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Palbociclib News

New Drug May Brighten Outlook for Advanced Breast Cancer

Posted 16 days ago by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A recently approved drug can help slow the progression of advanced breast cancer, a new clinical trial confirms. The drug, called palbociclib (Ibrance), was approved in the United States last year for treating advanced cases of ER-positive breast cancer. That means the cancer uses the hormone estrogen to help fuel its growth. The approval was based on an earlier-stage study where the drug, used along with a standard drug called letrozole (Femara), helped keep women's cancer at bay. Palbociclib doubled the time patients remained progression-free compared to letrozole alone. The new findings, published in the Nov. 17 New England Journal of Medicine, confirm the earlier results in a larger group of women. "We found that the degree of clinical benefit was, again, remarkable," said lead researcher Dr. Richard Finn, an assistant professor of medicine at the ... Read more

Related support groups: Breast Cancer, Femara, Breast Cancer, Metastatic, Letrozole, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Ibrance, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Palbociclib

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Isotretinoin, Rituxan, Claravis

Pfizer Receives Expanded FDA Approval For Ibrance (palbociclib) In HR+, HER2- Metastatic Breast Cancer

Posted 23 Feb 2016 by Drugs.com

Friday, February 19, 2016 – Pfizer Inc. (NYSE:PFE) today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of Ibrance (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy. Now Ibrance also is approved for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer in combination with fulvestrant in women with disease progression following endocrine therapy.1 Pfizer’s supplemental New Drug Application (sNDA) for Ibrance was reviewed and approved under the FDA’s Breakthrough Therapy designation and Priority Review programs based on results from the Phase 3 PALOMA-3 trial in pre-, peri- and post-menopausal women with HR+, HER2- metastatic breast cancer whose disease progressed on or after prior endocrine therapy in the adjuvant or ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Ibrance, Palbociclib

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Femara, Lupron Depot, Gleevec, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Isotretinoin

New Drug Keeps Common Breast Cancer Under Control Longer: Study

Posted 30 May 2015 by Drugs.com

SATURDAY, May 30, 2015 – Adding a new drug called Ibrance (palbociclib) to standard hormone therapy helped keep a common type of breast cancer under control measurably longer than the hormone therapy alone, a new study shows. "Palbociclib stops cancer cells from growing," said study author Dr. Nicholas Turner, team leader at the Institute of Cancer Research in London, England. Adding the drug was so effective that the trial was stopped early so that those who were in the "control" group (taking an inactive placebo) could also be offered the drug. The findings are to be published online in the New England Journal of Medicine, to coincide with a planned presentation Saturday at the American Society of Clinical Oncology annual meeting in Chicago. Pfizer, the drug's maker, helped fund the study. Turner's team randomly assigned 521 women to get either Ibrance plus the standard hormone ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Ibrance, Breast Cancer - Palliative, Palbociclib

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Breast Cancer, Metastatic, Breast Cancer

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Ibrance

Palbociclib Patient Information at Drugs.com