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Osteomalacia News

In Mice, a Way for Stem Cells to Build Bone

Posted 31 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 31, 2016 – Researchers say they've found an easy way to spur stem cells to build bone in mice – a discovery that could lead to new treatments for bone disease. The team of scientists from the University of California, San Diego used a naturally occurring molecule called adenosine to prompt human stem cells to regenerate bone tissue. The new tissue helped repair cranial bone defects in the mice. Stem cells can become any type of cell in the body. But directing these cells to become muscle, bone or skin – a process known as differentiation – requires lengthy steps, according to the researchers. Stem-cell-derived tissues can also develop a type of tumor called teratomas – when cells differentiate the wrong way. The research team found that adding adenosine to the stem cell process helped build bone tissue in mice without any teratoma formation. The study was published ... Read more

Related support groups: Osteoporosis, Fracture, bone, Osteopenia, Bone Infection, Osteomyelitis, Diagnosis and Investigation, Osteomalacia

Injected Drug May Help Fight Osteoporosis in Women

Posted 16 Aug 2016 by Drugs.com

TUESDAY, Aug. 16, 2016 – An experimental drug appears to reduce the risk of bone fractures in postmenopausal women with osteoporosis better than a placebo and the currently available drug, a new study finds. In this phase 3 trial funded by the drug's maker, Radius Health, fewer women on the injectable drug abaloparatide had spine fractures (0.58 percent) than women receiving a placebo (4.22 percent) and slightly fewer than those taking a similar injectable drug, teriparatide (Forteo) (0.84 percent). "If this gets approved, and there is no reason to think it won't, this will be the second drug available for the treatment of high-risk osteoporosis," said lead researcher Dr. Paul Miller of the Colorado Center for Bone Research. Forteo has been in use for the past 16 years, he said. Abaloparatide works differently from Forteo and improves bone density more than Forteo, Miller said. Women ... Read more

Related support groups: Osteoporosis, Forteo, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Compression Fracture of Vertebral Column, Teriparatide, Osteomalacia, Prevention of Fractures

Health Tip: Help Prevent Falls

Posted 19 Jul 2016 by Drugs.com

-- Falling and potentially hurting yourself isn't a foregone part of getting older. To help prevent falls, the American Academy of Family Physicians suggests: Keep your home well lit, and install night lights throughout. Keep rugs securely fastened, or use a backing that prevents skidding. Make sure shoes have sturdy, nonskid soles. Don't leave electrical cords in areas where you walk. Install hand rails in the bathroom at the toilet and in the shower. Make sure stairways have railings on both sides. Read more

Related support groups: Osteoporosis, Fracture, bone, Osteomalacia, Prevention of Falls, Prevention of Fractures

Health Tip: Osteoporosis Shouldn't Be Ignored

Posted 17 Jun 2016 by Drugs.com

-- Osteoporosis occurs when the bones lose density and break more easily. Though it's a common problem, osteoporosis shouldn't be ignored. The National Osteoporosis Foundation says possible complications include: Broken bones. Chronic pain. Losing height. A hunched or stooped posture. Reduced mobility, which can result in feeling depressed or lonely. The potential need for nursing home care, such as for a broken hip. Read more

Related support groups: Osteoporosis, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Caltrate 600 with D, Compression Fracture of Vertebral Column, Os-Cal 500 with D, Calcium/Vitamin D, Citracal + D, Oysco 500 with D, Osteomalacia, Citracal Petites, Calcet, Calcium 600 D, Calcarb with D, Citracal Creamy Bites, Oyster Shell Calcium, Os-Cal with D, Prevention of Fractures, Dical Captabs

Serious Illness Affects Bone Health

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – A critical illness can lead to bone loss, a new study finds. The research included 66 seniors who spent at least 24 hours on a breathing machine in an intensive care unit (ICU). One year after their ICU stay, the patients had 1.6 percent less bone density in their lower spines and 1.2 percent less bone density in their thigh bones than would be expected. This bone loss may increase their risk of fractures, according to study author Neil Orford, ICU director at University Hospital Geelong in Australia, and colleagues. The researchers said critical illness may accelerate bone resorption. This is a process that occurs when bone is broken down, and calcium and other minerals are released into the bloodstream. A year after an ICU stay, the patients' resorption had returned to normal, but they were left with lower bone density, the study showed. The impact of this ... Read more

Related support groups: Infections, Bacterial Infection, Osteoporosis, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Viral Infection, ICU Agitation, Osteomalacia, Prevention of Fractures

Vitamin D Supplements Won't Strengthen Older Women's Bones: Study

Posted 3 Aug 2015 by Drugs.com

MONDAY, Aug. 3, 2015 – High doses of vitamin D do not appear to protect postmenopausal women from the dangers of osteoporosis, new research indicates. "While high-dose vitamin D did indeed increase calcium absorption, the increase was only 1 percent and [it] did not translate into gains in spine, hip or total body bone mineral density," said study author Dr. Karen Hansen. In fact, Hansen, an associate professor of medicine at the University of Wisconsin School of Medicine and Public Health in Madison, noted that she and her colleagues "did not find any benefit of vitamin D, in either high or low dose, on muscle mass, two tests of muscle fitness or fall [risk]." The team reported the results online Aug. 3 in the journal JAMA Internal Medicine. Postmenopausal women face a greater than average risk for developing osteoporosis, according to the U.S. National Institute of Arthritis and ... Read more

Related support groups: Hot Flashes, Menopausal Disorders, Osteoporosis, Postmenopausal Symptoms, Fracture, bone, Atrophic Vaginitis, Prevention of Osteoporosis, Osteopenia, Perimenopausal Symptoms, Caltrate 600 with D, Dyspareunia, Atrophic Urethritis, Compression Fracture of Vertebral Column, Os-Cal 500 with D, Calcium/Vitamin D, Citracal + D, Vaginal Dryness, Oysco 500 with D, Osteomalacia, Citracal Petites

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Vitamin D, ergocalciferol, Drisdol, calcium lactate, Posture, calcium phosphate, tribasic, calcium glubionate, Calciferol, Calcidol, Calcionate, Neo-Calglucon, Ridactate, Calciquid