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Pfizer Receives FDA Approval for Prevnar 13 in Adults Age 18 Through 49

Posted 21 Jul 2016 by Drugs.com

July 12, 2016 - Pfizer Inc. (NYSE:PFE) today announced that Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) received U.S. Food and Drug Administration (FDA) approval for an expanded age indication to include adults 18 through 49 years of age, in addition to the already approved indication for adults 50 years and older, for active immunization for the prevention of pneumonia and invasive disease caused by 13 Streptococcus pneumoniae (S. pneumoniae) serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F). Prevnar 13 is the only pneumococcal vaccine approved across the lifespan. With today’s decision Prevnar 13 is approved for: Adults 18 years of age and older for the prevention of pneumococcal pneumonia and invasive disease caused by 13 Streptococcus pneumoniae strains in the vaccine Children 6 weeks through 17 years of age (prior to the 18th b ... Read more

Related support groups: Prevnar 13, Pneumococcal Disease Prophylaxis, Pneumococcal 13-valent Conjugate Vaccine

Childhood Vaccinations Rarely Spur Seizures, Study Finds

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Certain vaccines can trigger fever-related seizures in young children, but the risk is so low that pediatricians might see one case every five to 10 years, a new study estimates. It has long been known that some vaccines carry a small seizure risk. But the researchers said the new report offers some hard numbers. And it suggests that even when babies and toddlers get three vaccines at once, they only develop fever-related seizures at a rate of 30 per 100,000 – at most. The findings should be "reassuring" to parents, said lead researcher Dr. Jonathan Duffy, of the U.S. Centers for Disease Control and Prevention. "Looking at the big picture, the benefits of vaccination are much greater than the risk of febrile [fever-related] seizures," Duffy said. Up to 5 percent of young children will have a fever-related seizure at some point, according to the CDC. It usually ... Read more

Related support groups: Seizures, Fever, Seizure Prevention, BCG, Zostavax, Yellow Fever Vaccine, Gardasil, Prevnar 13, Prevnar, Seizure Prophylaxis, Tetanus Toxoid, Vivotif Berna, Rabies Vaccine, Human Diploid Cell, Typhoid Vaccine, Live, Hepatitis B Adult Vaccine, FluLaval, Vivotif Berna Vaccine, Varicella Virus Vaccine, Twinrix, Smallpox Vaccine

With Flu Shot, Timing May Be Everything

Posted 26 Apr 2016 by Drugs.com

TUESDAY, April 26, 2016 – Flu shots may be more effective when people get them in the morning than in the afternoon, a new study suggests. British researchers assessed 276 people 65 and older who received vaccinations against three different flu strains between 2011 and 2013. The patients received the vaccines either between 9 a.m. and 11 a.m., or 3 p.m. and 5 p.m. People in the morning group had a much larger increase in antibodies against two of the flu strains one month after vaccination, the researchers found. However, with the third flu strain, there was no significant difference between the morning and afternoon groups. "We know that there are fluctuations in immune responses throughout the day and wanted to examine whether this would extend to the antibody response to vaccination," said lead investigator Anna Phillips. She's with the University of Birmingham's School of Sport, ... Read more

Related support groups: Influenza, Prevnar 13, Influenza A, Avian Influenza, FluLaval, Afluria, Pneumococcal 23-polyvalent Vaccine, Pneumovax 23, Fluzone, Pneumococcal Disease Prophylaxis, FluMist, Pneumococcal 13-valent Conjugate Vaccine, Vaccination and Prophlaxis, Flucelvax, Influenza Virus Vaccine, Inactivated, Flushield, Fluzone 2015-2016, FluLaval Quadrivalent, Afluria 2015-2016, Fluvirin Preservative-Free

