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Monkey Study Hints at Drug-Free Suppression of HIV

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Scientists may have found a way to suppress an HIV-like infection in monkeys, without the need for ongoing drug therapy. The researchers added antibody therapy to standard drug treatment given to macaque monkeys infected with simian immunodeficiency virus (SIV). After three months, the animals were taken off the drugs, but their viral levels remained low to undetectable – for close to two years. Experts stressed that the animal findings need to be viewed with caution, and that many questions remain. But, they were also hopeful this could lead to a therapy that frees at least some people from their HIV drug regimens. An initial safety study has already started at the U.S. National Institute of Allergy and Infectious Diseases (NIAID). The drug "cocktails" used to treat HIV – known as combined antiretroviral therapy (ART) – have changed the face of the ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Ribavirin, Valacyclovir, Incivek, Zovirax, Baraclude, Famciclovir, Victrelis, Famvir, Viread, Kaletra, Norvir, Entecavir, Tenofovir, Ribasphere, Copegus, Diagnosis and Investigation, Valcyte

Mixed Progress in Worldwide Fight Against HIV/AIDS

Posted 19 Jul 2016 by Drugs.com

TUESDAY, July 19, 2016 – The number of HIV/AIDS deaths worldwide each year has fallen since peaking in 2005, but the number of new HIV infections is up in 74 countries, according to a new study. Deaths from HIV/AIDS fell to 1.2 million in 2015 from 1.8 million in 2005. Though the number of new HIV infections has decreased since a peak of 3.3 million in 1997, it has been relatively stable at about 2.5 million a year for the past decade. Worldwide, new HIV infections fell just 0.7 percent a year between 2005 and 2015, compared to 2.7 percent a year between 1997 and 2005, the study found. Sub-Saharan Africa continued to be a trouble spot, accounting for three-quarters of new HIV infections (1.8 million) in 2015. Last year, south Asia had 8.5 percent (212,500) of new infections; southeast Asia, 4.7 percent (117,500); and east Asia, 2.3 percent (57,500). Between 2005 and 2015, the ... Read more

Related support groups: Infections, HIV Infection, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Baraclude, Victrelis, Viread, Kaletra, Oseltamivir, Tenofovir, Entecavir, Norvir, Telaprevir, Nevirapine, Lamivudine, Boceprevir, Prezista, Reyataz, Tivicay

HIV Infection Seems to Affect Nervous System

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – Many newly infected HIV patients experience neurological problems, but they tend to be mild and they subside after antiretroviral drugs are given, a new study finds. "We were surprised that neurologic findings were so pervasive in participants diagnosed with very recent HIV infection," said study author Dr. Joanna Hellmuth. She is a clinical fellow in the department of neurology at the University of California, San Francisco (UCSF). "While the findings were mild, it is clear that HIV affects the nervous system within days of infection," she said in a university news release. "Since the majority of these neurologic issues were resolved with treatment, our study reinforces recommendations that people at risk for HIV test often and start antiretroviral treatment immediately if they are infected," Hellmuth added. Among 139 people in Thailand infected with HIV three ... Read more

Related support groups: Peripheral Neuropathy, Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Autonomic Neuropathy, Baraclude, Victrelis, Genvoya, Zepatier, Viread, Viekira Pak, Kaletra, Norvir, Daklinza

HIV Decline Falls Short of U.S. 5-Year Goal

Posted 6 May 2016 by Drugs.com

FRIDAY, May 6, 2016 – Although HIV infection and transmission rates in the United States declined over the past five years, they fell short of White House targets, a new study finds. Between 2010 and 2015, new HIV infections decreased 11 percent and transmission of the AIDS-causing virus declined 17 percent, far less than the goals set in 2010 as part of the U.S. National HIV/AIDS Strategy (NHAS), researchers said. The NHAS goals for 2015 were reductions of 25 percent for new HIV infections and 30 percent declines in HIV transmission. "Even though we missed the goals by a sizable margin, it's promising to see that we made important progress in reducing rates of HIV infection and transmission," said lead study author Robert Bonacci. He is a fourth-year medical student at the University of Pennsylvania Perelman School of Medicine. The aim was to lower the persistent HIV infection rate ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Genvoya, Zepatier, Viread, Viekira Pak, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir

Prenatal Use of HIV Drug May Slow Child's Development Slightly

Posted 23 Feb 2016 by Drugs.com

TUESDAY, Feb. 23, 2016 – A drug used to prevent mother-to-child HIV transmission during pregnancy may slow language development slightly in children, a new study suggests. Researchers followed more than 900 infants who were born to HIV-positive mothers but were not infected by the AIDS-causing virus. All of the mothers took antiretroviral drugs during pregnancy. Some of the treatment regimens included a drug called atazanavir (Reyataz), while others did not. The infants underwent a standard test of development at 1 year of age. The 167 infants whose mothers took atazanavir during pregnancy had slightly lower language and social development scores than the 750 infants whose mothers did not take the drug. But the study only showed an association between atazanavir and language delays in children, and did not prove a cause-and-effect link. And the difference in social development scores ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Genvoya, Viread, Viekira Pak, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir, Lamivudine

