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Common Heartburn Meds Show Ties to Kidney Trouble

Posted 18 days ago by Drugs.com

SATURDAY, Nov. 4, 2017 – If you're one of the millions of Americans who takes one of a class of anti-reflux meds such as Nexium, Prilosec and Prevacid, take heed: These drugs have been linked to higher odds of kidney trouble. The study couldn't prove cause-and-effect – it's possible that folks who need these heartburn medicines are simply more prone to kidney disease for other reasons. But the review of data did show a link. The medicines in question are called proton pump inhibitors (PPIs). They reduce stomach acid production and are among the most widely prescribed medications in the world. According to a team led by Dr. Charat Thongprayoon, of Bassett Medical Center in Cooperstown, N.Y., recent research has suggested an increased risk of kidney problems for people who take the drugs, but those findings were inconsistent. Probing deeper, the researchers reviewed data from five ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Indigestion, Renal Failure, Lansoprazole, Prevacid, Barrett's Esophagus, Chronic Kidney Disease, Duodenitis/Gastritis, Esomeprazole, Prevpac, Vimovo, Zegerid, Prilosec OTC, Amoxicillin/Clarithromycin/Lansoprazole, NSAID-Induced Ulcer Prophylaxis, Zegerid OTC, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide

Blood Thinners Can Come With Dangerous Side Effects

Posted 3 Oct 2017 by Drugs.com

TUESDAY, Oct. 3, 2017 – Blood-thinning drugs can save your life by preventing a heart attack or stroke caused by artery-blocking blood clots. But these are powerful drugs, and a pair of new studies detail side effects people need to understand before taking them. The effectiveness of a class of blood thinners called nonvitamin K oral anticoagulants (NOACs) can be significantly altered through interaction with other drugs, the first study reveals. In some cases, these drug interactions increase a person's risk of life-threatening bleeding in locations such as the brain and gastrointestinal tract. In other cases, the NOACs' effectiveness is reduced, robbing patients of some protection against stroke and heart attack. "NOACs alone do not pose a significant risk of bleeding, but the concurrent use of NOACs with certain drugs that share the same metabolic pathways may cause increased risk ... Read more

Related support groups: Warfarin, Coumadin, Xarelto, Lipitor, Atorvastatin, Pradaxa, Eliquis, Erythromycin, Clarithromycin, Digoxin, Biaxin, Rivaroxaban, Apixaban, Prevpac, MY-E, Caduet, A/T/S, Lanoxin, Amoxicillin/Clarithromycin/Lansoprazole, Arixtra

Decline in Kids' Ear Infections Linked to Pneumococcal Vaccine

Posted 7 Aug 2017 by Drugs.com

MONDAY, Aug. 7, 2017 – American kids' ear infections dropped threefold over 10 years, compared to the 1980s, largely due to pneumococcal vaccines that protect against one type of bacteria that causes them, a new study suggests. However, the study, which tracked more than 600 children from 2006 to 2016, also found a shift in the bacteria now triggering greater numbers of ear infections. The investigators also found that these germs are not killed by amoxicillin, the top-recommended antibiotic for the condition. "The magnitude of the drop in the occurrence of ear infections was more than I expected," said study author Dr. Michael Pichichero. He's director of the Rochester General Hospital Research Institute in Rochester, N.Y. "The second big finding is we've got this shift in the No. 1 bacteria. If something is not done, I would expect ear infections to come back in frequency," ... Read more

Related support groups: Amoxicillin, Augmentin, Otitis Media, Amoxicillin/Clavulanate, Amoxil, Prevnar 13, Prevpac, Amoxicillin/Clarithromycin/Lansoprazole, Amoclan, Amoxil Pediatric Drops, Pneumococcal 23-polyvalent Vaccine, