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Parkinson's Disease Psychosis News

Study Hints at Link Between Some Statins, Parkinson's Risk

Posted 7 days ago by Drugs.com

TUESDAY, June 20, 2017 – People on cholesterol-lowering statins may have a slightly increased risk of developing Parkinson's disease, a new study suggests. Researchers said the finding doesn't prove statins are to blame. But, they added, the findings undercut the notion that statins might help protect against Parkinson's. Where does that idea come from? Past research has shown that people with high cholesterol tend to have a lower risk of Parkinson's, explained Dr. Xuemei Huang, a professor of neurology at Penn State College of Medicine. Since many of those people are treated with statins, that led to speculation that the drugs – rather than high cholesterol itself – might be protective. But so far, studies have come to mixed conclusions, according to Huang. Some have tied statins to a lower Parkinson's risk, while others have found either no connection or an increased risk. Enter ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Parkinson's Disease, Atorvastatin, Pravastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Caduet, Simcor, Parkinsonian Tremor, Lescol, Parkinsonism, Lescol XL, Mevacor

Does a Low-Fat Dairy Habit Boost Parkinson's Risk?

Posted 19 days ago by Drugs.com

THURSDAY, June 8, 2017 – Though you might think eating low-fat dairy foods is a healthy move, new research suggests the habit is tied to a slight rise in the risk of developing Parkinson's disease. Experts who reviewed the study stressed that the findings are preliminary – the effect was a modest one and the research wasn't designed to prove cause and effect. In the study, researchers analyzed data on about 130,000 men and women, tracking their dietary habits every four years and the number of people diagnosed with Parkinson's. After 25 years, more than 1,000 people developed Parkinson's, a progressive neurodegenerative illness affecting coordination and movement. Those who consumed at least three servings of low-fat dairy a day had a 34 percent higher risk of getting the disorder than those who only consumed one serving a day. Looking specifically at milk consumption, the researchers ... Read more

Related support groups: Parkinson's Disease, Dietary Supplementation, Vitamin/Mineral Supplementation and Deficiency, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

Black, Hispanic Americans Less Likely to See a Neurologist

Posted 18 May 2017 by Drugs.com

WEDNESDAY, May 17, 2017 – Black and Hispanic people are less likely than white people to make an appointment to see a neurologist, according to a new U.S. study. Researchers found that black people with conditions that affect the brain, such as Parkinson's disease and stroke, tend to be treated in the emergency room and end up in the hospital more often than their white peers. "Our findings demonstrate that there are substantial racial and ethnic disparities in neurologic health care access and utilization in the United States," said study author Dr. Altaf Saadi, from Massachusetts General Hospital and Brigham and Women's Hospital in Boston. "These disparities are concerning, not only because racial and ethnic minorities represent 28 percent of Americans, but because all Americans should have equitable access to health care regardless of who they are, where they live, or what resources ... Read more

Related support groups: Parkinson's Disease, Neurologic Disorder, Parkinsonian Tremor, Parkinsonism, Head Imaging, Parkinson's Disease Psychosis

Study Looks at Parkinson's Effect on Life Span

Posted 15 May 2017 by Drugs.com

MONDAY, May 15, 2017 – People with brain diseases such as Parkinson's and dementia with Lewy bodies die about two years earlier compared with people who don't have these conditions, a new study suggests. The report provides new clues about the survival of patients with degenerative brain diseases, researchers at the Mayo Clinic said. "Our results may be helpful to guide clinicians counseling patients and caregivers," Dr. Rodolfo Savica and colleagues wrote in the report published May 15 in JAMA Neurology. The study initially looked at all residents of Minnesota's Olmsted County. The investigators then compared survival rates between 461 people with certain degenerative brain diseases and 452 healthy people in the general population. The study participants with degenerative brain diseases were diagnosed between 1991 and 2010. Just over 300 had Parkinson's disease; 55 had Parkinson's ... Read more

Related support groups: Parkinson's Disease, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Parkinsonian Tremor, Parkinsonism, Lewy Body Dementia, Parkinson's Disease Psychosis

