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'Managing' Elderly Patients Without Powerful Antipsychotics

Posted 26 Jul 2016 by Drugs.com

MONDAY, July 25, 2016 – About 25 percent of dementia patients in U.S. nursing homes are still quieted with risky antipsychotic medications. Now, a small study suggests that managing these difficult patients, instead of medicating them, could obtain better results. "Drugs have a place, but should not be first-line treatments. They don't work well, and there are side effects," said study author Dr. Henry Brodaty, a professor of aging and mental health at the University of New South Wales in Sydney, Australia. Antipsychotic drugs such as Risperdal (risperidone), Abilify (aripiprazole) and Seroquel (quetiapine) are approved to treat serious psychiatric conditions such as bipolar disorder and schizophrenia. But in seniors, they're often used to calm aggressive or violent behavior linked to dementia. "They're basically a sedative," said Dean Hartley, director of science initiatives with the ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Schizophrenia, Mania, Latuda, Dementia, Geodon, Zyprexa, Risperdal, Risperidone, Schizoaffective Disorder, Saphris, Quetiapine, Seroquel XR, Alzheimer's Disease, Olanzapine, Invega, Aripiprazole, Rexulti

Antipsychotics Don't Ease Delirium in Hospitalized Patients

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – Antipsychotic medications, such as haloperidol (Haldol) or clozapine (Clozaril), aren't appropriate for preventing or routinely treating delirium in hospitalized patients, a new study suggests. The researchers reviewed past studies and found that antipsychotic drugs given before surgery didn't prevent delirium. These drugs also didn't make any difference in the course of delirium in medical or surgical patients, the study authors said. "The American Geriatrics Society guidelines suggest avoiding using these medications as a part of routine care of a patient with delirium," said lead researcher Dr. Karin Neufeld, clinical director of psychiatry at Johns Hopkins Bayview Medical Center in Baltimore. Delirium causes confused thinking and diminished awareness of the environment, such as time and place. Delirium is often caused by physical or mental illness, such as ... Read more

Related support groups: Seroquel, Abilify, Lithium, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Seroquel XR, Olanzapine, Psychiatric Disorders, Invega, Haldol, Haloperidol, Aripiprazole, Rexulti, Clozapine, Compazine

Antipsychotic Drugs Tied to Risk of Early Death in Parkinson's Patients

Posted 22 Mar 2016 by Drugs.com

TUESDAY, March 22, 2016 – New research suggests that Parkinson's patients who are given antipsychotics to treat dementia and psychosis may be more likely to die early. However, the medications provide important benefits and the study authors aren't suggesting that these patients stop taking them. And it's still not clear exactly why there seems to be an increased risk of early death. "This [study] does not necessarily answer whether the drugs themselves lead to more deaths, or if it's instead the reasons they were prescribed," said Dr. Mark Baron, interim director of Virginia Commonwealth University's Parkinson's Disease and Movement Disorders Center. He wrote a commentary accompanying the new study. Antipsychotic drugs, despite their name, are used to treat a variety of mental conditions other than psychosis, including anxiety and dementia. As many as 60 percent of long-term ... Read more

Related support groups: Seroquel, Zyprexa, Risperdal, Risperidone, Parkinson's Disease, Quetiapine, Seroquel XR, Psychosis, Agitation, Olanzapine, Psychiatric Disorders, Haldol, Agitated State, Haloperidol, Symbyax, Thorazine, Chlorpromazine, Zyprexa Zydis, Risperdal Consta, Parkinsonian Tremor

Schizophrenia Tied to Much Higher Risk of Suicide Attempts

Posted 19 Feb 2016 by Drugs.com

THURSDAY, Feb. 18, 2016 – Schizophrenia patients are at significantly increased risk of attempting suicide, a new study finds. Researchers analyzed data from more than 21,700 Canadians, including 101 who had been diagnosed with schizophrenia. About 39 percent of people (two in five) with schizophrenia had attempted suicide, compared with about 3 percent of people without the mental health disorder. "Even after taking into account most of the known risk factors for suicide attempts, those with schizophrenia had six times the odds of having attempted suicide in comparison to those without schizophrenia," study author Esme Fuller-Thomson said in a University of Toronto news release. Fuller-Thomson is a professor of social work at the university. When researchers focused only on the 101 individuals with schizophrenia, they found that "women and those with a history of drug or alcohol abuse ... Read more

