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These Medicines Often Send Americans to ERs

Posted 10 days ago by Drugs.com

TUESDAY, Nov. 22, 2016 – An estimated one in 250 Americans lands in the hospital emergency department each year because of a medication-related reaction or problem, a new federal study finds. Among adults 65 and older, the rate is about one in 100, the study authors said. Remarkably, the medicines causing the most trouble haven't changed in a decade, the researchers noted. Blood thinners, diabetes medicines and antibiotics top the list. These drugs accounted for 47 percent of emergency department visits for adverse drug events in 2013 and 2014, according to the analysis. Among older adults, blood thinners, diabetes medicines and opioid painkillers are implicated in nearly 60 percent of emergency department visits for adverse drug events. "The same drugs are causing the most problems," said study co-author Dr. Daniel Budnitz. The study doesn't tease out what went wrong. The reasons ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Diabetes, Type 2, Back Pain, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Opana, Warfarin, Coumadin, Subutex

Have Type 2 Diabetes? Try Walking After Eating

Posted 18 Oct 2016 by Drugs.com

TUESDAY, Oct. 18, 2016 – For people with type 2 diabetes, a short walk after eating may help lower blood sugar levels more than exercising at other times of the day, a new study shows. A measurement of blood sugar called postprandial glycemia, which has been linked with heart disease risk, averaged 12 percent lower when study participants took a walk after eating, compared with those who exercised at other times. The largest drop in postprandial glycemia, 22 percent, was achieved by walking after dinner, the study authors found. "If you have type 2 diabetes, there is a guideline to be active for at least 150 minutes a week," said study author Andrew Reynolds, a researcher at the University of Otago, in New Zealand. But, he added, "the benefits we observed due to physical activity after meals suggest that current guidelines should be amended to specify after-meal activity, particularly ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Glipizide, Insulin Resistance, Glyburide, Invokana, Actos, Glimepiride, Pre-Diabetes, Amaryl, Pioglitazone, Diabetes Mellitus, Avandia, GlipiZIDE XL, Glucotrol, Farxiga, Jardiance, Acarbose, Glucotrol XL, Ischemic Heart Disease

Intensive Type 2 Diabetes Treatment Can Extend Survival: Study

Posted 8 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Intensive management of type 2 diabetes can make a difference in how long and how well you live, even if you don't start until middle age, researchers report. People who were already at risk of type 2 diabetes complications were randomly selected to continue with their normal treatment or to be placed in an aggressive and multipronged treatment group. Two decades after the study began, the researchers found that people in the aggressive treatment group lived almost eight years longer. Not only that, they lived better – their risk of heart disease, kidney disease and blindness all dropped. The only complication that didn't seem to improve was nerve damage caused by diabetes. "Early, intensified intervention in type 2 diabetes patients with microalbuminuria with both target-driven pharmacological (medication) and behavioral actions increased life span. And, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Humalog, Janumet, Byetta, Glyburide, Saxenda, Bydureon, Lantus Solostar, Invokana, Levemir, Actos, Glimepiride

Intensive Blood Sugar Control May Be Too Much for Some With Type 2 Diabetes

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Intensive treatment of blood sugar levels in some people with type 2 diabetes may cause serious complications, new research suggests. "In this study, we found that, particularly among older patients and patients with serious chronic conditions, intensive treatment nearly doubled the risk of severe hypoglycemia requiring medical attention, including hospitalization," said lead author Dr. Rozalina McCoy. She is an endocrinologist at the Mayo Clinic in Rochester, Minn. Hypoglycemia (low blood sugar) is a serious potential complication of diabetes treatment. The researchers said it can worsen quality of life and has been linked with cardiovascular events, dementia and death. The researchers reviewed information from more than 31,500 American adults. All had stable and controlled type 2 diabetes. None was taking insulin. None had a prior history of severe ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Dementia, Glucophage, Novolog, Glipizide, Humalog, Hypoglycemia, Janumet, Glyburide, Lantus Solostar, Invokana, Levemir, Actos, Glimepiride, Amaryl, Novolin R, Mild Cognitive Impairment