Parkinson's Disease May Originate in Gut, Study Says

Posted 27 Apr 2017 by Drugs.com

WEDNESDAY, April 26, 2017 – New research suggests additional evidence that Parkinson's disease may originate in the gut. Though experts called the findings preliminary, Swedish scientists found that patients whose main trunk of the vagus nerve – which extends from the brain stem to the abdomen – was removed were markedly less likely to develop the movement disorder than others who didn't have the surgery. The patients were followed for at least five years. The study authors said the findings suggest Parkinson's may start in the gut and spread to the brain through the vagus nerve, which helps control unconscious body processes such as heart rate and digestion. "We were not largely surprised, as other research has also shown evidence for a link between the gut and Parkinson's disease," said study author Dr. Karin Wirdefeldt. She's an associate professor of medical epidemiology and ... Read more

Related support groups: Parkinson's Disease, Diagnosis and Investigation, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

150-Year-Old Drug May Shorten 'Off' Time for Parkinson's Patients

Posted 21 Apr 2017 by Drugs.com

FRIDAY, April 21, 2017 – An old standby drug seems to help patients with advanced Parkinson's disease through the difficult times when their usual medication stops working, a new trial suggests. As the movement disorder progresses, the effectiveness of the usual drug, levodopa, wears off more quickly after each dose, the researchers explained. Patients can experience so-called "off" times, which can result in stiffness and leave them immobilized until the levodopa kicks in again. During these off times, the injectable drug apomorphine (Apokyn) can significantly shorten the period before levodopa takes over, the investigators found. "The results confirm what had been expected based on decades of clinical experience with apomorphine infusion in Europe," said lead researcher Dr. Regina Katzenschlager, a guest professor at the Medical University of Vienna in Austria. "When fluctuations in ... Read more

Related support groups: Parkinson's Disease, Sinemet, Levodopa, Carbidopa/Levodopa, Stalevo, Rytary, Sinemet CR, Parkinsonian Tremor, Stalevo 100, Parkinsonism, Parcopa, Stalevo 200, Carbidopa/Entacapone/Levodopa, APO-Go, Apokyn, Apomorphine, Stalevo 150, Dopar, Stalevo 50, Stalevo 125

Exercising 2.5 Hours a Week May Slow Parkinson's Progression

Posted 29 Mar 2017 by Drugs.com

WEDNESDAY, March 29, 2017 – Parkinson's disease can cause tremors, stiffness and trouble with walking. But a new study suggests that regular exercise can slow the progression of the disease. Even those with advanced Parkinson's can benefit from activity, the study authors said. The research included more than 3,400 patients in North America, the Netherlands and Israel who were followed for more than two years. During that time, Parkinson's-related changes in mobility were assessed by timing how long it took patients to rise from a chair, walk about 10 feet, turn and return to a sitting position. The results were published online recently in the Journal of Parkinson's Disease. "We found that people with Parkinson's disease who maintained exercise 150 minutes per week had a smaller decline in quality of life and mobility over two years compared to people who did not exercise or exercised ... Read more

Related support groups: Parkinson's Disease, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

New Parkinson's Drug Xadago Approved

Posted 22 Mar 2017 by Drugs.com

WEDNESDAY, March 22, 2017 – Xadago (safinamide) tablets have been approved by the U.S. Food and Drug Administration as an add-on drug to treat Parkinson's patients who take levodopa or carbidopa but have instances of increased symptoms anyway, a condition doctors call "off" episodes. An "off" episode, when Parkinson's medication doesn't seem to work well, may include symptoms such as tremor and difficulty walking, the agency said in a news release. Some 50,000 Americans are diagnosed each year with Parkinson's, and about 1 million Americans have the neurological condition, the FDA said, citing the U.S. National Institutes of Health. Typically diagnosed in people 60 and older, it occurs when brain cells that produce the chemical dopamine become impaired or die. The absence of enough dopamine leads to lack of smooth, purposeful movement during activities such as walking, eating, writing ... Read more

Related support groups: Parkinson's Disease, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

FDA OKs Parkinson's Add-On Drug

Posted 22 Mar 2017 by Drugs.com

WEDNESDAY, March 22, 2017 – The U.S. Food and Drug Administration has approved a new drug for Parkinson's disease. Xadago (safinamide) pills were given the green light as an add-on treatment for people taking levodopa/carbidopa and experiencing "off" episodes. These are periods when medication effectiveness wanes, leading to a rise in symptoms such as tremor and difficulty walking. "Parkinson's is a relentless disease without a cure," Dr. Eric Bastings said in an FDA news release. "We are committed to helping make additional treatments for Parkinson's disease available to patients," added Bastings, deputy director of neurology products in the FDA's Center for Drug Evaluation and Research. The FDA's approval of the drug is based on two clinical trials. The studies included a total of nearly 1,200 patients who were taking levodopa and experiencing "off" time. Those who added Xadago to ... Read more

Related support groups: Flexeril, Cyclobenzaprine, Parkinson's Disease, Dextromethorphan, Dry Cough, Mucinex DM, Sinemet, DayQuil, Alka-Seltzer, Daytime, Levodopa, Delsym, St. John's Wort, Carbidopa, Bromfed DM, C-Phen DM, Tylenol Cold, Promethazine DM, Tussin DM, Carbidopa/Levodopa

New Parkinson's Drug May Combat Movement Difficulties

Posted 4 Jan 2017 by Drugs.com

TUESDAY, Jan. 3, 2017 – New research suggests that people with Parkinson's disease may achieve better and more reliable motor control by taking an experimental drug called opicapone alongside the standard medication levodopa. A study of several hundred Parkinson's patients found that the drug – opicapone – boosts levodopa's ability to control the motor difficulties associated with Parkinson's, said study co-author Dr. Patricio Soares-da-Silva. These motor problems include tremors, stiffness, and slowed movement. Opicapone (Ongentys) appears to be an improvement over current treatment options, said Soares-da-Silva. He is director of research and development for the drug's maker, Bial-Portela & Ca. SA, in Portugal. There's no known cure for Parkinson's, a progressive neuro-degenerative disease. Nor is there any treatment that effectively slows or stops disease progression, according to ... Read more

Related support groups: Parkinson's Disease, Sinemet, Levodopa, Carbidopa/Levodopa, Stalevo, Rytary, Sinemet CR, Parkinsonian Tremor, Stalevo 100, Parkinsonism, Parcopa, Stalevo 200, Carbidopa/Entacapone/Levodopa, Stalevo 75, Stalevo 150, Dopar, Stalevo 50, Stalevo 125, Parkinson's Disease Psychosis, Atamet

Exercise May Be Real Medicine for Parkinson's Disease

Posted 22 Dec 2016 by Drugs.com

THURSDAY, Dec. 22, 2016 – Almost any exercise is good medicine for someone with Parkinson's disease, a new study confirms. Although physical activity may seem impossible for some Parkinson's patients, the new research review reaffirms what many specialists already believe: that exercise can have a long-term impact, improving gait and reducing risk of falls, in particular. "I pretty much never see a Parkinson's disease patient without recommending exercise," said Dr. Michael Okun, medical director of the Parkinson's Foundation. He is also chairman of neurology at the University of Florida. Parkinson's disease causes the brain to produce less dopamine, which leads to a loss of movement control. Physical symptoms include shaking, slowness and stiffness, but vary widely between individuals. The review measured the combined outcomes of more than 100 studies conducted over the past 30 years ... Read more

Related support groups: Benadryl, Parkinson's Disease, Diphenhydramine, Mirapex, Requip, Ropinirole, Sinemet, Pramipexole, Azilect, Levodopa, Carbidopa, Cabergoline, Cogentin, Emsam, Bromocriptine, Selegiline, Benztropine, Neupro, Benadryl Allergy, Amantadine