One in Five Pediatricians Drops Families Who Refuse Vaccines: Survey

Posted 2 Nov 2015 by Drugs.com

MONDAY, Nov. 2, 2015 – One of every five U.S. pediatricians regularly drops families who refuse to have their children vaccinated, a new survey shows. Doctors in the South and Northeast were more likely to take this hardline stance, said study lead author Dr. Sean O'Leary, a pediatric infectious disease specialist at Children's Hospital Colorado in Denver. But O'Leary said he's heard anecdotally that pediatricians across the nation have come under pressure to refuse to take on unvaccinated children, following the Disneyland measles outbreak that occurred earlier this year. "I'm hearing the practice has become more common, particularly in California, following the outbreak," O'Leary said. "Parents say, 'I don't want to take my child to a clinic with non-vaccinators and expose them to risk,' so there is parental pressure on some pediatricians." An ongoing medical debate continues to ... Read more

Related support groups: Hepatitis B Prevention, Pneumococcal Disease Prophylaxis, Meningococcal Meningitis Prophylaxis, Tetanus Prophylaxis, Vaccination and Prophlaxis, Influenza Prophylaxis, Poliomyelitis Prophylaxis, Hepatitis B Prophylaxis, Mumps Prophylaxis, Rubella Prophylaxis, Measles Prophylaxis, Pertussis Prophylaxis, Haemophilus influenzae Prophylaxis

Childhood Vaccines Debate Rekindled at GOP Presidential Debate

Posted 18 Sep 2015 by Drugs.com

THURSDAY, Sept. 17, 2015 – Some parents' long-simmering concerns over the safety of childhood vaccines received unexpected – and, in some quarters, unwelcome – notice during the second Republican presidential candidates' debate. While the link between vaccines and autism has long been discredited, an exchange toward the debate's end addressed a more recent parental concern – whether children are receiving too many vaccines too soon. And the potential fallout from that exchange has infectious-disease experts worried. Candidates Ben Carson and Rand Paul – both doctors – both argued Wednesday night that children probably are receiving too many vaccinations in too short a time, and that parents ought to have the right to deviate from the recommended schedule. The candidates said vaccines are safe and important, and dismissed fears that some vaccines might cause autism, but argued for ... Read more

Related support groups: Autism, Asperger Syndrome, Measles Virus Vaccine, Pneumococcal Disease Prophylaxis, Meningococcal Meningitis Prophylaxis, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Tetanus Prophylaxis, Vaccination and Prophlaxis, Influenza Prophylaxis, Human Papillomavirus Prophylaxis, Poliomyelitis Prophylaxis, ProQuad, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine, Haemophilus influenzae Prophylaxis, Measles Virus Vaccine/Rubella Virus Vaccine, Measles Prophylaxis, Attenuvax, Mumps Prophylaxis, M-R-Vax II, M-M-R II

Start of School Year Calls for Vaccine Check

Posted 21 Aug 2015 by Drugs.com

FRIDAY, Aug. 21, 2015 – With the start of a new school year, many parents are searching for vaccination records and hoping they're current, but what does "up-to-date" look like these days? That depends on whether it's what the school requires or what pediatric experts recommend. "Not all vaccines that we recommend on the schedule are required by schools," said Wendy Sue Swanson, a pediatrician at Seattle Children's Hospital. "But schools help us keep up-to-date and have an annual assessment" of vaccine status. Swanson explained that during childhood, three key school transitions coincide with vaccine schedules. The first, she said, is when a child enters kindergarten. Then, "typically, at sixth grade, we refresh again. And there are updates that we provide kids at the end of high school as get they ready to go to college," she added. Each of these turning points usually means exposure ... Read more

Related support groups: BCG, Zostavax, Yellow Fever Vaccine, Gardasil, Prevnar 13, Prevnar, Tetanus Toxoid, Vivotif Berna, Rabies Vaccine, Human Diploid Cell, Typhoid Vaccine, Live, Hepatitis B Adult Vaccine, FluLaval, Vivotif Berna Vaccine, Twinrix, Varicella Virus Vaccine, Hepatitis B Prevention, Smallpox Vaccine, Rotarix, Pneumococcal 23-polyvalent Vaccine, Measles Virus Vaccine

