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Anesthesia Safe for Infants, Toddlers, Study Says

Posted 7 Jun 2016 by Drugs.com

TUESDAY, June 7, 2016 – General anesthesia doesn't seem to harm young children's mental development, new research concludes. "A number of animal studies have suggested that exposure to commonly used anesthetic agents in early development could lead to deficits in learning, memory, attention and other cognitive functions," said study author Dr. Lena Sun. She is a professor of pediatric anesthesiology and pediatrics at Columbia University Medical Center in New York City. "However, few clinical studies have adequately addressed whether this is also true in humans," Sun said in a Columbia news release. The new study findings are "good news for parents whose children need anesthesia for elective surgery or a diagnostic procedure," she added. Still, the study leaves some important questions unanswered, Sun said. "We need to take a closer look at the effect of anesthesia on cognitive function ... Read more

Related support groups: Lidocaine, Anesthesia, Propofol, Ketamine, Light Sedation, Xylocaine, Bupivacaine, Local Anesthesia, Marcaine, Diprivan, Novocain, Septocaine, Nitrous Oxide, Procaine, Light Anesthesia, Sevoflurane, Mepivacaine, Tetracaine, Isoflurane, Prilocaine

Joan Rivers Died from Complications Under Propofol, Coroner Rules

Posted 17 Oct 2014 by Drugs.com

THURSDAY, Oct. 16, 2014 – Joan Rivers has died of "therapeutic complications" while undergoing a procedure to evaluate vocal and gastrointestinal issues, according to the New York medical examiner. The death was caused by a lack of oxygen to the brain during a laryngoscopy, a procedure to view the vocal chords, and an upper gastrointestinal endoscopy. She was sedated with the drug propofol, the medical examiner said. The medical examiner ruled that the cause of death was "anoxic encephalopathy due to hypoxic arrest," which is described as brain damage caused by a lack of oxygen. The classification of a death as a therapeutic complication means that the death resulted from a predictable complication of medical therapy. Propofol, also known under the brand name Diprivan was the same drug under which the entertainer Michael Jackson controversially died in 2009. Rivers, 81, was ... Read more

Related support groups: Propofol, Diprivan, Propoven

Anesthesia Complications Drop by Half, Study Finds

Posted 12 Oct 2014 by Drugs.com

SUNDAY, Oct. 12, 2014 – Anesthesia-related complications in the United States have fallen by more than half, while the overall death rate has remained the same, a new study indicates. Researchers analyzed data from more than 3.2 million cases of anesthesia use between 2010 and 2013, and found the rate of complications decreased from 11.8 percent to 4.8 percent. The most common minor complication was nausea and vomiting (nearly 36 percent) and the most common major complication was medication error (nearly 12 percent). "Our goal was to determine the nature and incidence of surgical complications at the national level and to identify their risk factors," study author Dr. Jeana Havidich, an associate professor of anesthesiology at Dartmouth-Hitchcock Medical Center in New Hampshire, said in an ASA news release. "Previous studies examined adverse events for specific surgical procedures, ... Read more

Related support groups: Anesthesia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

Anesthesia Type May Affect Recovery From Hip Fracture Repair

Posted 24 Jun 2014 by Drugs.com

TUESDAY, June 24, 2014 – Hip fracture surgery patients who are given regional anesthesia have a slightly lower risk of death and a slightly shorter hospital stay than those who receive general anesthesia, a new study shows. Regional anesthesia involves delivery of anesthesia directly to the affected part of the body without putting the patient "to sleep." Researchers analyzed data from nearly 57,000 patients over age 50 who had hip fracture surgery in New York State between 2004 and 2011. Of those patients, 28 percent had regional anesthesia and 72 percent had general anesthesia. The death rate after 30 days was 5.3 percent for regional anesthesia patients and 5.4 percent for general anesthesia patients, which is not statistically significant. The average length of hospital stay was six days for regional anesthesia patients and 6.3 days for general anesthesia patients. The findings ... Read more

Related support groups: Hip Replacement, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Pentothal, Etomidate, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methoxyflurane

FDA Medwatch Alert: Propofol Injectable Emulsion, USP by Hospira: Recall - Visible Particulates

Posted 18 Apr 2014 by Drugs.com

ISSUE: Hospira notified the public of a nationwide recall of seven lots of Propofol Injectable Emulsion, 1%, 200 mg/20 mL (10 mg/mL) to the user level due to a glass defect located on the interior neck of the vial. The defect was identified during a sample inspection where the glass vial contained visible embedded metal particulate. Free-floating metal particulates were also identified in vials upon further analysis. Injected particulate matter may result in local inflammation, phlebitis, and/or low level allergic response through mechanical disruption of tissue or immune response to the particulate. Capillaries, which may be as small as the size of a red blood cell, may become occluded. Chronically, following sequestration, particulate matter may lead to granulomatous formation, most likely in the lungs. Long term clinically meaningful impact is low if a patient has normal lung ... Read more