New Parkinson's Gene Identified

Posted 29 Nov 2016 by Drugs.com

TUESDAY, Nov. 29, 2016 – Researchers say they've identified a gene mutation that could be associated with early onset Parkinson's disease in white people. The mutation occurs in a gene that produces dopamine in the brain, and its impact is particularly strong in people younger than 50, according to the Iowa State University researchers. Rigidity and loss of muscle function in Parkinson's patients is linked with reduced levels of dopamine in the part of the brain that controls movement, the researchers said. Parkinson's is a progressive movement disorder that causes tremors and muscle rigidity. The researchers compared 289 people recently diagnosed with Parkinson's, but not on medication, and 233 healthy people. Overall, whites with one mutated version of the guanosine triphosphate cyclohydrolase-1 (GCH1) gene had a 23 percent increased risk of Parkinson's and developed disease symptoms ... Read more

Related support groups: Parkinson's Disease, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

Inhaled Version of Parkinson's Drug May Help Keep Symptoms at Bay

Posted 12 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 12, 2016 – An inhaled version of the Parkinson's drug levodopa can help when patients experience symptoms between doses of the pill form of the medication, a new, small study finds. Levodopa can control the tremors, rigidity and difficulty maintaining balance and coordination associated with Parkinson's disease. However, within two years, as many as half of all patients have rapid and unexpected loss of motor control during "off" periods, when the drug wears off between doses, the researchers explained. "Off periods are considered one of the greatest unmet medical needs in the treatment of Parkinson's, and typically increase in frequency during the course of the disease," said lead researcher Michael Lipp. He is vice president of pharmaceutical development and technical operations at Acorda Therapeutics, the drug's maker and funder of the study. Inhaled levodopa could ... Read more

Related support groups: Parkinson's Disease, Sinemet, Levodopa, Carbidopa/Levodopa, Stalevo, Rytary, Sinemet CR, Parkinsonian Tremor, Stalevo 100, Parkinsonism, Parcopa, Stalevo 200, Carbidopa/Entacapone/Levodopa, Stalevo 75, Stalevo 150, Dopar, Stalevo 50, Stalevo 125, Parkinson's Disease Psychosis, Atamet

Cellular Defect May Be Linked to Parkinson's: Study

Posted 8 Sep 2016 by Drugs.com

THURSDAY, Sept. 8, 2016 – Researchers say they've discovered a cellular defect that may be common to all forms of Parkinson's disease. The defect plays a major role in the die-off of a group of nerve cells whose loss is a hallmark of Parkinson's, according to the Stanford University team. The researchers conducted a series of experiments with cells from Parkinson's patients and healthy people. "We've found a molecular biomarker that characterizes not just familial cases of Parkinson's, in which a predisposition for the disease is clearly inherited, but also the condition's far more prevalent sporadic forms, for which the genetic contribution is either nonexistent or not yet discovered," said senior author Dr. Xinnan Wang, an assistant professor of neurosurgery. This defect prevents cells from quickly eliminating their internal power sources (mitochondria) when they wear out. So instead ... Read more

Related support groups: Parkinson's Disease, Diagnosis and Investigation, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

Experimental Test Detects Parkinson's Disease Earlier

Posted 29 Aug 2016 by Drugs.com

MONDAY, Aug. 29, 2016 – Scientists appear to have moved a step closer to developing a test that can detect Parkinson's disease in the early stages. The researchers developed a technique to identify a Parkinson's-associated molecule in spinal fluid samples from patients. In experiments, the technique accurately identified 19 of 20 samples from Parkinson's patients, plus three samples from people at risk for the disease, the study authors said. The technique detects a protein molecule called alpha-synuclein, which forms sticky clumps – called Lewy bodies – inside the brain cells of people with Parkinson's and some types of dementia, according to the researchers from the University of Edinburgh in Scotland. The scientists also tested the new technique on 15 healthy people to see if there were any false-positives. There were none. The new test didn't detect disease in any of the healthy ... Read more

Related support groups: Parkinson's Disease, Diagnosis and Investigation, Parkinsonian Tremor, Parkinsonism, Parkinson's Disease Psychosis

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