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Drug May Calm Agitation in Alzheimer's Patients

Posted 22 Sep 2015 by Drugs.com

TUESDAY, Sept. 22, 2015 – A drug that combines a cough suppressant with a heart medication might offer a safer option for calming the agitation that commonly affects people with Alzheimer's disease, an early clinical trial suggests. The study, of 220 Alzheimer's patients, found that the drug – called Nuedexta – generally eased agitation symptoms over 10 weeks. And it did not worsen patients' problems with memory, thinking and judgment, researchers reported in the Sept. 22/29 issue of the Journal of the American Medical Association. As Alzheimer's disease progresses, people often go through periods of agitation that can range from restlessness and pacing to aggressive behavior like yelling, fighting and destroying objects. If those issues can be managed without medication, that's always best, said Dr. Sam Gandy, a professor of neurology and psychiatry at Mount Sinai Hospital, in New ... Read more

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