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Renal Osteodystrophy News

Cutting Salt a Health Boost for Kidney Patients

Posted 7 days ago by Drugs.com

THURSDAY, Feb. 16, 2017 – Encouraging people with kidney disease to reduce their salt intake may help improve blood pressure and cut excess fluid retention, at least for a while, a new study suggests. Study participants lowered their systolic blood pressure (the top number) by almost 11 points, on average, on a salt-restricted diet versus their usual diet. They also flushed out a liter of water (about one-quart) from their bodies, on average, by slashing salt in their diets, researchers said. Having high blood pressure and retaining excess salt and water in the body stresses the heart and blood vessels, explained lead author Dr. Rajiv Saran of the University of Michigan. For kidney disease patients, high blood pressure (or "hypertension") and excess fluid in the body can be a toxic combination. "They die predominantly of cardiovascular disease," said Saran, a professor of internal ... Read more

Related support groups: High Blood Pressure, Hypertension, Renal Failure, Chronic Kidney Disease, Sodium Chloride, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, HalfLytely and Bisacodyl, Renal Osteodystrophy, Hyper-Sal, Rhinaris, Thermotabs, Potassium Chloride/Sodium Chloride, Ayr Saline Nasal, ENTsol, Dextrose/Sodium Chloride, Hypertensive Heart Disease, Saline Nasal Mist

Native Americans Make Progress Against Diabetes Complication

Posted 10 Jan 2017 by Drugs.com

TUESDAY, Jan. 10, 2017 – Diabetes-related kidney failure among Native American adults fell by more than half over almost 20 years, a U.S. Centers for Disease Control and Prevention report shows. The change is due to improvements in diabetes and kidney care, according to the report. The new research also found that among these patients, blood sugar control improved 10 percent between 1996 and 2014, and the use of medicine to protect kidneys rose from 42 percent to 74 percent over 5 years. Average blood pressure in Native Americans with diabetes and high blood pressure was well controlled (133/76 in 2015), the findings showed. In addition, more than 60 percent of Native Americans aged 65 and older with diabetes had a urine test for kidney damage in 2015, compared with 40 percent of Medicare patients with diabetes in 2013, the researchers said. "The Indian Health Service (IHS) has made ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Renal Failure, Glucophage, Novolog, Glipizide, Humalog, Insulin Resistance, Janumet, Glyburide, Levemir, Lantus Solostar, Glimepiride, Pre-Diabetes, Chronic Kidney Disease, Novolin R, Amaryl, Novolin N

Healthy Diet May Mean Longer Life for Kidney Patients

Posted 9 Dec 2016 by Drugs.com

THURSDAY, Dec. 8, 2016 – A healthy diet may help people with kidney disease live longer, researchers report. They analyzed seven studies that included more than 15,000 people with chronic kidney disease, to assess the effects of a diet high in fruits, vegetables, fish, legumes, cereals, whole grains and fiber. In six of the studies, a healthy diet was consistently associated with a 20 percent to 30 percent lower rate of early death, and with 46 fewer deaths per 1,000 people over five years. But the study did not directly prove that a healthy diet would lengthen life. The international team of researchers found no significant association between a healthy diet and risk of kidney failure. The findings were published Dec. 8 in the Clinical Journal of the American Society of Nephrology. "Chronic kidney disease now affects about 10 percent to 13 percent of the adult population and ... Read more

Related support groups: Dietary Supplementation, Renal Failure, Vitamin/Mineral Supplementation and Deficiency, Chronic Kidney Disease, Peritoneal dialysis, Dietary Fiber Supplementation, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Kidney Cancer Drug Shows Promise in Early Trial

Posted 30 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 30, 2016 – An experimental drug may show promise in treating kidney cancer, researchers say. The drug CB-839 is the first to target an enzyme that cancer cells require to stay alive, researchers said. This stage 1 clinical trial found that the drug was effective in most patients with advanced kidney cancer when used in combination with another cancer drug called everolimus (Afinitor, Zortress). In the 15 patients in the study, the dual treatment controlled tumors in 93 percent of the patients, who had either clear cell or papillary renal cell cancer. Tumors shrank by more than 30 percent in one patient, were stable in 13 patients, and grew by more than 20 percent in one patient. Clear cell is the most common form of kidney cancer, accounting for 75 percent of cases, the researchers said. All 12 patients with this type of kidney cancer had their disease controlled. ... Read more