Related support groups: Anesthesia, Propofol, Diprivan, Propoven

Type of Surgical Anesthesia Might Influence Prostate Cancer's Return

Posted 17 Dec 2013 by Drugs.com

TUESDAY, Dec. 17, 2013 – For men having prostate cancer surgery, the type of anesthesia doctors use might make a difference in the odds of the cancer returning, a new study suggests. Researchers found that of nearly 3,300 men who underwent prostate cancer surgery, those who were given both general and regional anesthesia had a lower risk of seeing their cancer progress than men who received only general anesthesia. Over a period of 15 years, about 5 percent of men given only general anesthesia had their cancer recur in their bones or other sites, the researchers said. That compared with 3 percent of men who also received regional anesthesia, which typically meant a spinal injection of the painkiller morphine, plus a numbing agent. None of that, however, proves that anesthesia choices directly affect a prostate cancer patient's prognosis. "We can't conclude from this that it's ... Read more

Related support groups: Prostate Cancer, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

General Anesthesia Not Linked to Raised Risk for Dementia

Posted 1 May 2013 by Drugs.com

WEDNESDAY, May 1 – Despite previous concerns, older people who receive general anesthesia are not at greater risk of developing long-term dementia or Alzheimer's disease, a new study says. The study, by researchers from the Mayo Clinic in Rochester, Minn., involved 900 patients over the age of 45 who had dementia, a disease that affects brain functions such as memory, language, problem-solving and attention. All of the participants were residents of Olmsted County, Minn., from 1985 to 1994. These patients were compared to other people of similar ages living in the area who did not develop dementia during that time frame. About 70 percent of the study participants in both groups underwent surgery that required general anesthesia. Among patients who had already been diagnosed with dementia, there were no signs that their symptoms got worse due to receiving general anesthesia. Among those ... Read more

Related support groups: Dementia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

More Health Care Professionals Abusing Anesthesia Drug: Study

Posted 26 Mar 2013 by Drugs.com

TUESDAY, March 26 – Abuse of the anesthesia drug propofol by health care professionals is a growing problem, a new study says. Propofol (Diprivan) is used to put patients to sleep for surgery and to sedate them for other procedures. It is widely used because it takes effect rapidly and offers patients a quick recovery time, with fewer side effects than other anesthetics. It was among the mix of drugs that contributed to singer Michael Jackson's death in 2009, the Los Angeles County coroner concluded. Researchers analyzed data from an addiction center specializing in substance abuse problems among health care professionals and identified 22 health care workers who were treated for propofol abuse between 1990 and 2010. During that period, there was a steady increase in the number of health care professionals treated for propofol abuse, which currently accounts for 1.6 percent of all ... Read more

Related support groups: Propofol, Ketamine, Substance Abuse, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

Accidental Awareness During Anesthesia Is Rare, Study Finds

Posted 12 Mar 2013 by Drugs.com

TUESDAY, March 12 – Very few surgical patients experience accidental awareness while under general anesthesia, according to a new study. The Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland surveyed all senior anesthetists at National Health Service hospitals in the United Kingdom, asking them how many cases of accidental awareness during general anesthesia they encountered in 2011. Previous research has suggested a high rate of accidental awareness, occurring in about one in 500 patients. But this study found that the rate was one in 15,000. The researchers also found that only about 2 percent of anesthetists routinely use brain-monitoring equipment to keep tabs on patients during surgery. The findings, published in the journals Anesthesia and The British Journal of Anaesthesia, appeared online March 12. "Anesthesia is a medical ... Read more

Related support groups: Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Pentothal, Etomidate, Thiopental, Amidate, Ethrane, Terrell, Fospropofol, Forane, Ultane PEN, Propoven, Ketalar, Methoxyflurane

Secret of Anesthesia Revealed, Study Says

Posted 25 Oct 2012 by Drugs.com

THURSDAY, Oct. 25 – General anesthesia drugs really do put patients to sleep, suggests research conducted in mice. The study found that the drugs don't just turn wakefulness off, they also switch on important sleep circuits in the brain, according to the findings, which were published online Oct. 25 in the journal Current Biology. "Despite more than 160 years of continuous use in humans, we still do not understand how anesthetic drugs work to produce the state of general anesthesia," Dr. Max Kelz, an anesthesiologist at the University of Pennsylvania, said in a journal news release. "We show that a commonly used inhaled anesthetic drug directly causes sleep-promoting neurons to fire," Kelz said. "We believe that this result is not simply a coincidence. Rather, our view is that many general anesthetics work to cause unconsciousness in part by recruiting the brain's natural sleep ... Read more

Related support groups: Anesthesia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