Alcohol More Harmful for People With HIV, Study Suggests

Posted 9 Feb 2016 by Drugs.com

MONDAY, Feb. 8, 2016 – Drinking alcohol may be more dangerous for people infected with HIV, a new study suggests. The effects of alcohol appear to be more pronounced for those with the virus that causes AIDS, even when the virus is suppressed with modern antiretroviral treatment (ART), the Yale University researchers reported. They noted that HIV patients who have just one or two drinks a day are at greater risk for death or alcohol-related health issues. The study involved patients treated by the U.S. Department of Veterans Affairs between 2008 and 2012. There were more than 18,000 HIV-positive patients and over 42,000 people not infected with the virus. The researchers investigated the link between drinking alcohol, death and other health issues the patients developed. They found the patients with HIV who drank even moderate amounts of alcohol were more likely to develop ... Read more

Related support groups: HIV Infection, Alcohol Dependence, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Alcoholism, Hangover, Baraclude, Victrelis, Viread, Kaletra, Oseltamivir, Tenofovir, Entecavir, Norvir, Telaprevir, Boceprevir, Nevirapine, Prezista, Lamivudine

CDC: Black Americans With HIV Still Less Likely to Get Ongoing Medical Care

Posted 5 Feb 2016 by Drugs.com

FRIDAY, Feb. 5, 2016 – While HIV diagnoses dropped significantly over the past decade in the United States, blacks with HIV are less likely than whites or Hispanics to receive routine, ongoing care, according to the U.S. Centers for Disease Control and Prevention. From 2005 to 2014, annual HIV diagnoses fell 19 percent in the United States. Infections among black women dropped 42 percent during this period. Despite this progress in the fight against HIV, racial disparities persist, the CDC found. While black people make up 12 percent of the U.S. population, they accounted for nearly half of all HIV diagnoses in 2014. "CDC has been working for many years to eliminate the HIV disparities that exist within the black community," Dr. Eugene McCray, director of the CDC's Division of HIV/AIDS Prevention, said in an agency news release. "While we are seeing signs of success, we must continue ... Read more

Related support groups: Harvoni, HIV Infection, Tamiflu, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Genvoya, Viread, Viekira Pak, Oseltamivir, Kaletra, Norvir, Entecavir, Tenofovir

HIV Can Persist in Body Despite Drug Therapy

Posted 27 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – Even when blood tests of HIV patients on antiretroviral drugs show no sign of the AIDS-causing virus, it can still be replicating in lymphoid tissue, researchers report. The study offers important new insight into how HIV persists in the body despite treatment with the powerful drugs, according to the team of international researchers led by Northwestern University's Feinberg School of Medicine in Chicago. To reach their finding, they examined viral sequences in samples of lymph node and blood cells from three HIV-infected patients who had no detectable virus in their blood. And what they found was that a viral reservoir in lymphoid tissue, which scientists believed held long-lived infected cells in a resting state, was being constantly replenished with infected cells. "The challenge is to deliver drugs at clinically effective concentrations to where the ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Genvoya, Sofosbuvir, Viread, Viekira Pak, Kaletra, Diagnosis and Investigation, Norvir, Daklinza

New HIV Treatment Shows Promise in Early Research

Posted 23 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 23, 2015 – Preliminary new research raises the prospect that a recently discovered antibody – an important component of the immune system – could be enlisted to boost the body's response to HIV, the virus that causes AIDS. A single injection of the antibody, currently dubbed VRC01, dramatically reduced the level of HIV in the blood of people who hadn't yet been given antiretroviral drug treatment (ART). ART is the current standard treatment for managing HIV infections, according to the study's authors from the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases in Bethesda, Md. But in people who'd already been treated with ART, the antibody injection had no effect on HIV levels, presumably because the ART therapy had already reduced the levels of HIV virus in their blood, the researchers said. And the researchers were quick to note ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Tamiflu, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Viread, Oseltamivir, Kaletra, Norvir, Tenofovir, Ribasphere, Entecavir

FDA Lifts Ban on Blood Donations by Gay Men

Posted 21 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Gay and bisexual men who have abstained from sex for one year will now be allowed to donate blood in the United States. The new policy, announced Monday by the U.S. Food and Drug Administration, reverses a three-decades-old ban on donations from this group of men that traces back to the start of the AIDS epidemic. "The FDA's responsibility is to maintain a high level of blood product safety for people whose lives depend on it," FDA Acting Commissioner Stephen Ostroff said in an agency news release. "We have taken great care to ensure this policy revision is backed by sound science and continues to protect our blood supply." The FDA said it was changing its policy based on data from other countries that show allowing such donations would not increase the risk of HIV-tainted blood entering America's blood supply. FDA officials have estimated that about half of the ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Harvoni, HIV Infection, Valtrex, Anemia, Acyclovir, Tamiflu, Atripla, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Blood Transfusion, Zovirax, Truvada, Stribild, Triumeq, Complera, Baraclude