Doctors Worry About Return of Vaccine-Preventable Ills in Kids

Posted 12 Jun 2015 by Drugs.com

FRIDAY, June 12, 2015 – Although most U.S. children are getting their routine vaccinations, recent trends have experts concerned that Americans will lose some of the "herd immunity" that has long protected many from serious infections. The vast majority of U.S. kids are up-to-date with routine jabs against once-common infections like polio, measles, mumps, whooping cough and chickenpox. But that "coverage" varies from state to state, according to the latest figures from the U.S. Centers for Disease Control and Prevention. In 2013, there were 17 states where less than 90 percent of 1.5- to 3-year-olds had gotten their first dose of the measles-mumps-rubella (MMR) vaccine, the CDC found. And nationally, recent years have seen a small dip in the percentage of young children who are up-to-date with some other vaccines, according to Dr. Mark Sawyer, an infectious disease specialist at Rady ... Read more

Related support groups: Hepatitis B Prevention, Pneumococcal Disease Prophylaxis, Tetanus Prophylaxis, Vaccination and Prophlaxis, Influenza Prophylaxis, Hepatitis B Prophylaxis, Poliomyelitis Prophylaxis, Human Papillomavirus Prophylaxis, Diphtheria Prophylaxis, Rubella Prophylaxis, Measles Prophylaxis, Mumps Prophylaxis, Pertussis Prophylaxis, Haemophilus influenzae Prophylaxis

Infectious-Disease Expert Debunks Common Vaccine Myths

Posted 12 May 2015 by Drugs.com

TUESDAY, May 12, 2015 – A small minority of people still distrust the safety of routine childhood vaccinations, but one expert says the myths that swirl around vaccines are easily dismissed. "Both parents and doctors have the same goal, to keep a child healthy, and the best way to keep a child safe is through vaccination," said Dr. Nadia Qureshi, a pediatric infectious disease specialist at Loyola University Health System in Chicago. According to the U.S. Centers for Disease Control and Prevention, vaccines have saved more than 732,000 lives in the United States over the past two decades. But misconceptions about these simple but crucial health care interventions persist. One major myth is that the measles-mumps-rubella (MMR) vaccine causes autism, said Qureshi, who is also an assistant professor of pediatrics at Loyola University. "This myth began in 1998 when an English surgeon ... Read more

Related support groups: Autism, Measles, Hepatitis B Prevention, Pneumococcal Disease Prophylaxis, Pneumocystis Pneumonia Prophylaxis, Meningococcal Meningitis Prophylaxis, Vaccination and Prophlaxis, Human Papillomavirus Prophylaxis, Influenza Prophylaxis, Poliomyelitis Prophylaxis, Tetanus Prophylaxis, Hepatitis B Prophylaxis, Mumps Prophylaxis, Pertussis Prophylaxis, Herpes Zoster - Prophylaxis, Rubella Prophylaxis, Measles Prophylaxis, Diphtheria Prophylaxis, Haemophilus influenzae Prophylaxis, Hepatitis A Prophylaxis

Seniors Need 2 Pneumonia Vaccines, CDC Advisory Panel Says

Posted 3 Feb 2015 by Drugs.com

TUESDAY, Feb. 3, 2015 – Adults 65 and older need two vaccines to better protect them from bacterial infection in the blood (called sepsis), meningitis and pneumonia, according to a revised vaccination schedule from the 2015 Advisory Committee on Immunization Practices (ACIP). The ACIP is the vaccine advisory panel for the U.S. Centers for Disease Control and Prevention. Such infections are caused by pneumococcal bacteria, and older people have an increased risk of life-threatening infection from these bacteria. "All adults aged 65 years or older should talk to their health care providers about getting pneumococcal vaccines for protection against pneumococcal diseases," said Dr. David Kim, the CDC's deputy associate director for adult immunizations. The new recommendations were published in the Feb. 3 Annals of Internal Medicine. The committee recommended that seniors get both the ... Read more

Related support groups: Prevnar 13, Pneumovax 23, Pneumococcal 23-polyvalent Vaccine, Pneumococcal Disease Prophylaxis, Pneumococcal 13-valent Conjugate Vaccine

