by the U.S. Food and Drug Administration. Abilify MyCite (aripiprazole with sensor) has an embedded sensor that sends a message to a wearable patch that the medication's been taken. This allows the patient and doctor to track the medication's use via smartphone. Abilify, first approved in 2012, is now OK'd to treat schizophrenia, manic depression and bipolar disorder, the FDA said in a news release. "Being able to track ingestion of medications prescribed for mental illness may be useful for some patients," said Dr. Mitchell Mathis, director of the agency's Division of Psychiatry Products. Abilify MyCite hasn't been proven to improve patient compliance with taking medication on a prescribed schedule, the FDA stressed. And the drug shouldn't be used in an attempt to ... Read more

Related support groups: Depression, Bipolar Disorder, Abilify, Schizophrenia, Schizoaffective Disorder, Aripiprazole, Abilify Maintena, Abilify Discmelt, Aristada, Abilify MyCite

Genes May Explain Why Some Don't Respond to Bipolar Drug

Posted 8 Nov 2017 by Drugs.com

WEDNESDAY, Nov. 8, 2017 – In a finding that pulls the roots of two mental illnesses closer together, researchers say people with bipolar disorder that's resistant to the drug lithium have a high number of genes associated with schizophrenia. Since the 1950s, lithium has been widely used to treat bipolar disorder. The drug stabilizes mood swings – the highs and lows associated with the disorder – and reduces the risk of suicide. But nearly one-fourth of patients don't respond to the drug and about 30 percent have only a partial response. To learn more about why some don't respond to the treatment, researchers studied the genetics of more than 2,500 bipolar patients who were given lithium. "We found that patients clinically diagnosed with bipolar disorder who showed a poor response to lithium treatment all shared something in common: a high number of genes previously identified for ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Lithium, Schizophrenia, Mania, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Invega, Rexulti, Clozapine, Aripiprazole

Schizophrenia Affects Brain's Communication Network

Posted 18 Oct 2017 by Drugs.com

WEDNESDAY, Oct. 18, 2017 – The mental illness schizophrenia disrupts the brain's entire communication network, a new study suggests. This research disputes a theory that schizophrenia is caused by wiring problems only in certain parts of the brain. The findings could help direct future research into the disorder that affects more than 21 million people worldwide, the researchers said. "We can definitively say for the first time that schizophrenia is a disorder where white matter wiring is frayed throughout the brain," said study co-lead author Sinead Kelly, formerly a researcher at the Neuroimaging and Informatics Institute at the University of Southern California's Keck School of Medicine. The study included a review of brain scans from more than 1,900 people worldwide with schizophrenia. The researchers analyzed the "white matter" – the fatty brain tissue that enables brain cells ... Read more

Related support groups: Depression, Schizophrenia, Schizoaffective Disorder, Diagnosis and Investigation, Head Imaging

Americans More Open About Mental Health Issues, But Stigma Lingers

Posted 3 Oct 2017 by Drugs.com

TUESDAY, Oct. 3, 2017 – Americans may be more willing to talk about mental health issues these days, but misperceptions and stigmas persist, a new survey finds. The survey, of more than 3,000 U.S. adults, found that 70 percent said they feel people are more open to discussing mental health compared with a decade ago. Most respondents also said they'd want to help a family member or friend struggling with depression or other mental health conditions. On the other hand, age-old misperceptions were still common. Many people, for example, thought that mental health disorders were at least partially driven by "personal failings." "That's certainly disappointing," said Dr. Don Mordecai, director of mental health and addiction medicine services at Kaiser Permanente, in Oakland, Calif., which commissioned the poll. "These are true brain conditions," Mordecai said, "and we have to get away from ... Read more

Related support groups: Anxiety, Depression, Bipolar Disorder, Anxiety and Stress, Major Depressive Disorder, Obsessive Compulsive Disorder, Post Traumatic Stress Disorder, Schizophrenia, Paranoid Disorder, Schizoaffective Disorder, Psychiatric Disorders, Dysthymia, Severe Mood Dysregulation

Your Sociability May Hinge on 'Love Hormone'

Posted 29 Sep 2017 by Drugs.com

FRIDAY, Sept. 29, 2017 – If you like to hang out with friends, it might be due to the "love hormone" oxytocin, a new mouse study suggests. Oxytocin promotes socialization by triggering pleasurable feelings when people get together, said Stanford University researchers. "Our study reveals new insights about the brain circuitry behind social reward, the positive experience you often get when you run into an old friend or meet somebody you like," said study senior author Dr. Robert Malenka. He's associate chair of psychiatry and behavioral science at Stanford's School of Medicine. "The reward circuitry is crucial to our survival because it rewards us for doing things that have, during our evolutionary history, tended to enhance our survival, our reproduction and the survival of our resulting offspring," he explained in a university news release. For example, when you're hungry, food ... Read more