Related support groups: Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Afinitor, Peritoneal dialysis, Everolimus, Renal Osteodystrophy, Wilms' Tumor, Zortress, Hyperphosphatemia of Renal Failure, Afinitor Disperz

Kidney Stone? Try a Roller Coaster Ride

Posted 27 Sep 2016 by Drugs.com

TUESDAY, Sept. 27, 2016 – Anyone who's suffered a kidney stone just wants the urinary obstruction gone. Now, preliminary research suggests relief might even be fun: a roller coaster ride. There's been anecdotal evidence from patients that these amusement park rides can help pass a small stone, explained Dr. David Wartinger, a professor of urology at the Michigan State University College of Osteopathic Medicine, in East Lansing. His team's new research – conducted on the Big Thunder Mountain Railroad and Space Mountain roller coasters at Orlando's Walt Disney World – seems to support that view. In the study, Wartinger's group used 3D printing to create a clear silicone model of a kidney that contained urine, plus three different-sized kidney stones. They placed the kidney model in a backpack and took it on 60 roller coaster rides. "A ride on a moderate-intensity roller coaster could ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Renal Osteodystrophy, Calcium Oxalate Calculi with Hyperuricosuria, Hypercalciuria

Coming Soon: A Wearable Artificial Kidney?

Posted 7 Jun 2016 by Drugs.com

TUESDAY, June 7, 2016 - Someday, dialysis patients might free themselves of clunky machines, moving about with a "wearable artificial kidney" instead. That's the promise of a new clinical trial that suggests this type of technology is finally within reach. "This would be a game changer," said one kidney specialist, Dr. Maria DeVita. "The fact that clinical trials are beginning gives us all hope that we will have a significant improvement in the care of those patients requiring ongoing hemodialysis." DeVita is associate director of nephrology at Lenox Hill Hospital in New York City. People with advanced kidney disease must often resort to spending hours a day at dialysis centers, with special machines cleansing their blood as their kidneys once did. The dream has long been a small portable device that could perform dialysis as patients went about their usual day. That dream may be ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Diabetic Kidney Disease, Nephrotic Syndrome, Hemodialysis, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, Polycystic Kidney Disease, Diagnosis and Investigation, Renal Osteodystrophy, Alport Syndrome, Hyperphosphatemia of Renal Failure, Anuria, Hypertensive Renal Disease, Hemodialysis Anticoagulation, Renal and Genitourinary Disorders

Study Links Climate Change to Kidney Disease

Posted 5 May 2016 by Drugs.com

THURSDAY, May 5, 2016 – Climate change may boost rates of chronic kidney disease worldwide as rising temperatures and heat stress harm kidneys, researchers report. They analyzed global data and found that heat stress-related chronic kidney disease appears to be on the rise in rural communities in hot regions. The risk of heat stress-related chronic kidney disease has increased due to global warming and an increase in extreme heat waves, and is highest for certain groups of people, such as agricultural workers, according to the study authors. The authors also noted that decreasing amounts of rain contribute to the growing epidemic of heat stress nephropathy – or chronic kidney disease consistent with heat stress – by reducing water supplies and quality as temperatures rise. The study findings will be published in an upcoming issue of the Clinical Journal of the American Society of ... Read more

Related support groups: Renal Failure, Kidney Infections, Chronic Kidney Disease, Peritoneal dialysis, Pyelonephritis, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Medicare Spends Billions on Chronic Kidney Disease, Study Finds