Related support groups: Depression, Wellbutrin, Seroquel, Major Depressive Disorder, Abilify, Lithium, Bupropion, Amitriptyline, Viibryd, Schizophrenia, Mirtazapine, Wellbutrin XL, Latuda, Remeron, Nortriptyline, Geodon, Zyprexa, Risperdal, Risperidone, Elavil

Many Seniors Given Antipsychotic Meds, Despite Potential Problems

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – Antipsychotic drug use in American seniors increases with age, a new study cautions. The researchers found that the percentage of people aged 80 to 84 who received a prescription for an antipsychotic drug was twice that of people aged 65 to 69. This increase is occurring despite the known risks of serious side effects such as stroke, kidney damage, and death, they added. "The results of the study suggest a need to focus on new ways to treat the underlying causes of agitation and confusion in the elderly," study author Dr. Mark Olfson, from the College of Physicians and Surgeons and Columbia University in New York City, said in a news release from the U.S. National Institute of Mental Health (NIMH). "The public health community needs to give greater attention to targeted environmental and behavioral treatments rather than medications," he added. The ... Read more

Related support groups: Seroquel, Abilify, Lithium, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Seroquel XR, Olanzapine, Invega, Haldol, Haloperidol, Aripiprazole, Rexulti, Clozapine, Compazine, Prochlorperazine

Brain Inflammation May Be Linked to Schizophrenia

Posted 16 Oct 2015 by Drugs.com

FRIDAY, Oct. 15, 2015 – Researchers say they've found a link between brain inflammation and schizophrenia. British investigators used PET scans to assess immune cell activity in the brains of 56 people. Some had schizophrenia, some were at risk for the mental disorder, and others had no symptoms or risk of the disease. The results showed that immune cells are more active in the brains of people with schizophrenia and those at risk for the disease. "Our findings are particularly exciting because it was previously unknown whether these cells become active before or after onset of the disease," lead author Peter Bloomfield, of the Medical Research Council's Clinical Sciences Center at Imperial College London, said in a college news release. "Now we have shown this early involvement, mechanisms of the disease and new medications can hopefully be uncovered," he added. The findings could ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Schizoaffective Disorder, Saphris, Quetiapine, Oppositional Defiant Disorder, Seroquel XR, Psychosis, Agitation, Olanzapine, Invega, Haldol, Agitated State

ERs Often 'Safety Net' Care for People With Schizophrenia: CDC

Posted 23 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 23, 2015 – A new report finds that, too often, under-medicated Americans suffering from schizophrenia end up seeking care in the nation's hospital emergency rooms. The report, issued Wednesday by the U.S. Centers for Disease Control and Prevention, found that between 2009 and 2011, over 382,000 visits to ERs were recorded for people aged 18 to 64 with schizophrenia. Many of these cases involved people on Medicaid who were either homeless or living in places such as nursing homes or group homes, the researchers said. Emergency departments "may serve as a safety net for schizophrenic patients not otherwise receiving care," said Dr. Michael Albert and Linda McCaig, both of whom work at the CDC's National Center for Health Statistics (NCHS). Mental health expert Dr. Michael Birnbaum said the new findings were "not surprising." "Unfortunately many people with mental illness ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Schizoaffective Disorder, Saphris, Quetiapine, Seroquel XR, Psychosis, Olanzapine, Invega, Haldol, Haloperidol, Aripiprazole, Rexulti

Are Too Many Young Americans Getting Antipsychotics for ADHD?

