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FDA Approves Varubi (rolapitant) for Chemotherapy-Induced Nausea and Vomiting

Posted 2 Sep 2015 by Drugs.com

September 2, 2015 – The U.S. Food and Drug Administration approved Varubi (rolapitant) to prevent delayed phase chemotherapy-induced nausea and vomiting (emesis). Varubi is approved in adults in combination with other drugs (antiemetic agents) that prevent nausea and vomiting associated with initial and repeat courses of vomit-inducing (emetogenic and highly emetogenic) cancer chemotherapy. Nausea and vomiting are common side effects experienced by cancer patients undergoing chemotherapy. Symptoms can persist for days after the chemotherapy drugs are administered. Nausea and vomiting that occurs from 24 hours to up to 120 hours after the start of chemotherapy is referred to as delayed phase nausea and vomiting, and it can result in serious health complications. Prolonged nausea and vomiting can lead to weight loss, dehydration and malnutrition in cancer patients leading to ... Read more

Related support groups: Nausea/Vomiting - Chemotherapy Induced, Varubi, Rolapitant

Anti-Nausea Drug Varubi Approved

Posted 2 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 2, 2015 – Varubi (rolapitant) has been approved by the U.S. Food and Drug Administration to treat nausea and vomiting among adults undergoing cancer chemotherapy. Nausea and vomiting are common side effects of chemotherapy that can persist for days after the drugs are given. Prolonged bouts of these reactions can lead to weight loss, dehydration and malnutrition, the agency said Wednesday in a news release. Varubi was evaluated by some 2,800 participants in three clinical trials, administered in combination with other anti-nausea drugs. The most common side effects included low white blood cell count, hiccups, loss of appetite and dizziness. The FDA said Varubi should not be taken by people who are taking the drug thioridazine, which is commonly prescribed to treat schizophrenia. Varubi is marketed by Tesaro Inc., based in Waltham, Mass. More information The FDA has ... Read more

Related support groups: Nausea/Vomiting - Chemotherapy Induced, Varubi, Rolapitant

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