Vaccine Opponents Often Cluster in Communities

Posted 19 Jan 2015 by Drugs.com

MONDAY, Jan. 19, 2015 – Parents who refuse to have their children vaccinated appear to be clustered in certain areas, a new study suggests. Among more than 150,000 children in 13 counties in Northern California, the researchers found five clusters where kids had missed one or more vaccinations by the time they were 3 years old. "It's known from other studies that areas where there are clusters of vaccine refusal are at higher risk of epidemics, such as whooping cough epidemics," said lead investigator Dr. Tracy Lieu, a pediatrician and director of the division of research at Kaiser Permanente Northern California, in Oakland. "Clusters may deserve special outreach efforts to make sure parents have all the information they need to make informed decisions about vaccination," she said. Specifically, the researchers found the rate of missed vaccinations within these clusters ranged from 18 ... Read more

Related support groups: Influenza, Tetanus, Swine Influenza, Measles, Pertussis, Rubella, Influenza A, Avian Influenza, Diphtheria, Hepatitis B Prevention, Pneumococcal Disease Prophylaxis, Influenza Prophylaxis, Hepatitis B Prophylaxis, Tetanus Prophylaxis, Poliomyelitis Prophylaxis, Rubella Prophylaxis, Measles Prophylaxis, Diphtheria Prophylaxis, Hepatitis A Prophylaxis, Influenza with Pneumonia

Common Childhood Vaccine Cuts 'Superbug' Infection: Study

Posted 10 Oct 2014 by Drugs.com

FRIDAY, Oct. 10, 2014 – The childhood pneumococcal vaccine helps children avoid the suffering and danger of ear infections, meningitis and pneumonia. And a new study suggests it may provide an added bonus: cutting down on infections from antibiotic-resistant "superbugs." First used in children in 2010, the pneumococcal vaccine was linked to a 62 percent reduction between 2009 and 2013 of drug-resistant infections of bacterial pneumonia, meningitis and bloodstream infections for children under 5. "The vaccine is an important tool against antibiotic resistance," said lead researcher Sara Tomczyk, an epidemic intelligence service officer in the Respiratory Diseases Branch of the U.S. Centers for Disease Control and Prevention. "Along with appropriate antibiotic use, it is part of the solution to protecting ourselves against the growing threat of antibiotic resistance," she added. The ... Read more

Related support groups: Prevnar 13, Prevnar, Pneumococcal 23-polyvalent Vaccine, Pneumovax 23, Pneumococcal Disease Prophylaxis, Pneumococcal 7-Valent Vaccine, Pneumococcal 23-Valent Vaccine, Pneumococcal 13-valent Conjugate Vaccine

Temporary Fever May Occur When Kids Under 2 Get 2 Shots at Once

Posted 7 Jan 2014 by Drugs.com

TUESDAY, Jan. 7, 2014 – Young children who receive flu and pneumococcal vaccines at the same time are at increased risk for temporary fever, a new study reports. While parents should be told about this risk, the benefits of the vaccines outweigh the risks of fever, the researchers said. The study included 530 children, aged 6 months to 23 months, who were followed for a week after receiving flu and pneumococcal vaccines either separately or at the same time. The annual flu shot is recommended for healthy people over 6 months of age, and the pneumococcal vaccine is recommended for children younger than 5 years old, according to the U.S. Centers for Disease Control and Prevention. Nearly 38 percent of the children who received the vaccines at the same time had a fever of 100.4 degrees Fahrenheit or higher on the day of or the day after vaccination, compared with 9.5 percent of those who ... Read more

Related support groups: Fever, Prevnar 13, Prevnar, FluLaval, Pneumococcal 23-polyvalent Vaccine, Afluria, Pneumovax 23, Pneumococcal Disease Prophylaxis, Fluzone, Pneumococcal 23-Valent Vaccine, Pneumococcal 7-Valent Vaccine, Vaccination and Prophlaxis, Pneumococcal 13-valent Conjugate Vaccine, Influenza Prophylaxis, Flucelvax, Influenza Virus Vaccine, Inactivated, Fluvirin, Agriflu, Fluzone PFS, Fluzone SV

