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Related terms: Acute Kidney Failure, Acute Renal Failure, Chronic Renal Failure, Kidney Failure, CRF

Limiting 'Cold Time' Could Make More Organs Available for Transplant

Posted 14 days ago by Drugs.com

THURSDAY, Oct. 5, 2017 – By improving the way certain donated organs are handled before a transplant, more organs could end up being used, new research suggests. The concern centers on organs donated following "circulatory death" (DCD). That means a patient's heart, breathing and circulation stop functioning. Most donated organs come from people who are brain dead, but their circulation is continued with machines. Organs donated by DCD must undergo a controlled cooling process (called "cold ischemia") after the organ loses its original blood supply. The organ is then re-warmed when blood supply is renewed at the time of transplant. This process leads to a heightened risk for tissue damage. But a team led by Dr. John Gill of the University of British Columbia and Vancouver's Providence Health Care found that by limiting the cooling process to a period of no more than 12 hours, DCD ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Kidney Transplant, Organ Transplant - Rejection Reversal, Rejection Prophylaxis, Hyperphosphatemia of Renal Failure, Rejection Reversal

Dialysis Patients Often End Up Back in the Hospital

Posted 29 Sep 2017 by Drugs.com

FRIDAY, Sept. 29, 2017 – Nearly one-quarter of kidney dialysis patients admitted to the hospital are readmitted within 30 days after discharge, a new study finds. In many cases, the readmissions are for a different problem than the one that led to the first hospitalization, according to the report. For the study, researchers reviewed data from nearly 391,000 initial hospitalizations of dialysis patients in the United States in 2013. Within 30 days after leaving the hospital, 22 percent of the patients had unplanned readmissions. Only 20 percent of those readmissions were for the same diagnosis as the first admission, the findings showed. Just 2 percent of all patients accounted for 20 percent of all readmissions. Women and younger people were more likely to be readmitted, the researchers found. In addition, people who were depressed, had liver disease, heart failure or who abused drugs ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Hemodialysis, Peritoneal dialysis, Renal and Genitourinary Disorders

Addictive Opioids Common for People on Dialysis

Posted 21 Sep 2017 by Drugs.com

THURSDAY, Sept. 21, 2017 – Kidney dialysis patients in the United States have high rates of prescriptions for opioid painkillers and many also receive high doses of the potentially addictive drugs, a new study finds. Pain is common in dialysis patients, the study authors explained in a news release from the American Society of Nephrology. But these patients can't take certain drugs because their failing kidneys can't process them. This makes pain control difficult. For the new study, researchers reviewed Medicare data from 2006 through 2010. The investigators found that nearly two-thirds of dialysis patients received at least one opioid prescription every year. More than 20 percent received repeated prescriptions. In addition, more than 25 percent of patients given opioid prescriptions received higher-than-recommended doses. The use of opioids was associated with increased risks of ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Hydrocodone, Tramadol, Percocet, Methadone, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Chronic Pain, Opana, Subutex, Dilaudid, Opana ER, Roxicodone

Exercise May Stem Kidney Damage in Lupus Patients

Posted 19 Sep 2017 by Drugs.com

TUESDAY, Sept. 19, 2017 – Regular exercise may slow kidney damage in people with lupus while stress may prompt the opposite effect, new research suggests. The autoimmune disease causes the body to attack and damage vital organs such as the kidneys. Singer Selena Gomez put lupus in the spotlight last week when she received a kidney transplant because the disease had ravaged her own kidneys. But the new research, which included two mice trials and a slightly different human trial, offers new strategies that might help other lupus patients avoid the same fate. In the first trial, only 45 percent of mice with the disease that did moderate exercise (45 minutes of treadmill walking a day) had severe inflammatory damage to the kidneys, compared with 88 percent of those that did not exercise. In another experiment, mice with lupus that were subjected to daily stress had significant increases ... Read more

