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Study Suggests Genetic Link to Middle Ear Infections

Posted 7 Oct 2016 by Drugs.com

FRIDAY, Oct. 7, 2016 – Researchers say they've found a potential genetic link to a child's higher risk of middle ear infections. These painful infections are the most frequent reason kids are given antibiotics, according to the researchers. They said the new discovery could lead to more effective treatments. The analysis of DNA samples from 13,000 children revealed a link between middle ear infection and a site on chromosome 6 that contains the gene FNDC1. Follow-up studies showed that the corresponding gene in mice was expressed in the middle ear. The study was published online recently in the journal Nature Communications. "Although the gene's function in humans has not been well studied, we do know that FNDC1 codes for a protein with a role in inflammation," said study leader Dr. Hakon Hakonarson, director of the Center for Applied Genomics at The Children's Hospital of ... Read more

Related support groups: Otitis Media, Hearing Loss, Diagnosis and Investigation, Otitis Media with Perforation of Ear Drum, Chronic Otitis Media, Perforated Tympanic Membrane

Infant Ear Infections Becoming Less Common

Posted 28 Mar 2016 by Drugs.com

MONDAY, March 28, 2016 – Painful ear infections remain a scourge of childhood, but fewer American babies are getting them now compared with 20 years ago, new research shows. The study didn't dig into the reasons for the decline. But experts say the credit likely goes to certain childhood vaccines, rising rates of breast-feeding and the drop in Americans' smoking rate. The new research found that 46 percent of babies followed during 2008 to 2014 had a middle ear infection by the time they were 1 year old. But while the infections were common, those rates were lower when compared against U.S. studies from the 1980s and '90s, the researchers added. Back then, around 60 percent of babies had suffered an ear infection by their first birthday, the study authors said. The decline is not surprising, according to lead researcher Dr. Tasnee Chonmaitree, a professor of pediatrics at the ... Read more

Related support groups: Otitis Media, Chronic Otitis Media, Tympanostomy Tubes, Otitis Media with Perforation of Ear Drum, Perforated Tympanic Membrane

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