Related support groups: Anxiety, Anxiety and Stress, Social Anxiety Disorder, Schizophrenia, Schizoaffective Disorder, Autism, Asperger Syndrome

Magnetic Brain Stimulation May Quiet 'Voices' in Schizophrenia

Posted 7 Sep 2017 by Drugs.com

THURSDAY, Sept. 7, 2017 – A therapy that stimulates a region of the brain linked to language may help quiet the hallucinatory "voices" that often plague schizophrenia patients, new research suggests. A voice hallucination "seems very real for the patient, and very disturbing," explained study author Dr. Sonia Dollfus. "The voices can be felt inside or outside the brain." Dollfus is head of the mental health department with the Hospital Center University of Caen in France. Typically, the 70 percent of schizophrenia patients who experience these voices are treated with antipsychotics, she said. Unfortunately, not all patients respond, but this new treatment may be a "very promising" alternative, she added. Dollfus noted that voice hallucinations can involve just one voice or several voices, speaking intermittently or constantly. In some cases the voices – which can be adversarial or ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Haldol, Invega, Rexulti, Clozapine, Haloperidol, Aripiprazole

FDA Medwatch Alert: Paliperidone Extended-Release Tablets 3mg by Teva Pharmaceuticals: Recall - Dissolution Test Failure

Posted 19 Jun 2017 by Drugs.com

ISSUE: Teva Pharmaceuticals USA, Inc. (Teva) initiated a voluntary recall to retail-level on 05/31/2017 for one lot of Paliperidone Extended-Release Tablets, 3mg, 90 count bottles, lot 1160682A, expiration 6/2018, NDC 0591-3693-19, that was distributed under the Actavis Pharma Inc. label. In coordination with FDA, Teva is extending this recall to the consumer/user level.  This recall is being carried out due to failing test results for dissolution. Teva cannot at this time exclude the potential for additional tablets to be below specification. Taking a product for the treatment of schizophrenia and schizoaffective disorders that has failed dissolution could result in less drug being absorbed. If two or more consecutive dosing regimens are with affected product, a failure to maintain therapeutic levels could occur, which could reduce effectiveness in treating a patient’s mental and/or moo ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder, Invega, Invega Sustenna, Paliperidone, Invega Trinza

'Recovery-Oriented' Talk Therapy May Help Curb Schizophrenia

Posted 6 Jun 2017 by Drugs.com

TUESDAY, June 6, 2017 – A type of talk therapy may provide lasting benefits for schizophrenia patients, a new study suggests. This approach is called recovery-oriented cognitive therapy. The study of 60 patients found those who received this therapy showed major improvements compared to those who received standard treatment, said researcher Paul Grant and his colleagues at the University of Pennsylvania. Schizophrenia is a serious mental illness. People with low-functioning schizophrenia are often isolated and disengaged from the outside world, lacking any future goals. In recovery-oriented cognitive therapy, a therapist helps the patient identify goals – like getting a specific job, reconnecting with family, or living independently. The therapist then works with the patient to overcome challenges and prevent relapse. Study participants had schizophrenia or schizoaffective disorder. ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Haldol, Invega, Rexulti, Clozapine, Haloperidol, Aripiprazole

City Life Tough on Teens' Mental Health

Posted 23 May 2017 by Drugs.com

TUESDAY, May 23, 2017 – City life seems to take a toll on the adolescent mind, new research suggests. The study included more than 2,000 18-year-olds in England and Wales who were interviewed about psychotic experiences (such as hearing voices and feeling extremely paranoid) since age 12. The research team from King's College London and Duke University found that teens raised in large cities were over 40 percent more likely to report psychotic experiences than those who grew up in rural areas. "These findings highlight the importance of early, preventative strategies for reducing psychosis risk and suggests that adolescents living in threatening neighborhoods within cities should be made a priority," said study co-senior author Helen Fisher. She is from the Institute of Psychiatry, Psychology & Neuroscience at King's College. "If we intervene early enough – for example by offering ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder, Psychosis, Psychiatric Disorders, Drug Psychosis, Depressive Psychosis