Metformin Safer for Heart Than Other Common Type 2 Diabetes Drugs: Study

Posted 18 Apr 2016 by Drugs.com

MONDAY, April 18, 2016 – Metformin, the most frequently prescribed standalone drug for type 2 diabetes, is better for the heart than its closest competitors, a large analysis suggests. Metformin reduced the risk of dying from heart attack and stroke by about 30 percent to 40 percent compared with other commonly used drugs called sulfonylureas, such as glibenclamide, glimepiride, glipizide and tolbutamide, researchers report. "Pharmaceutical companies continue to make new drugs to reduce blood sugar and improve on safety concerns of the older drugs," said senior study author Dr. Shari Bolen. But, "while adults with diabetes often need more than one medication to control blood sugar, the newer medications do not appear to be safer than the older drugs," added Bolen. Metformin is still the safest and most effective type 2 diabetes medication, said Bolen. She is an assistant professor of ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glipizide, Janumet, Glimepiride, Amaryl, Prevention of Cardiovascular Disease, Glucophage XR, GlipiZIDE XL, Glucotrol, Cardiovascular Risk Reduction, ActoPlus Met, Glucotrol XL, Glumetza, Glyburide/Metformin, Janumet XR, Avandamet, Jentadueto, Glucovance

Cost of Insulin Rises Threefold in Just a Decade: Study

Posted 5 Apr 2016 by Drugs.com

TUESDAY, April 5, 2016 – Americans with diabetes who rely on insulin to keep their blood sugar levels in check are facing sticker shock: A new study finds the price of insulin has tripled in only 10 years. Moreover, since 2010, per-person spending on insulin in the United States was more than spending on all other diabetes drugs, the study found. "The cost of insulin has risen rapidly over the last few years," said study senior author Philip Clarke, a professor of health economics at the University of Melbourne in Australia. Clarke added there should be an assessment to see whether this price hike is justifiable in terms of improved clinical outcomes. One reason for the price climb, he said, is a switch from human insulins to analog insulins, which cost more but may offer additional benefits. Also, doctors are more apt to prescribe insulin for people with type 2 diabetes now, Clarke ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Diabetes, Type 1, Januvia, Glucophage, Novolog, Diabetic Neuropathy, Glipizide, Humalog, Janumet, Insulin Resistance, Diabetic Nerve Damage, Byetta, Glyburide, Saxenda, Bydureon, Lantus Solostar

Diabetes Meds Vary in Safety and Effectiveness, Study Shows

Posted 31 Mar 2016 by Drugs.com

THURSDAY, March 31, 2016 – A study of nearly a half-million people with type 2 diabetes shows there are pros and cons to nearly every form of drug therapy for the disease. In the British study, researchers looked at patient outcomes from a large U.K. database of almost 470,000 adults with type 2 diabetes, tracked between 2007 and 2015. Julia Hippisley-Cox and Carol Coupland, of the University of Nottingham, sought to parse out differences among a variety of diabetes drugs. They accounted for complicating patient factors such as age, sex, smoking and poverty, as well as how long a person had been diagnosed with type 2 diabetes. The researchers also focused on five major outcomes linked to diabetes: blindness, amputation, severe kidney failure, and high or low blood sugar. Reporting March 30 in BMJ, they found that when a class of drugs called glitazones (Actos, Avandia) was prescribed ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glipizide, Janumet, Insulin Resistance, Glyburide, Actos, Pre-Diabetes, Glimepiride, Amaryl, Diabetes Mellitus, Avandia, Glucophage XR, Prandin, GlipiZIDE XL, Glucotrol, ActoPlus Met, Glucotrol XL, Glumetza

Blood Thinner, Certain Diabetes Drugs Are a Bad Combo

Posted 8 Dec 2015 by Drugs.com

TUESDAY, Dec. 8, 2015 – Taking the blood thinner warfarin at the same time as certain diabetes drugs increases the risk of hospitalization, a new study warns. Researchers analyzed data from nearly 466,000 Medicare patients. They found that those who took warfarin along with the diabetes drugs glipizide or glimepiride – also known as sulfonylureas – had a 22 percent increased risk of making an emergency room visit or being hospitalized for low blood sugar (hypoglycemia). While doctors are warned about potential interaction between the drugs, there has been little actual data, said study author John Romely, an associate professor at the University of Southern California Center for Health Policy and Economics and School of Public Policy. "Until now, no one had really studied the interactions between them," he said in a university news release. The risk was especially high for men aged ... Read more