Related support groups: Anxiety and Stress, Systemic Lupus Erythematosus, Renal Failure, Chronic Kidney Disease, Lupus Erythematosus, Renal and Genitourinary Disorders

Selena Gomez's Kidney Transplant Puts Lupus Center Stage

Posted 15 Sep 2017 by Drugs.com

FRIDAY, Sept. 15, 2017 – When pop star Selena Gomez revealed Thursday that she had a kidney transplant, she put the autoimmune disease lupus in the spotlight. Lupus turns the body's immune system against itself and attacks vital organs, including the kidneys, which is why it's so devastating. But little is known about what causes the disease, and no real cure exists. Treatments can only keep it at bay. "Selena has a lot of courage to speak out about her condition and call attention to lupus," said Dr. Anca Askanase. She is clinical director of the Lupus Center at Columbia University Medical Center in New York City. Because Gomez needed a transplant at age 25, she probably developed lupus at an early age, added Askanase, who is also a spokeswoman for the Lupus Research Alliance. The superstar singer first told Billboard in 2015 that she had been diagnosed with lupus and was undergoing ... Read more

Related support groups: Smoking, Systemic Lupus Erythematosus, Renal Failure, Chronic Kidney Disease, Lupus Erythematosus, Kidney Transplant

Diabetes Threatens Kidneys, Vision of Millions of Americans

Posted 13 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 13, 2017 – Millions of Americans with type 2 diabetes and pre-diabetes are at risk for chronic kidney disease, and another 59,000 Americans, 40 and older, are at risk for diabetes-related blindness. That's the sobering conclusion of new research by investigators at the U.S. Centers for Disease Control and Prevention. The good news is that, in many cases, these complications can be reversed or their progression slowed, said Dr. Joel Zonszein. He's director of the Clinical Diabetes Center at Montefiore Medical Center in New York City. He wasn't involved with the new study. "When we talk about prevention, we are really talking not about disease prevention, but rather about sustaining good quality of life by delaying more complications," he said. "We can prevent complications by changes in lifestyle and the correct medications," Zonszein added. In fact, many patients with ... Read more

Related support groups: Diabetes, Type 2, Renal Failure, Insulin Resistance, Pre-Diabetes, Chronic Kidney Disease, Diabetes Mellitus, Abnormal Glucose Tolerance, Visual Defect/Disturbance, Hyperphosphatemia of Renal Failure

Pot Won't Harm Healthy Young People's Kidneys, Study Suggests

Posted 25 Aug 2017 by Drugs.com

THURSDAY, Aug. 24, 2017 – There's still a lot that scientists don't know about how marijuana affects people's health, but new research suggests that smoking pot doesn't seem to take a toll on healthy young kidneys. Studies with animals had suggested regular pot use could alter kidney function. But the authors of the new study found no evidence to support that claim, at least among healthy young adults who were followed for up to 15 years. "Results from our observational study in young adults with normal kidney function may not translate into a clinically meaningful difference and may be insufficient to inform decision-making concerning marijuana use," said Dr. Julie Ishida, who worked on the study. She's with the University of California, San Francisco, and San Francisco VA Medical Center. The researchers used data from the Coronary Artery Risk Development in Young Adults (CARDIA) ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Cannabis, Peritoneal dialysis

Kidney Disease May Boost Odds of Infection

Posted 18 Aug 2017 by Drugs.com

FRIDAY, Aug. 18, 2017 – As kidney function declines, infection risk rises, a new study shows. Infections facing people with advanced kidney disease include lower respiratory tract disease, urinary tract infections and blood poisoning, researchers said. The findings were published Aug. 17 in the Clinical Journal of the American Society of Nephrology. "Given the fact that chronic kidney disease remains underdiagnosed and unrecognized in most societies, our findings may help patients and clinicians become more aware of chronic kidney disease and its complications," said co-lead author Juan Jesus Carrero, of the Karolinska Institute in Sweden. "This in turn may be useful to identify patients at increased risk of infection and inform discussions about prevention strategies, such as vaccination and health service planning," Carrero said in a journal news release. The researchers tracked 12 ... Read more