Risky Sexual Behaviors Put Many Young Gay Men at Risk of HIV: Study

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Young American gay and bisexual men who have detectable blood levels of HIV – the virus that causes AIDS – are also more likely to engage in risky sexual behavior that might spread the virus, a new study has found. "While many of these young men are engaged in care, and success stories are many, we still have work to do to reduce the rate of new infections," study author Patrick Wilson, an assistant professor of sociomedical sciences at Columbia University's Mailman School of Public Health in New York City, said in a university news release. Different strategies to help prevent HIV infections and promote safe sex are needed for this group, his team wrote in the Dec. 7 issue of the journal JAMA Pediatrics. According to the researchers, young men between the ages of 13 and 29 who are gay or bisexual are particularly vulnerable to infection with HIV and now ... Read more

Related support groups: Birth Control, Contraception, Emergency Contraception, Harvoni, HIV Infection, Postcoital Contraception, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Viread, Viekira Pak, Kaletra, Norvir, Entecavir

HIV Rates Fall, But Not All Groups Benefit, U.S. Study Finds

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – The number of Americans diagnosed with HIV each year declined by about one-fifth during the past decade, but not all groups saw drops in prevalence, a federal government study shows. Between 2005 and 2014, the overall annual number of HIV diagnoses fell 19 percent – from nearly 48,800 to just over 39,700 a year. The drop was led by a 63 percent decline among injection drug users, a 42 percent drop among black women, and a 35 percent decrease among heterosexuals. However, annual HIV diagnoses among gay and bisexual men actually rose about 6 percent during the study period, from about 25,000 to just over 26,600 a year, although they recently stabilized at less than a 1 percent increase a year. The increase in HIV diagnoses among gay and bisexual men was driven largely by blacks and Hispanics, the U.S. Centers for Disease Control and Prevention report found. HIV ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Viread, Viekira Pak, Kaletra, Norvir, Tenofovir, Entecavir, Diagnosis and Investigation, Telaprevir, Ledipasvir/sofosbuvir, Combivir

Charlie Sheen: I'm HIV-Positive

Posted 17 Nov 2015 by Drugs.com

TUESDAY, Nov. 17, 2015 – Actor Charlie Sheen acknowledged Tuesday that he is infected with HIV, the virus that causes AIDS. "It's a hard three letters to absorb. It's a turning point in one's life," Sheen, who is 50, said during an interview on NBC's Today show with co-host Matt Lauer. Sheen said he was diagnosed about four years ago and was going public now for two reasons: to end an extortion campaign that he claimed has cost him millions of dollars and to help combat the stigma of HIV. "I have to put a stop to this onslaught, this barrage of attacks and of sub-truths and very harmful and mercurial stories that are about me, threatening the health of so many others that couldn't be further from the truth," he said of the extortion efforts. Sheen said he initially shared the diagnosis with people he thought he could trust, but has since paid out roughly $10 million to keep his ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Incivek, Baraclude, Victrelis, Viread, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir, Boceprevir, Reyataz, Nevirapine, Prezista, Lamivudine, Hepsera, Abacavir, Ritonavir, Tivicay

Reports Say Charlie Sheen HIV-Positive

Posted 16 Nov 2015 by Drugs.com

MONDAY, Nov. 16, 2015 – Actor Charlie Sheen is reportedly HIV-positive and will discuss the diagnosis Tuesday morning on NBC's Today show, according to multiple published reports. People magazine reported Monday afternoon that individuals close to Sheen approached Hollywood publicist and crisis manager Howard Bragman six months ago on ways to deal with the matter, but Bragman said he never dealt directly with Sheen. "The interview could open up a lot of sympathy for him, but he has to be concerned about a fear of litigation from former sexual partners. You don't take that lightly," Bragman told the magazine. He added that the 50-year-old Sheen "is getting treatment, and a lot of people in his life know about it." Sheen has a history of substance abuse and has admitted to soliciting prostitutes in the past, People reported. "It's been going on for quite a while. He's not necessarily ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Incivek, Baraclude, Victrelis, Viread, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir, Boceprevir, Reyataz, Nevirapine, Prezista, Lamivudine, Hepsera, Abacavir, Ritonavir, Tivicay

HIV Therapy May Also Lower Risk for Hepatitis B, Study Says

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – Not only does effective HIV therapy thwart the AIDS-causing virus, it may also reduce the risk for hepatitis B infection, a new study says. "What this means to us is that effective HIV therapy appears to restore an impairment in the immune response that protects someone with HIV from acquiring hepatitis B infection," study senior author Dr. Chloe Thio, a professor of medicine at Johns Hopkins University School of Medicine, said in a university news release. The study, published in the October issue of Annals of Internal Medicine, involved 2,400 gay and bisexual men who were enrolled in the Multicenter AIDS Cohort Study. Researchers found that the men successfully treated with HIV therapy had the same risk for hepatitis B infection as the men who did not have HIV. Hepatitis B is a virus that can damage the liver. The study showed HIV-positive men on HIV therapy ... Read more

Related support groups: Harvoni, HIV Infection, Valtrex, Acyclovir, Atripla, Hepatitis B, Ribavirin, Sovaldi, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Truvada, Pegasys, Stribild, Complera, Triumeq, Baraclude, Victrelis, Famciclovir

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