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – Chronic kidney disease affects nearly 14 percent of Americans and costs Medicare billions of dollars a year, a new study reveals. In 2013, Medicare spent $50 billion on chronic kidney disease among people 65 and older, and $31 billion on those with kidney failure, the researchers found. "This report is a one-stop shop to try to understand the prevalence of kidney disease, how it's being treated and how the burden affects various populations," researcher Rajesh Balkrishnan, a professor of public health sciences at the University of Virginia School of Medicine, said in a university news release. "If we can identify which treatment modalities are working and how they're used and link these treatments to outcomes, we can inform the government of the most cost-effective ways to manage and treat the growing burden of kidney disease in the U.S.," he added. The study ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, Renal Osteodystrophy, Renovascular Hypertension, Anuria, Hyperphosphatemia of Renal Failure, Hypertensive Heart (w/ CHF) and Renal Disease, Renal Artery Atherosclerosis, Renal and Genitourinary Disorders, Hypertensive Renal Disease

Paying for Kidneys Might Boost Donor Rate, Study Says

Posted 23 Mar 2016 by Drugs.com

WEDNESDAY, March 23, 2016 – If offered $50,000, nearly three out of five Americans would part with a kidney, a new study finds. "It appears that American society is ready to accept the concept of paying kidney donors," said lead researcher Dr. Thomas Peters, an emeritus professor of surgery at the University of Florida College of Medicine, in Jacksonville. However, Peters isn't suggesting that a paid market for kidneys start anytime soon, only that the idea be studied to see if it might increase the supply of kidneys. Paying for organs is illegal under the U.S. National Organ Transplant Act. When the law was enacted, "the feeling was that altruism should prevail," Peters said. "Organs should not become a commodity, and the giving was as important as receiving. "Laws should be amended or changed, so at least pilot studies regarding this question could be carried out to see if kidney ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Poor Leg Circulation Hits Women With Kidney Disease Earlier Than Men

Posted 23 Feb 2016 by Drugs.com

TUESDAY, Feb. 23, 2016 – Compared to men, women under the age of 70 who have kidney disease are at higher odds for peripheral arterial disease (PAD), an often disabling impairment of blood flow in the legs. That's the finding from a new study of almost 3,200 people with chronic kidney disease. Researchers led by Dr. Grace Wang, of the Hospital of the University of Pennsylvania in Philadelphia, found that women under 70 with kidney disease had a 53 percent higher risk of PAD compared to their male peers. However, after age 70 the difference between the sexes evened out, the researchers noted. Why would PAD affect women earlier? According to the study authors, "females are known to have smaller diameter vessels compared to men." That could mean that, given similar amounts of plaque buildup in vessels, women's might close off earlier than men's. The findings show that women with kidney ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Raynaud's Syndrome, Peripheral Arterial Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Intermittent Claudication, Renal Osteodystrophy, Renal and Genitourinary Disorders, Arterial Thrombosis

Severe Gum Disease May Boost Death Rate of Kidney Disease Patients

Posted 18 Feb 2016 by Drugs.com

THURSDAY, Feb. 18, 2016 – Severe gum disease increases the risk of death in chronic kidney disease patients, a new study suggests. The findings add to growing evidence that poor oral health is associated with other chronic diseases, according to the researchers at the University of Birmingham in England. They analyzed data from more than 13,700 Americans who took part in a federal government health survey. They found the 10-year death rate among chronic kidney disease patients was 41 percent for those with severe gum disease, compared with 32 percent for those without severe gum disease. The study was published Feb. 18 in the Journal of Clinical Periodontology. Severe gum disease affects more than 11 percent of people worldwide, the researchers said. "It's important to note that oral health isn't just about teeth. The mouth is the doorway to the body, rather than a separate organ, and ... Read more

Related support groups: Oral and Dental Conditions, Xerostomia, Toothache, Renal Failure, Gingivitis, Chronic Kidney Disease, Peritoneal dialysis, Periodontitis, Prevention of Dental Caries, Renal Osteodystrophy

Anemia Drugs May Not Boost Kidney Patients' Well-Being: Study

Posted 16 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – The pricey anemia drugs often given to people with chronic kidney disease may make no difference in how they feel day to day, a new research review confirms. Researchers said the study results back up current guidelines on how to use the drugs, called erythropoietin-stimulating agents (ESAs). These include the injection drugs marketed under the names Procrit, Epogen and Aranesp. Patients may still benefit from the medications because they reduce the need for blood transfusions to treat severe anemia, said Dr. Navdeep Tangri, senior researcher on the study. "But this should close the book on the idea that these drugs help with exhaustion and improve patients' quality of life," said Tangri, an attending doctor at Seven Oaks General Hospital Renal Program in Manitoba, Canada. However, one expert argued that while on average, that is true, some patients do feel ... Read more