Related support groups: Infections, Urinary Tract Infection, Renal Failure, Chronic Kidney Disease, Renal and Genitourinary Disorders

Kidney Disease May Boost Risk of Abnormal Heartbeat

Posted 10 Aug 2017 by Drugs.com

THURSDAY, Aug. 10, 2017 – People with failing kidneys are at increased risk of developing a life-threatening abnormal heart rhythm, a new report suggests. Chronic kidney disease can as much as double a patient's risk of atrial fibrillation, a quivering or irregular heartbeat that can lead to stroke or heart failure, said lead researcher Dr. Nisha Bansal. She is an associate professor of nephrology at the University of Washington's Kidney Research Institute, in Seattle. The risk of atrial fibrillation increases as kidney function declines, Bansal said. "We saw the worse your kidney function, the greater your risk of developing atrial fibrillation. Even mild changes in kidney function were strongly linked to atrial fibrillation," Bansal noted. The study included data gathered from three separate research projects focused on heart health in the United States. The three projects created a ... Read more

Related support groups: Atrial Fibrillation, Renal Failure, Prevention of Thromboembolism in Atrial Fibrillation, Chronic Kidney Disease, Peritoneal dialysis, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Asthma Drug May Help Kidney Patients Regain Sense of Smell

Posted 3 Aug 2017 by Drugs.com

THURSDAY, Aug. 3, 2017 – A common problem among chronic kidney disease patients is a loss of the sense of smell, which could lead to an inadequate diet, researchers say. In turn, malnutrition in these patients can result in poor quality of life, poor overall health and even early death. But a new study found that using an inhaled asthma drug might improve the sense of smell in kidney failure patients. "Our ultimate goal is to have an intervention that can alleviate smell loss, and thus to improve the kidney patients' nutritional status," study co-leader Dr. Sagar Nigwekar said in a news release from the American Society of Nephrology. The study included 36 patients with chronic kidney disease, 100 with kidney failure and 25 with normal kidney function. Average scores on odor identification tests were about 76 percent among the kidney disease patients, 67 percent for those with kidney ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Hyperphosphatemia of Renal Failure, Theolair

Novel Procedure Improves Kidney Transplant Success

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – A new treatment might open the door for more patients with advanced kidney disease to get a transplant, a preliminary study suggests. Of the 100,000-plus Americans waiting for a donor kidney, about one-third are "sensitized," said Dr. Robert Montgomery, director of the Transplant Institute at NYU Langone in New York City. Those patients face a tough situation: They harbor immune system antibodies that are primed to attack a donor organ. The antibodies can form when a person is exposed to foreign tissue, Montgomery explained. So a patient who's had a prior kidney transplant may be highly sensitized – meaning they have a large number of the offending antibodies. It can also happen to patients who've had blood transfusion or ever been pregnant, Montgomery said. It's almost impossible to find a compatible donor for those patients. But they might be able to ... Read more

Related support groups: Anxiety, Generalized Anxiety Disorder, Anxiety and Stress, Social Anxiety Disorder, Renal Failure, Rituxan, Rituximab, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Hyqvia, Rejection Prophylaxis, Rituxan Hycela, Hyaluronidase/immune Globulin, Hyaluronidase/rituximab

Drug for Kidney Disease Tied to Infection Risk

Posted 1 Aug 2017 by Drugs.com

TUESDAY, Aug. 1, 2017 – A drug used for some cases of kidney disease can raise the risk of serious infections, researchers say. A clinical trial was stopped early when researchers discovered that patients on the drug – a corticosteroid called methylprednisolone – suffered a concerning number of serious side effects. Most often, that meant severe infections, including pneumonia and meningitis. Overall, nearly 15 percent of patients on the drug had a serious "adverse event" over two years, the investigators found. That compared with 3 percent of patients given placebo pills, the researchers reported. The study focused on patients with a form of kidney disease called immunoglobulin A (IgA) nephropathy. It arises when IgA – an immune system protein – builds up in the kidneys, leading to inflammation. Methylprednisolone and other corticosteroids suppress the immune system and quell ... Read more

