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Could Common Heartburn Drugs Up Stroke Risk?

Posted 19 days ago by Drugs.com

TUESDAY, Nov. 15, 2016 – A popular category of heartburn medications – including Nexium, Prevacid, Prilosec and Protonix – may increase your risk of stroke, a new study suggests. Known as proton pump inhibitors (PPIs), these drugs increased people's overall stroke risk by 21 percent, said study lead author Dr. Thomas Sehested. However, the risk appears to be driven by people who take high doses, added Sehested, research director at the Danish Heart Foundation in Copenhagen. "People treated with a low dose of PPIs did not have a high risk of stroke," he said. "Those treated with the highest doses of PPIs had the highest risk of stroke." The extent of risk also depends on the specific PPI taken. At the highest dose, stroke risk ranged from 30 percent for lansoprazole (Prevacid) to 94 percent for pantoprazole (Protonix), the researchers said. Takeda Pharmaceutical, the maker of ... Read more

Related support groups: GERD, Heart Disease, Ischemic Stroke, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Zantac, Protonix, Alzheimer's Disease, Pantoprazole, Ranitidine, Dexilant, Lansoprazole, Prevacid, Transient Ischemic Attack, Pepcid, Barrett's Esophagus, Aciphex

Common Heartburn Drugs Linked to Kidney Disease in Study

Posted 15 Apr 2016 by Drugs.com

THURSDAY, April 14, 2016 – People who use certain drugs for chronic heartburn may be at increased risk of developing kidney disease, a new study suggests. The research is the latest to highlight potential risks from drugs called proton pump inhibitors (PPIs). PPIs include prescription and over-the-counter drugs, such as Prilosec, Prevacid and Nexium. But prolonged use of PPIs has been linked to certain nutrient deficiencies and bone-density loss. According to the U.S. Food and Drug Administration, bone fractures are considered a safety concern when people use PPIs for a year or more. More recently, research has hinted at additional hazards. Last year, for example, a study tied the medications to a slight increase in heart attack risk. However, neither that study nor this new one prove that PPIs are directly to blame for these problems. "I cannot say for certain that this is ... Read more

Related support groups: GERD, Omeprazole, Prilosec, Protonix, Renal Failure, Pantoprazole, Barrett's Esophagus, Chronic Kidney Disease, Zegerid, Prilosec OTC, Omeclamox-Pak, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide, Zegerid OTC, Protonix IV, Omeprazole/Sodium Bicarbonate, Renal and Genitourinary Disorders, Omesec, Amoxicillin/clarithromycin/omeprazole

Widely Used Heartburn Drugs Linked to Dementia Risk in Study

Posted 15 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more

Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Protonix, Alzheimer's Disease, Pantoprazole, Stomach Ulcer, Dexilant, Lansoprazole, Prevacid, Gastric Ulcer, Aciphex, Peptic Ulcer, Duodenitis/Gastritis, Prevpac, Mild Cognitive Impairment

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