Women Aren't Better at Reading People's Faces After All

Posted 19 May 2017 by Drugs.com

FRIDAY, May 19, 2017 – When it comes to spotting a familiar face, men are just as gifted as women, a new study suggests. The finding contradicts the widely held belief that women are better at recognizing faces and reading facial expressions than men are, the Penn State researchers said. "There has been common lore in the behavioral literature that women do better than men in many types of face-processing tasks, such as face recognition and detecting and categorizing facial expressions, although, when you look in the empirical literature, the findings are not so clear-cut," said researcher Suzy Scherf. She is an assistant professor of psychology and neuroscience. "I went into this work fully expecting to see an effect of biological sex on the part of the observer in facial recognition – and we did not find any. And we looked really hard," she added in a Penn State news release. Facial ... Read more

Related support groups: Depression, Generalized Anxiety Disorder, Bipolar Disorder, Social Anxiety Disorder, Schizophrenia, Paranoid Disorder, Schizoaffective Disorder, Psychiatric Disorders, Dysthymia, Diagnosis and Investigation

Just 1 in 5 Mentally Ill Women Gets Cervical Cancer Screenings

Posted 17 Apr 2017 by Drugs.com

MONDAY, April 17, 2017 – Cervical cancer screening rates are much lower among women with severe mental illness than among other women, a new study finds. "The results of this very large study indicate that we need to better prioritize cervical cancer screening for these high-risk women with severe mental illnesses," said study senior author Dr. Christina Mangurian. She's an associate professor of clinical psychiatry at the University of California, San Francisco. Researchers reviewed 2010-11 California Medicaid data for the study. Of the women with severe mental illness, 42 percent had some form of schizophrenia. Almost a third of the women had major depression. Nearly one in five had bipolar disorder, and the rest had anxiety or another disorder. The study showed that 20 percent of women with severe mental illness were screened for cervical cancer. But 42 percent of women in the ... Read more

Related support groups: Depression, Bipolar Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, Post Traumatic Stress Disorder, Schizophrenia, Mania, Borderline Personality Disorder, Schizoaffective Disorder, Sexual Dysfunction, SSRI Induced, Psychosis, Autism, Psychiatric Disorders, Asperger Syndrome, Neurosis, Body Dysmorphic Disorder, Dissociative Identity Disorder, Neurotic Depression, Excoriation Disorder, Dermatillomania

Infections More Common in People With Schizophrenia

Posted 4 Apr 2017 by Drugs.com

MONDAY, April 3, 2017 – People with schizophrenia may face an increased risk for serious infections, a new study suggests. "The preliminary data results suggest that individuals with schizophrenia have higher prevalence of all types of severe infections compared to the background population," study author Monika Pankiewicz-Dulacz, from the University of Southern Denmark, and colleagues wrote. "Clinicians should be aware that people with schizophrenia are the risk group for severe infections. General guidelines and suggestions regarding prevention of severe infections among schizophrenia patients are needed, and they should address a wide range of areas including hygiene, diet, activities, medications, treatment of comorbid [co-existing] conditions and vaccinations," the researchers concluded. However, the study's findings only show a link between schizophrenia and certain infections, ... Read more

Related support groups: Infections, Urinary Tract Infection, Bacterial Infection, Schizophrenia, Schizoaffective Disorder, Bacterial Skin Infection, Skin and Structure Infection, Tuberculosis, Viral Infection, Infectious Hepatitis, Wound Infection

Patients Often Reject Drug-Only Psychiatric Treatment

Posted 6 Mar 2017 by Drugs.com

MONDAY, March 6, 2017 – Mental health patients are more likely to reject treatment if it involves only drugs, a new study finds. Some experts believe talk therapy should be the first treatment option for many mental health disorders. The new finding – from a review of 186 prior studies – supports that stance, the researchers said. "Patients often desire an opportunity to talk with and work through their problems with a caring individual who might be able to help them better face their emotional experiences," said study co-author Roger Greenberg. He's a professor of psychology at the State University of New York's Upstate Medical University. Greenberg and his colleagues analyzed 186 studies of patients who sought help for mental health conditions. Overall, the average treatment refusal rate was more than 8 percent. Patients offered drug therapy alone were almost twice as likely to ... Read more

Related support groups: Anxiety, Depression, Generalized Anxiety Disorder, Panic Disorder, Bipolar Disorder, Anxiety and Stress, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Major Depressive Disorder, Seroquel, Celexa, Paxil, Citalopram, Post Traumatic Stress Disorder, Sertraline, Abilify, Amitriptyline

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