Related support groups: Methylprednisolone, Pneumonia, Renal Failure, Medrol, Chronic Kidney Disease, Meningitis, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Diagnosis and Investigation, IgA Nephropathy, Methylprednisolone Topical, A-methapred, Adlone-40, Methacort 40, Med-Jec-40, Dep Medalone 80, Methylcotol, Medralone

Researchers Grow Functioning Liver Tissue in Mice

Posted 19 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – Researchers say they were able to coax tiny "seeds" of liver tissue into fully functioning livers in mice. If this approach works in people, it could help reduce long wait lists for liver transplants. It might also benefit people with failing livers who don't quality for liver transplants, according to the researchers. The scientists placed three types of liver cells – the seeds – into biodegradable tissue scaffolds. They then implanted those scaffolds in mice with damaged livers. Once inside the mice, the tiny structures grew 50-fold and were able to perform normal liver tissue functions. "There are just not enough organs to go around. Our goal is that one day we could use this technology to increase the number of transplants that are done for patients, which right now is very limited," said senior author Dr. Sangeeta Bhatia. She's a professor of health ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Kidney Transplant, Liver and Pancreatic Disease

Thyroid Problems May Make Things Worse for Dialysis Patients

Posted 14 Jul 2017 by Drugs.com

THURSDAY, July 13, 2017 – Poor thyroid function may diminish kidney dialysis patients' health and quality of life, a new study suggests. Hypothyroidism – a condition in which the thyroid gland does not produce enough thyroid hormone – is common in dialysis patients, but how it affects them has been unclear. Dialysis is treatment for kidney failure, where patients need a machine to filter their blood of wastes, salts and extra fluids. This study included 450 dialysis patients who completed questionnaires every six months and had their thyroid function assessed. Poor thyroid function was associated with poorer health-related quality of life, including low energy, increased fatigue, reduced physical function and greater pain. "Given the high prevalence of thyroid dysfunction and low levels of quality of life in dialysis patients, future research is needed to determine the underlying ... Read more

Related support groups: Thyroid Disease, Hypothyroidism, Underactive Thyroid, Renal Failure, Hyperthyroidism, Chronic Kidney Disease, Goiter, Hemodialysis, Peritoneal dialysis, Renal and Genitourinary Disorders, Hemodialysis Anticoagulation

Are Doctors Discarding Donor Kidneys That Could Save Lives?

Posted 7 Jul 2017 by Drugs.com

THURSDAY, July 6, 2017 – U.S. doctors are discarding donated kidneys that could keep people alive for years, simply because the organs are not top-quality, a new study claims. "Suboptimal" kidneys from older donors with health problems perform much better than expected, and would preserve a patient's life much longer than dialysis, said lead researcher Dr. Sumit Mohan, an assistant professor at Columbia University's Mailman School of Public Health. About 73 percent of lower-quality kidneys received by Columbia patients were still functioning five years after transplant, Mohan and his colleagues found. "To our surprise, yes, they did worse than the best-quality kidneys, but they didn't do that poorly," Mohan said. By comparison, the five-year survival rate for kidney patients on dialysis is about 35 percent, Mohan said. "If I don't get a kidney, my alternative is to stay on dialysis," ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Peritoneal dialysis, Organ Transplant, Kidney Transplant, Organ Transplant - Rejection Reversal, Nephropathy, Rejection Prophylaxis, Renal and Genitourinary Disorders, Hyperphosphatemia of Renal Failure, Rejection Reversal

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