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Renal Cell Carcinoma News

Related terms: Adenocarcinoma of renal cells, Cancer, Hypernephroma, Cancer, Kidney, Cancer, Renal, Cancer, Renal Cell Carcinoma, Hypernephroma, Kidney Cancer, Renal Cancer

FDA Approves Sutent (sunitinib malate) for Adjuvant Treatment of Adult Patients at High Risk of Recurrent Renal Cell Carcinoma

Posted 20 Nov 2017 by Drugs.com

November 16, 2017 – The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy). Adjuvant treatment is a form of therapy that is taken after an initial surgical removal to lower the risk of the cancer coming back. “This is the first adjuvant treatment approved for patients with renal cell carcinoma, which is significant because patients with this disease who have a nephrectomy are often at high risk of the cancer returning,” said Richard Pazdur, M.D., director of the FDA’s Oncology Center of Excellence and acting director of the Office of Hematology and Oncology Products in the FDA’s Center for Drug Evaluation and Research. “There is now an approved therapy for patients who previously did not have options t ... Read more

Related support groups: Renal Cell Carcinoma, Sutent, Sunitinib

FDA Approves Mvasi (bevacizumab-awwb), a Biosimilar to Avastin

Posted 17 Sep 2017 by Drugs.com

September 14, 2017 – The U.S. Food and Drug Administration today approved Mvasi (bevacizumab-awwb) as a biosimilar to Avastin (bevacizumab) for the treatment of multiple types of cancer. Mvasi is the first biosimilar approved in the U.S. for the treatment of cancer. “Bringing new biosimilars to patients, especially for diseases where the cost of existing treatments can be high, is an important way to help spur competition that can lower healthcare costs and increase access to important therapies,” said FDA Commissioner Scott Gottlieb, M.D. “We’ll continue to work hard to ensure that biosimilar medications are brought to the market quickly, through a process that makes certain that these new medicines meet the FDA’s rigorous gold standard for safety and effectiveness.” Mvasi is approved for the treatment of adult patients with certain colorectal, lung, brain, kidney and cervical cancers ... Read more

Related support groups: Cancer, Renal Cell Carcinoma, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Avastin, Cervical Cancer, Glioblastoma Multiforme, Bevacizumab, Mvasi

FDA OKs First 'Biosimilar' Drug to Fight Cancer, Mvasi

Posted 14 Sep 2017 by Drugs.com

THURSDAY, Sept. 14, 2017 – The first approval of a biosimilar drug to treat cancer was announced Thursday by the U.S. Food and Drug Administration. Mvasi (bevacizumab-awwb) was approved as a biosimilar to Avastin (bevacizumab) for the treatment of adults with certain colon, lung, brain, kidney and cervical cancers. A biosimilar is a biological product that is approved because it is highly similar to an already-approved biologic drug and has no significant differences in safety and effectiveness from the first product, the FDA explained. "Bringing new biosimilars to patients, especially for diseases where the cost of existing treatments can be high, is an important way to help spur competition that can lower health care costs and increase access to important therapies," FDA Commissioner Dr. Scott Gottlieb said in an agency news release. Mvasi is marketed by Amgen, Inc., headquartered in ... Read more

Related support groups: Cancer, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Brain Tumor, Avastin, Cervical Cancer, Bevacizumab, Mvasi

Many Terminal Cancer Patients Remain in Denial

Posted 20 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – Nearly 10 percent of patients with terminal cancer don't want to know they're dying, which can make their final days more difficult, a new study finds. Unwillingness to face poor prospects can lead to unnecessary treatments and keep patients from making end-of-life plans, the researchers reported recently in The Oncologist. "Health care professionals should appropriately assess patients' readiness for prognostic information," said study leader Siew-Tzuh Tang, a professor at Chang Gung University School of Nursing in Taiwan. Doctors should respect patients' reluctance to confront their poor prognosis if they are not ready to know, "but sensitively coach them to cultivate their accurate prognostic awareness," Tang said in a journal news release. The study involved nearly 250 terminal cancer patients in Taiwan. They were questioned several times over their last ... Read more