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – A growing number of teens and young adults are being prescribed powerful antipsychotics, even though the medications aren't approved to treat two disorders – ADHD and depression – they are commonly used for, a new study shows. Researchers found that antipsychotic use rose among children aged 13 and older – from 1.1 percent in 2006 to nearly 1.2 percent in 2010. And among young adults – people aged 19 to 24 – antipsychotic use increased from 0.69 percent in 2006 to 0.84 percent in 2010. Of concern to some experts are the conditions for which many of these antipsychotic prescriptions are being written, namely attention-deficit hyperactivity disorder (ADHD) and depression. Currently, the U.S. Food and Drug Administration approves this class of drugs for psychiatric conditions such as psychosis, bipolar disorder, schizophrenia or impulsive aggression tied to ... Read more

Related support groups: Depression, Seroquel, Major Depressive Disorder, Abilify, Attention-Deficit Hyperactivity Disorder (ADHD), Lithium, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Oppositional Defiant Disorder, Seroquel XR, Olanzapine, Invega, Haldol, Dysthymia, Haloperidol

Existing Drugs May Work Against MERS, Studies Suggest

Posted 20 May 2014 by Drugs.com

MONDAY, May 19, 2014 – As media reports warn of the first cases of the potentially deadly MERS virus in the United States, three new studies suggest that certain existing drugs might help fight the illness. So far, three U.S. patients have been identified as having been infected with Middle East Respiratory Syndrome (MERS) virus, according to the U.S. Centers for Disease Control and Prevention. One, a man from Illinois, has shown no symptoms but tested positive for infection. The other two – one man in Florida, another in Indiana – had recently returned from Saudi Arabia and got sick but have since recovered. The MERS virus first surfaced in 2012 in the Middle East, where most of the cases have occurred. Since that time, there have been 536 laboratory-confirmed cases and 145 deaths, according to the World Health Organization. Symptoms typically include shortness of breath, coughing ... Read more

Related support groups: Thorazine, Chlorpromazine, Chloroquine, Aralen Hydrochloride, Ormazine, Middle East Respiratory Syndrome, Aralen, Aralen Phosphate

FDA Medwatch Alert: Olympia Pharmacy Sterile Compounded Products: Recall - Concerns About Sterility Assurance

Posted 5 Jun 2013 by Drugs.com

  [Posted 05/30/2013] ISSUE: Lowlite Investments d/b/a Olympia Pharmacy ("Lowlite") notified the public of a voluntary multi-state recall of all sterile drug products compounded by the pharmacy that have not reached the expiration date listed on the product. The recall is being initiated due to concerns associated with prior quality control procedures that impacted sterility assurance. In the event a sterile product is compromised patients are at risk for serious and possible life threatening infections. The recall includes all sterile products that Olympia Pharmacy supplied to patients and offices of licensed medical professionals with a use by date of 09/25/2013 or earlier. Olympia Pharmacy will be notifying customers by phone, fax, or mail to return the products to the pharmacy. BACKGROUND: To date, Lowlite has received no reports of injury or illness associated with the use of the a ... Read more

Related support groups: Provera, Depo-Provera, Subutex, Estradiol, Meloxicam, Testosterone, Methylprednisolone, Butrans, AndroGel, Mobic, Medroxyprogesterone, Buprenorphine, Estrace, Medrol, Testim, Reglan, Vivelle, Axiron, Climara, Oxytocin

Psychiatric Drugs More Often Prescribed in the South

Posted 1 Feb 2013 by Drugs.com

FRIDAY, Feb. 1 – Use of psychiatric medications is most prevalent in the southern United States and least prevalent in the West, according to a new U.S. study. Although people living in the West are the least likely to use antipsychotics, antidepressants and stimulants, the Yale researchers found that the drugs' use is 40 percent higher in a large section of the South than in other parts of the country. The study authors attributed this discrepancy to variations in local access to health care and marketing efforts within the pharmaceutical industry. "The geographic patterns we identify are striking and map onto the patterns found for a host of other medical conditions and treatments, from cognitive decline to bypass surgery," Marissa King, assistant professor of organizational behavior at the Yale School of Management, said in a school news release. "Our work suggests that access to ... Read more

Related support groups: Depression, Bipolar Disorder, Adderall, Lexapro, Zoloft, Wellbutrin, Cymbalta, Effexor, Prozac, Paxil, Seroquel, Celexa, Phentermine, Citalopram, Vyvanse, Trazodone, Abilify, Sertraline, Pristiq, Lithium