Too Few Adults Get Recommended Vaccines: CDC

Posted 29 Jan 2013 by Drugs.com

TUESDAY, Jan. 29 – Vaccines aren't just for kids, and most American adults aren't getting their recommended vaccinations, federal health officials said Tuesday. "In general, too few adults are taking advantage of the protection of vaccines, leaving themselves and those around them at greater risk of vaccine-preventable diseases," Dr. Howard Koh, assistant secretary for health at the U.S. Department of Health and Human Services, said during a news conference. For example, Koh said, in 2011, the most recent year for which data are available, there were some 37,000 cases of preventable pneumococcal pneumonia that resulted in 4,000 deaths. The majority of deaths occurred among adults 50 and older, and the highest rates were seen among those 65 years and older. Almost everyone who gets invasive pneumococcal disease needs treatment in the hospital, and that's why people 65 and older should ... Read more

Related support groups: Gardasil, Prevnar 13, Prevnar, Tetanus Toxoid, Hepatitis B Adult Vaccine, Twinrix, Human Papillomavirus Vaccine, Pneumococcal 23-polyvalent Vaccine, Hepatitis B Prevention, Cervarix, Pneumococcal Disease Prophylaxis, Pneumococcal 23-Valent Vaccine, Havrix, Pneumococcal 7-Valent Vaccine, Vaccination and Prophlaxis, Hepatitis B Prophylaxis, Diphtheria Toxoid/Tetanus Toxoid, Daptacel (DTaP), Tetanus Prophylaxis, Tripedia (DTaP)

Doctors in a Bind When Parents Want to Delay, Skip Vaccines

Posted 28 Nov 2011 by Drugs.com

MONDAY, Nov. 28 – Mistrust of childhood vaccines is causing some parents to request "alternative" schedules from doctors, either delaying or skipping some shots. And a new study suggests that most pediatricians are willing to go along with these requests – up to a point. "Parents seem to be regularly requesting alternative childhood immunization schedules," noted co-author Dr. Douglas John Opel, an acting assistant professor in the University of Washington's department of pediatrics. However, he added, "there needs to be more research into the effectiveness and safety of these schedules." The report is published in the Nov. 28 online edition of Pediatrics. The issue of parents ignoring standard guidelines on childhood vaccination schedules is worrying to many experts. One study, published in the November issue of Pediatrics, found that more than one in 10 parents in the United States ... Read more

Related support groups: Pneumonia, Meningitis, Prevnar 13, Prevnar, Pneumococcal 23-polyvalent Vaccine, Measles Virus Vaccine, Kinrix, Pneumococcal Disease Prophylaxis, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Meningococcal Meningitis Prophylaxis, Pneumococcal 7-Valent Vaccine, ProQuad, Diphtheria Toxoid/Pertussis, Acellular/Poliovirus Vaccine, Inactivated/Tetanus Toxoid, Poliomyelitis Prophylaxis, Meningitis - Meningococcal, Daptacel (DTaP), Vaccination and Prophlaxis, Diphtheria Toxoid/Tetanus Toxoid, Tetanus Prophylaxis, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine

Vaccine Now Misses Many Pneumococcal Infections in Kids

Posted 21 Apr 2010 by Drugs.com

WEDNESDAY, April 21 – The advent in 2000 of the PCV7 vaccine to battle bacteria that causes pneumonia, meningitis and sepsis (blood infection) in children has caused notable changes in strains that cause these illnesses, researchers report. Most worrisome is the recent spread of strains not covered by the vaccine, the team aid. Immunizations with the PCV7 vaccine is now recommended for all children before the age of 2. American researchers found that the most common cause of invasive pneumococcal infections is now a strain called serotype 19A, which is not covered by the PCV7 vaccine. The studies also found a rise in infections caused by antibiotic-resistant pneumococci. One study, an analysis of 2001-07 data by Boston University researchers, revealed that only 15 percent of serious pneumococcal infections in Massachusetts were caused by one of the seven strains covered by the PCV7 ... Read more

Related support groups: Prevnar, Pneumococcal Disease Prophylaxis, Pneumococcal 7-Valent Vaccine

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