Related support groups: Anxiety, Generalized Anxiety Disorder, Anxiety and Stress, Cancer, Post Traumatic Stress Disorder, Social Anxiety Disorder, Breast Cancer, Prostate Cancer, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Skin Cancer, Ovarian Cancer, Pancreatic Cancer, Cervical Cancer, Breast Cancer, Prevention, Head and Neck Cancer

'Couch Potatoes' May Face Higher Risk of Kidney, Bladder Cancers

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – Add greater risk of kidney and bladder cancer to the long list of why a lifetime of sitting on the sofa isn't good for your health, a new study suggests. Specifically, lifetime recreational inactivity was associated with a 73 percent increased risk of bladder cancer and a 77 percent increased risk of kidney cancer. The findings add to growing evidence that inactivity may be a significant risk factor for cancer, the researchers said. "We hope that findings like ours will motivate inactive people to engage in some form of physical activity," said study senior author Kirsten Moysich. She is a professor of oncology at Roswell Park Cancer Institute in Buffalo, N.Y. "You don't have to run marathons to reduce your cancer risk, but you have to do something – even small adjustments like taking the stairs instead of the elevator, walking around the block a couple of ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Bladder Cancer, Solid Tumors, Urothelial Carcinoma

Survival Continues to Improve for Most Cancers

Posted 31 Mar 2017 by Drugs.com

FRIDAY, March 31, 2017 – Overall cancer death rates in the United States continue to fall, but racial gaps persist, a new report says. Death rates fell between 2010 and 2014 for 11 of the 16 most common cancers in men and for 13 of the most common types in women, including lung, colon, prostate and breast cancers. However, death rates rose for cancers of the liver, pancreas and brain in men and for the liver and uterus in women. And improvements in cancer survival weren't equal for all Americans. "While this report found that five-year survival for most types of cancer improved among both blacks and whites over the past several decades, racial disparities for many common cancers have persisted, and they may have increased for prostate cancer and female breast cancer," said Dr. Lynne Penberthy. She's associate director of the U.S. National Cancer Institute's Surveillance Research ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Skin Cancer, Melanoma, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Pancreatic Cancer, Small Cell Lung Cancer, Breast Cancer - Adjuvant, Bladder Cancer, Cervical Cancer, Breast Cancer, Prevention

Another Study Ties Obesity to Certain Cancers

Posted 1 Mar 2017 by Drugs.com

WEDNESDAY, March 1, 2017 – Carrying extra weight increases the risk of a number of cancers, a new review reports. Additional pounds appear to particularly influence the risk of cancers related to the digestive organs or those driven by hormonal abnormalities, according to the review's European authors. The evidence is so strong at this point that important organizations such as the International Agency for Research on Cancer describe "excess body weight as an important cause of cancers," said Susan Gapstur. She's vice president of epidemiology at the American Cancer Society. The new evidence review was led by Maria Kyrgiou, of Imperial College London's Department of Surgery and Cancer. The review found that a jump in a person's body mass index (BMI) of 5 was associated with a higher cancer risk in the esophagus, bone marrow, biliary tract system, pancreas and kidneys. BMI is a rough ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, Colorectal Cancer, Ovarian Cancer, Endometrial Cancer, Pancreatic Cancer, Stomach Cancer, Gastric Cancer, Wilms' Tumor, Solid Tumors, Neoplasm of Bone, Insulinoma, Peritoneal Cancer, Giant Cell Tumor of Bone

Toxins in Your Fast-Food Packaging?