Older Antipsychotics May Work as Well as Newer Ones: Review

Posted 14 Aug 2012 by Drugs.com

TUESDAY, Aug. 14 – Newer, more expensive schizophrenia medications are not noticeably better than their older, cheaper counterparts, a new review suggests. Currently, 75 percent of U.S. adults who are prescribed antipsychotic medications take these second-generation drugs, which were developed largely due to concerns about side effects with their predecessors, experts noted. First-generation antipsychotics are also called typical antipsychotics. This class of drugs includes chlorpromazine (Thorazine), haloperidol (Haldol), perphenazine (Etrafon, Trilafon) and fluphenazine (Prolixin). Second-generation drugs, known as atypical, antipsychotics include risperidone (Risperdal), aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine Fumarate (Seroquel) and ziprasidone (Geodon). There is a major cost difference between the two classes of drugs: For example, a month's supply of olanzapine ... Read more

Related support groups: Seroquel, Abilify, Latuda, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Seroquel XR, Olanzapine, Invega, Haldol, Haloperidol, Aripiprazole, Clozapine, Compazine, Prochlorperazine, Thorazine, Perphenazine

Antipsychotic Drugs Raise Heart Risks, Experts Warn

Posted 18 Feb 2011 by Drugs.com

FRIDAY, Feb. 18 – Doctors must not forget about the physical health of people with serious mental health disorders who take antipsychotic drugs, experts warn. The authors of an editorial in the Feb. 19 issue of The Lancet noted that patients with severe mental illness live an average of 16 years less than people in the general population. Heart disease, not suicide, is the major cause of death in these patients and antipsychotic drugs are a factor. A study published recently in the Archives of General Psychiatry found that patients who took an antipsychotic drug gained 11 to 13 pounds within six to eight weeks after they starting taking the drug. "The combination of antipsychotic side effects with poor diet, physical inactivity, high rates of smoking and other factors associated with psychotic illness, together with socioeconomic deprivation, has a devastating effect on cardiometabolic ... Read more

Related support groups: Seroquel, Abilify, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Seroquel XR, Olanzapine, Invega, Aripiprazole, Clozapine, Compazine, Prochlorperazine, Thorazine, Perphenazine, Clozaril, Chlorpromazine, Fanapt

Schizophrenia Drugs May Spur Subtle Brain Tissue Loss

Posted 10 Feb 2011 by Drugs.com

MONDAY, Feb. 7 – The use of antipsychotic drugs to treat schizophrenia is associated with the loss of a small but measurable amount of brain tissue, a new study finds. It included 211 schizophrenia patients who each underwent an average of three MRI brain scans over 7.2 years, for a total of 674 scans in the study group. The researchers then examined how four factors affected changes in brain volume over time: illness duration, illness severity, substance abuse and treatment with antipsychotic drugs. Longer duration of illness and antipsychotic treatment were both associated with loss of brain tissue. Higher doses of antipsychotics were associated with overall brain tissue loss, reduced gray matter and progressive declines in white matter. Illness severity and substance abuse had little or no association with brain tissue changes, according to the study, published in the February issue ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Geodon, Zyprexa, Risperdal, Risperidone, Saphris, Quetiapine, Seroquel XR, Olanzapine, Invega, Haldol, Haloperidol, Aripiprazole, Clozapine, Compazine, Prochlorperazine, Thorazine

FDA Medwatch Alert: Antipsychotics, Conventional and Atypical

Posted 16 Jun 2008 by Drugs.com

[Posted 06/16/2008] FDA notified healthcare professionals that both conventional and atypical antipsychotics are associated with an increased risk of mortality in elderly patients treated for dementia-related psychosis. In April 2005, FDA notified healthcare professionals that patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death. Since issuing that notification, FDA has reviewed additional information that indicates the risk is also associated with conventional antipsychotics. Antipsychotics are not indicated for the treatment of dementia-related psychosis. The prescribing information for all antipsychotic drugs will now include the same information about this risk in a BOXED WARNING and the WARNINGS section.[June 16, 2008 - Information for Healthcare Professionals - FDA] Read more

Related support groups: Seroquel, Abilify, Dementia, Geodon, Zyprexa, Risperdal, Invega, Haldol, Compazine, Symbyax, Trilafon, Navane, Stelazine, Mellaril, Orap, Loxitane, Moban, Clopine, Permitil, Ormazine

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