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Posted 10 Mar 2016 by Drugs.com
WEDNESDAY, March 9, 2016 – A combination drug therapy widely used to treat malaria in adults also protects pregnant women and their fetuses from the disease, according to a new study. Malaria is a leading cause of premature birth, low birth weight and death among infants in Africa, the researchers said. Most Africans develop immunity to malaria by adulthood, but women lose some of this immunity during pregnancy and are given drugs to prevent infection. The recommended preventive drug is sulfadoxine-pyrimethamine (SP), but the mosquito-transmitted parasite that causes malaria is often resistant to it. Researchers assessed whether the combination therapy dihydroartemisinin-piperaquine (DP) – commonly used to treat malaria in adults – could prevent malaria in pregnant women. The study included 300 pregnant women in Uganda. Beginning in the 16th week of pregnancy, about one-third of the ... Read more
Posted 1 Dec 2015 by Drugs.com
A low-cost alternative to the infection-fighting drug Daraprim will be available to patients as soon as next week. The price of Daraprim rose 5,000 percent after it was acquired by Turing Pharmaceuticals earlier this year. The drug is used to treat a parasitic infection called toxoplasmosis. On Tuesday, Imprimis Pharmaceuticals announced it found a backer to distribute a $1-per-pill alternative to the $750-a-pill Daraprim. The backer is Express Scripts, the largest pharmacy benefits management company in the United States, CNN reported. The active ingredient in Daraprim is pyrimethamine. The new drug is a compound of pyrimethamine and leucovorin. Express Scripts said it will collaborate with medical groups to educate doctors about the new drug, CNN reported. Read more
Posted 24 Jun 2015 by Drugs.com
WEDNESDAY, June 24, 2015 – The Ebola epidemic in West Africa appears to have led to an increase in malaria deaths last year, a new study finds. Research in Guinea, one of the countries hardest hit by the Ebola epidemic, indicates an extra 74,000 cases of malaria went untreated in 2014, compared to previous years. As a result, deaths associated with malaria (a mosquito-borne disease) also rose and will likely exceed Ebola deaths in Guinea, researchers reported June 23 in The Lancet Infectious Diseases. "One problem is that the early symptoms of malaria [fever, headache and body aches] mimic those of Ebola virus disease," said study author Dr. Mateusz Plucinski, from the U.S. Centers for Disease Control and Prevention. "Malaria is one of the main causes of fever and health facilities visits in Guinea, but our data suggest that since the start of the Ebola epidemic, people with fevers ... Read more
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