Posted 1 Feb 2017 by Drugs.com

WEDNESDAY, Feb. 1, 2017 – Many grease-resistant fast-food wrappers and boxes contain potentially harmful chemicals that can leach into food, a new study contends. Testing on more than 400 samples from restaurants nationwide revealed that nearly half of fast-food wrappers and one out of five paperboard food boxes contained detectable levels of fluorine, said lead researcher Laurel Schaider. She's an environmental chemist at the Silent Spring Institute in Newton, Mass. Previous studies have linked some fluorinated chemicals such as perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) to kidney and testicular cancer, low birth weight, thyroid disease, decreased sperm quality, pregnancy-induced high blood pressure, and immune system problems in children, the study authors said in background notes. Major U.S. manufacturers voluntarily phased out PFOA and PFOS for most uses ... Read more

Related support groups: High Blood Pressure, Hypertension, Thyroid Disease, Renal Cell Carcinoma, Immunosuppression, Poisoning, Premature Labor, Testicular Cancer, Toxic Reactions Incl Drug and Substance Abuse, Labor Pain, Hypertensive Heart Disease, Prematurity/Underweight in Infancy

Kidney Cancer Drug Shows Promise in Early Trial

Posted 30 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 30, 2016 – An experimental drug may show promise in treating kidney cancer, researchers say. The drug CB-839 is the first to target an enzyme that cancer cells require to stay alive, researchers said. This stage 1 clinical trial found that the drug was effective in most patients with advanced kidney cancer when used in combination with another cancer drug called everolimus (Afinitor, Zortress). In the 15 patients in the study, the dual treatment controlled tumors in 93 percent of the patients, who had either clear cell or papillary renal cell cancer. Tumors shrank by more than 30 percent in one patient, were stable in 13 patients, and grew by more than 20 percent in one patient. Clear cell is the most common form of kidney cancer, accounting for 75 percent of cases, the researchers said. All 12 patients with this type of kidney cancer had their disease controlled. ... Read more

Related support groups: Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Afinitor, Peritoneal dialysis, Everolimus, Wilms' Tumor, Renal Osteodystrophy, Zortress, Hyperphosphatemia of Renal Failure, Afinitor Disperz

Freeze Therapy: An Alternative to Breast Cancer Surgery?

Posted 12 Oct 2016 by Drugs.com

TUESDAY, Oct. 11, 2016 – A freezing technique known as cryoablation might be a viable alternative to lumpectomy for treating small, early stage breast cancers, researchers report. In the small study of 86 patients, "cryoablation was shown to successfully [treat] the majority of small breast cancers with few side effects or complications," said study co-author Dr. Deanna Attai. She's an assistant clinical professor of surgery at the University of California, Los Angeles David Geffen School of Medicine. Using this minimally invasive approach to destroy cancer cells, there should be little to no change in the appearance of the breast, said Attai, immediate past president of the American Society of Breast Surgeons. The major risk, Attai said, is not killing all the cancerous cells. Another surgeon noted that although further research is still needed, cryoablation appears to be "a potential ... Read more

Related support groups: Cancer, Breast Cancer, Renal Cell Carcinoma, Lung Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention

Do Overweight People Fare Better Than Others With Kidney Cancer?

Posted 7 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Obesity is a risk factor for kidney cancer. Yet, obese people with advanced kidney cancer seem to live longer than normal-weight or underweight patients, a new study finds. In one database of nearly 2,000 patients with advanced kidney cancer, those who were obese or overweight survived nearly 26 months, compared to 17 months for those of normal weight. And, overweight patients were 16 percent less likely to die during the study period, the researchers reported. Similar findings were uncovered using three other databases. The records of more than 7,000 kidney cancer patients were reviewed by the study authors. "Paradoxically, when overweight individuals developed kidney cancer, especially in its advanced, metastatic form, their disease progressed more slowly and they lived longer than their normal-weight counterparts," said lead researcher Dr. Toni Choueiri. ... Read more

Related support groups: Obesity, Cancer, Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Wilms' Tumor, Urinary Tract Tumors, Urinary Tract Cancer

Excess Weight Tied to Higher Risk for Many Cancers, Experts Say

Posted 25 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 23, 2016 – Staying slim throughout your life might lower your risk of developing at least eight types of cancer, an international cancer research group says. Those include cancers of the stomach, liver, gallbladder, pancreas, ovary and thyroid. The list also includes a form of brain cancer known as meningioma, as well as a type of blood cancer called multiple myeloma. What's more, the latest research builds on the findings of an earlier review by the International Agency for Research on Cancer (IARC), which is part of the World Health Organization. That research found that those who avoid gaining weight can curtail their risk for developing five other types of cancer, including cancer of the colon, esophagus, kidney, breast and uterus. "The review certainly concluded crystal clear, as you say, that obesity causes cancer," noted Dr. Graham Colditz, who chaired the IARC ... Read more

