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Knee Arthritis Drugs Beat Placebos, but Study Finds No Clear Winner

Posted 6 Jan 2015 by Drugs.com

TUESDAY, Jan. 6, 2015 – Pain-relieving treatments for knee arthritis all work better than doing nothing – but it's hard to point to a clear winner, a new research review concluded. Using data from almost 140 studies, researchers found all of the widely used arthritis treatments – from over-the-counter painkillers to pain-relieving injections – brought more relief to aching knees over three months than did placebo pills. But there were some surprises in the study, according to lead researcher Dr. Raveendhara Bannuru, of Tufts Medical Center in Boston. Overall, the biggest benefit came from injections of hyaluronic acid (HA) – a treatment some professional medical groups consider only marginally effective. Hyaluronic acid is a lubricating substance found naturally in the joints. Over the years, studies have been mixed as to whether injections of synthetic HA help arthritic joints, ... Read more

Related support groups: Osteoarthritis, Tylenol, Ibuprofen, Naproxen, Meloxicam, Acetaminophen, Diclofenac, Advil, Voltaren, Aleve, Mobic, Cortisone, Paracetamol, Motrin, Indomethacin, Toradol, Etodolac, Nabumetone, Flector, Panadol

Knee Injections for Arthritis? Save Your Money, Study Says

Posted 11 Jun 2012 by Drugs.com

MONDAY, June 11 – It's not good news for baby boomers with arthritic knees: Injections of hyaluronic acid have little effect on pain and no effect on function, according to a new analysis. Worse, the injections may cause serious harm, Swiss researchers found. Hyaluronic acid – a lubricant in joint fluid that acts as a shock absorber – declines with the wear-and-tear type of arthritis known as osteoarthritis. When nonsteroidal anti-inflammatory drugs don't provide relief, doctors sometimes prescribe injections of hyaluronic acid, also called viscosupplementation. "Unfortunately, there is no evidence to suggest that viscosupplementation results in any relevant reduction in symptoms in patients with knee osteoarthritis," said study co-author Dr. Peter Juni, professor of clinical epidemiology at the University of Bern in Switzerland. Moreover, his research suggested the injections could ... Read more

Related support groups: Osteoarthritis, Orthovisc, Hyaluronan

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