Related support groups: Anemia, Renal Failure, Chronic Kidney Disease, Peritoneal dialysis, Aranesp, Procrit, Epogen, Renal Osteodystrophy, Mircera, Darbepoetin Alfa, Anemia Associated with Chronic Disease, Epoetin Beta-Methoxy Polyethylene Glycol, Peginesatide, Hyperphosphatemia of Renal Failure, Epoetin Alfa, Omontys

Racial Disparity in Kidney Transplant Outcomes Narrows: Study

Posted 5 Feb 2016 by Drugs.com

THURSDAY, Feb. 4, 2016 – Racial disparities in kidney transplant outcomes are shrinking, new research indicates. Previous studies had shown that black patients who received kidney transplants had worse outcomes compared with white patients. But a new analysis of roughly 200,000 kidney transplants revealed that the success of surgeries involving black people improved between 1990 and 2012, with fewer organ rejections and deaths among these patients. The study authors compared information on almost 64,000 black and more than 145,400 white adults who received a kidney from a living or deceased donor. The findings were published online Feb. 4 in the Journal of the American Society of Nephrology. "We hypothesized that advances in immunosuppression and post-transplant management might differentially benefit black kidney transplant recipients, who were disproportionately burdened by ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Graft-versus-host disease, Rejection Prophylaxis, Hyperphosphatemia of Renal Failure

New Kidney Transplant Drug Cuts Risk of Earlier Death: Study

Posted 28 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – A newer drug used for preventing organ rejection might improve the long-term outlook for kidney transplant recipients, a new study finds. Over seven years, patients given the drug belatacept (brand name: Nulojix) were 43 percent less likely to die or see their donor kidney fail compared to patients given an older drug called cyclosporine. Experts said the findings should encourage more doctors and patients to choose belatacept over standard anti-rejection medications. "This is a potentially transformational drug," said study lead researcher Dr. Flavio Vincenti, a transplant specialist at the University of California, San Francisco. The study – funded by the drug's maker, Bristol-Myers Squibb – was published in the Jan. 28 issue of the New England Journal of Medicine. Belatacept was first approved by the U.S. Food and Drug Administration in 2011 for ... Read more

Related support groups: Renal Failure, Kidney Infections, Restasis, Chronic Kidney Disease, Cyclosporine, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Neoral, Organ Transplant - Rejection Reversal, Pyelonephritis, Renal Osteodystrophy, Graft-versus-host disease, Gengraf, Rejection Prophylaxis, Sandimmune, Nulojix, Hyperphosphatemia of Renal Failure, Belatacept

Kidney Woes Tied to Raised Cancer Risk, Study Finds

Posted 12 Nov 2015 by Drugs.com

THURSDAY, Nov. 12, 2015 – Kidney failure and having a kidney transplant may increase the risk for certain types of cancer, a new study suggests. Poor kidney function and immune system-suppressing drugs may be behind this increased risk, according to Elizabeth Yanik, of the U.S. National Cancer Institute, and colleagues. For the study, published in the Nov. 12 online edition of the Journal of the American Society of Nephrology, the researchers looked at data from more than 200,000 U.S. kidney transplant candidates and recipients. Along with finding that these patients are at increased risk for certain types of cancer, the investigators also identified clear patterns of risk associated with different types of treatment. However, the associations seen in the study do not prove cause-and-effect. The risk of kidney and thyroid cancers was especially high when kidney failure patients were on ... Read more

Related support groups: Cancer, Methotrexate, Renal Failure, CellCept, Gilenya, Tysabri, Imuran, Chronic Kidney Disease, Xolair, Orencia, Revlimid, Leflunomide, Azathioprine, Arava, Afinitor, Tecfidera, Mycophenolate Mofetil, Peritoneal dialysis, Aubagio, Benlysta

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