Related support groups: Obesity, Cancer, Breast Cancer, Renal Cell Carcinoma, Colorectal Cancer, Head and Neck Cancer, Urinary Tract Cancer

FDA Approves Lenvima (lenvatinib) for the Treatment of Patients with Advanced Renal Cell Carcinoma

Posted 16 May 2016 by Drugs.com

WOODCLIFF LAKE, N.J., May 13, 2016 /PRNewswire/ – Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) approved Lenvima (lenvatinib), the company's multiple receptor tyrosine kinase inhibitor, in combination with everolimus for the treatment of patients with advanced renal cell carcinoma (aRCC) who were previously treated with an anti-angiogenic therapy. This approval was based on the impressive results of the registration study (Study 205), in which the once daily combination of 18 mg Lenvima and 5 mg everolimus demonstrated a substantial improvement in progression-free survival (PFS), powerful objective response rate (ORR) and clinically meaningful overall survival (OS) when compared with everolimus alone, a standard of care for patients with aRCC who have received prior anti-angiogenic therapy. "Lenvatinib plus everolimus is the first and only FDA-approved ... Read more

Related support groups: Renal Cell Carcinoma, Lenvima, Lenvatinib

Could Talk Therapy Ease Chemo-Related Memory Issues?

Posted 2 May 2016 by Drugs.com

MONDAY, May 2, 2016 – A type of psychotherapy might help cancer survivors deal with the long-term thinking problems some experience after chemotherapy, researchers say. It's estimated that about half of those who undergo chemotherapy for cancer develop what's often called "chemo brain." For instance, they may have trouble following conversations or remembering the steps in a project, according to background notes with the new study. Although usually mild, these changes can affect quality of life, job performance and relationships, said the researchers from the Eastern Maine Medical Center and Lafayette Family Cancer Center in Bangor, Maine. The researchers developed a cognitive-behavioral therapy (CBT) program called Memory and Attention Adaptation Training to help cancer survivors prevent or manage these memory problems. Their study involved 47 breast cancer survivors who underwent ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Prostate Cancer, Fluorouracil, Gleevec, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Skin Cancer, Melanoma, Xeloda, Ovarian Cancer, Tasigna, Endometrial Cancer, Sprycel, Pancreatic Cancer

Exelixis Announces FDA Approval of Cabometyx (cabozantinib) for Patients with Advanced Renal Cell Carcinoma

Posted 27 Apr 2016 by Drugs.com

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Apr. 25, 2016-- Exelixis, Inc. (NASDAQ:EXEL) today announced that the U.S. Food and Drug Administration (FDA) has approved Cabometyx (cabozantinib) tablets for the treatment of patients with advanced renal cell carcinoma (RCC) who have received prior anti-angiogenic therapy. RCC is the most common form of kidney cancer in adults. Cabometyx, which was granted Fast Track and Breakthrough Therapy designations by the FDA, is the first therapy to demonstrate in a phase 3 trial for patients with advanced RCC, robust and clinically meaningful improvements in all three key efficacy parameters — overall survival, progression-free survival and objective response rate. “With today’s announcement, patients with previously treated advanced kidney cancer now have a new option, the first and only approved product demonstrated to help patients live longer w ... Read more

Related support groups: Renal Cell Carcinoma, Cabometyx, Cabozantinib

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medroxyprogesterone, Votrient, Avastin, Sutent, Opdivo, Afinitor, Nexavar, capecitabine, nivolumab, view more... pazopanib, sunitinib, erlotinib, everolimus, sorafenib, Lenvima, Cabometyx, bevacizumab, Proleukin, Inlyta, aldesleukin, Torisel, lenvatinib, cabozantinib, axitinib, temsirolimus, peginterferon alfa-2b, interferon alfa-2a, Mvasi