Survival After General Anesthesia Vastly Improved: Study

Posted 20 Sep 2012 by Drugs.com

THURSDAY, Sept. 20 – The number of people who survive surgery when general anesthesia is used has improved dramatically over the past 50 years, Canadian researchers report. The improvement was noted worldwide, with most of the increases in survival seen in developed countries, the researchers added. Overall, there was a 90 percent drop in such deaths since before the 1970s. "Anesthesia safety continues to improve, and we should continue to find ways to make it even safer," said lead researcher Dr. Daniel Bainbridge, from the department of anesthesia and perioperative medicine at the University of Western Ontario. "We have done a good job to reduce risk of anesthesia," he said. "However, it is similar to the airline industry in that passengers tend to be very concerned about dying while flying, likewise they also are concerned about dying [while] under anesthesia, so the question is ... Read more

Related support groups: Anesthesia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

Anesthesia Before Age 3 May Raise Risk of Learning Delays: Study

Posted 20 Aug 2012 by Drugs.com

MONDAY, Aug. 20 – Children younger than 3 who have even one surgical procedure requiring general anesthesia may be more likely to have deficits in language and abstract reasoning at age 10, a new study suggests. Australian researchers gave neuropsychological tests to more than 2,600 children; a little more than 300 were exposed to anesthesia before the age of 3 and nearly 2,300 were not. The tests measured language, cognitive function, motor skills and behavior at age 10. Previous studies have relied on parent or teacher assessments, standardized tests and school grades to assess learning delays in children exposed to anesthesia. "Children who were exposed to anesthesia had lower scores in language and abstract reasoning at age 10," said study author Dr. Caleb Ing, a pediatric anesthesiologist at Columbia University College of Physicians and Surgeons in New York City. Even a single ... Read more

Related support groups: Anesthesia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

FDA Medwatch Alert: Hospira Propofol Injectable Emulsion: Recall - Glass Vial Defect

Posted 17 Aug 2012 by Drugs.com

ISSUE: Hospira and FDA notified healthcare professional of a nationwide recall of three lots of Propofol Injectable Emulsion, 1%, 1g/100 mL, due to visible particles embedded in the glass to the user level. There may be potential for product to come into contact with the embedded particles and the particles may become dislodged into the solution. In the event in which particulate matter could be injected into a patient, there may be the potential for patient injury where medical intervention may be required. Risks associated with this defect could include tissue necrosis in one or more organsthat could result in stroke, myocardial infarction, respiratory failure, and loss of renal and hepatic function. See the Press Release for a listing of affected product lot numbers and expiration dates. BACKGROUND: The product is packaged in vials and indicated for the induction or maintenance of ... Read more

Related support groups: Anesthesia, Propofol, Diprivan, Propoven

Anesthesia in Early Childhood May Be Linked to ADHD

Posted 2 Feb 2012 by Drugs.com

THURSDAY, Feb. 2 – Children who have more than one surgery with general anesthesia by their second birthday might be at higher risk for attention-deficit/hyperactivity disorder (ADHD), a new study suggests. Mayo Clinic researchers looked through medical records of 341 children diagnosed with ADHD before age 19, to find who had undergone a surgical procedure with anesthesia before they were 2. Nearly 18 percent of children exposed twice or more eventually developed ADHD. Children with only one exposure had an ADHD rate of nearly 11 percent, while never-exposed children had a rate of slightly more than 7 percent. The researchers also looked at anesthesia given to mothers during childbirth. "With Cesarean section with a general anesthetic, only a single anesthetic, we didn't find any effect," said study author Dr. Juraj Sprung, a professor of anesthesiology at the Mayo Clinic. The study ... Read more

Related support groups: Attention-Deficit Hyperactivity Disorder (ADHD), Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Halothane, Droperidol, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Lusedra, Ketalar, Methohexital

Obese, Asthmatic Kids Need Special Care Under Anesthesia

Posted 19 Oct 2011 by Drugs.com

WEDNESDAY, Oct. 19 – Obese children need special attention when they undergo anesthesia, two new studies suggest. In one study, researchers found that obese children with asthma suffer more complications from anesthesia than normal weight children with asthma. In the other study, researchers found that obese children require less of one type of anesthesia than normal weight kids. If a child is obese, has asthma or both, parents should expect close monitoring, said researcher Dr. Olubukola Nafiu, an assistant professor of pediatric anesthesiology at the University of Michigan. "Children who are obese and asthmatic have a twofold increased risk of developing respiratory problems when they are given anesthesia," Nafiu said. Both studies are scheduled for presentation Monday at the annual meeting of the American Society of Anesthesiologists in Chicago. To determine if complications were ... Read more

Related support groups: Obesity, Asthma, Anesthesia, Propofol, Ketamine, Diprivan, Nitrous Oxide, Isoflurane, Sevoflurane, Droperidol, Halothane, Etomidate, Pentothal, Thiopental, Amidate, Ethrane, Terrell, Forane, Ultane PEN, Ketalar

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