Related support groups: Diabetes, Type 2, Warfarin, Coumadin, Glipizide, Glyburide, Glimepiride, Amaryl, GlipiZIDE XL, Glucotrol, Glucotrol XL, DiaBeta, Jantoven, Glipizide/Metformin, Tolazamide, Chlorpropamide, Glimepiride/Pioglitazone, Glynase, Micronase, Glycron, Glynase PresTab

New Diabetes Cases Among Americans Drop for First Time in Decades: CDC

Posted 1 Dec 2015 by Drugs.com

TUESDAY, Dec. 1, 2015 – In a sign that Americans may finally be turning the corner in the fight against diabetes – and possibly obesity – federal health statistics released Tuesday show that the number of new cases of diabetes has dropped for the first time in decades. The decline wasn't sudden or dramatic. But, the number of new diabetes cases went from 1.7 million in 2009 to 1.4 million in 2014, according to the U.S. Centers for Disease Control and Prevention. "It seems pretty clear that incidence rates have now actually started to drop. Initially it was a little surprising because I had become so used to seeing increases everywhere we looked," CDC researcher Edward Gregg told The New York Times. The proportion of Americans with diabetes is still twice what it was in the early 1990s. And not every racial group has made strides against the blood sugar disease, which is often ... Read more

Related support groups: Diabetes, Type 2, Obesity, Metformin, Insulin, Weight Loss, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Humalog, Janumet, Byetta, Saxenda, Glyburide, Bydureon, Lantus Solostar, Invokana, Levemir

Too Many Seniors With Diabetes Are Overtreated, Study Suggests

Posted 29 Oct 2015 by Drugs.com

THURSDAY, Oct. 29, 2015 – When it comes to treating seniors with diabetes, new research suggests that doctors often don't cut back on medications, even when treatment goals are surpassed. The study found that when people had potentially dangerous low blood sugar levels, just 27 percent had their medicines decreased. And when blood pressure treatments lowered blood pressure levels too much, just 19 percent saw a reduction in their medications. "As people get older, the risks of overtreating become greater, and the benefits become shorter. We have to start emphasizing that more isn't always better," said study author Dr. Jeremy Sussman, an assistant professor of internal medicine at the University of Michigan in Ann Arbor and a primary care doctor at the Ann Arbor VA System. The findings were published online Oct. 26 in the journal JAMA Internal Medicine. Practice guidelines generally ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Humalog, Janumet, Byetta, Glyburide, Saxenda, Bydureon, Lantus Solostar, Invokana, Levemir, Actos, Glimepiride

Tight Control of Type 2 Diabetes May Help Prevent Dementia

Posted 15 Sep 2015 by Drugs.com

TUESDAY, Sept. 15, 2015 – Keeping blood sugar levels in check may have a protective effect against dementia in people who have type 2 diabetes, new Swedish research suggests. "The positive association between [average blood sugar levels] and risk of dementia in fairly young patients with type 2 diabetes indicates a potential for prevention of dementia with improved blood sugar control," study author Dr. Aidin Rawshani, from the National Diabetes Register and Institute of Medicine in Gothenburg, Sweden, and colleagues wrote. However, the study wasn't able to definitively prove a cause-and-effect relationship between blood sugar levels and dementia; it was only able to show an association between these factors. The study included almost 350,000 people with type 2 diabetes. They were all registered in the Swedish National Diabetes Registry between January 2004 and December 2012. They had ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Dementia, Glucophage, Alzheimer's Disease, Novolog, Glipizide, Humalog, Janumet, Glyburide, Lantus Solostar, Invokana, Levemir, Actos, Glimepiride, Amaryl, Novolin R, Mild Cognitive Impairment

Health Tip: Diabetes Can Take a Toll on Teeth and Mouth

Posted 10 Aug 2015 by Drugs.com

-- Diabetes, especially when uncontrolled, can cause damage to your mouth and teeth. The Mouthhealthy.org website says possible effects of diabetes on the teeth and mouth include: Dry mouth, due to decreased saliva production. Increased risk of cavities due to less saliva. Gingivitis, characterized by bleeding, inflamed gums. Difficulty tasting food. Slower healing of mouth wounds. Increased risk of infection. Among diabetic children. teeth emerging earlier than expected. Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Oral and Dental Conditions, Xerostomia, Lantus, Toothache, Diabetes, Type 1, Januvia, Glucophage, Novolog, Diabetic Neuropathy, Burning Mouth Syndrome, Glipizide, Humalog, Janumet, Insulin Resistance, Diabetic Nerve Damage, Aphthous Ulcer

People With Type 2 Diabetes Do Benefit From Blood Sugar Checks

Posted 5 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 5, 2015 – Personalized blood sugar self-monitoring benefits people with type 2 diabetes even if they're not taking insulin, a new small study shows. Some experts have questioned the value of self-monitoring in this group, and many insurers – including Medicare – limit the reimbursement of blood sugar (glucose) testing strips to one a day for people with type 2 diabetes. This study included 11 people with type 2 diabetes who worked with the researchers to create personalized, structured self-monitoring blood glucose schedules. In most cases, self-monitoring twice a day was the most helpful in providing meaningful information about blood sugar levels. However, there was room for individualization based on a patient's type of lifestyle and needs. For example, a patient might check their blood sugar twice a day three days a week instead of once a day seven days a week, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Humalog, Janumet, Byetta, Glyburide, Saxenda, Bydureon, Lantus Solostar, Invokana, Levemir, Actos, Glimepiride

Weight-Loss Surgery May Beat Diet, Exercise as Type 2 Diabetes Treatment

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – In a small study of obese patients, weight-loss surgery was better at keeping type 2 diabetes at bay than diet and exercise alone, researchers report. In fact, three years after weight-loss surgery, more than two-thirds of those who had a procedure called Roux-en-Y gastric bypass to shrink their stomach didn't need any diabetes medications. And one-third of the people who chose a procedure called adjustable gastric banding no longer needed diabetes medications three years after surgery, the study found. "Surgical treatments show promise for durable, longer-term, type 2 diabetes control in people with obesity," said lead researcher Dr. Anita Courcoulas, a professor of surgery at the University of Pittsburgh Medical Center. The report was published July 1 online in JAMA Surgery. The researchers recruited 61 obese patients with type 2 diabetes for the study. They ... Read more

Related support groups: Diabetes, Type 2, Obesity, Insulin, Weight Loss, Lantus, Novolog, Glipizide, Humalog, Glyburide, Lantus Solostar, Levemir, Actos, Glimepiride, Novolin R, Amaryl, Novolin N, Pioglitazone, Avandia, Humulin N, Lantus Solostar Pen

Exercise May Have Benefits Beyond Fitness in Type 2 Diabetes

Posted 17 Jun 2015 by Drugs.com

WEDNESDAY, June 17, 2015 – Exercise appears to benefit people with type 2 diabetes in a number of ways, a new study suggests. Researchers at the University of Texas Southwestern Medical Center at Dallas looked at health records from people with type 2 diabetes. They found that people who exercised had lower body fat, smaller waist size and better blood sugar control than people who were inactive. The positive effects of exercise were seen whether people did aerobic exercise, resistance training or a combination of the two. People also saw positive effects from exercise even if they didn't have any improvement in their heart/lung (cardiorespiratory) fitness, the investigators found. "What we observed is that exercise improves diabetes control regardless of improvement in exercise capacity," co-author Dr. Jarett Berry, associate professor of internal medicine and clinical sciences at UT ... Read more

Related support groups: Diabetes, Type 2, Obesity, High Cholesterol, Weight Loss, Glipizide, Glyburide, Actos, Glimepiride, Amaryl, Pioglitazone, Avandia, GlipiZIDE XL, Glucotrol, Glucotrol XL, DiaBeta, Rosiglitazone, Glynase, Micronase, Tolazamide, Chlorpropamide

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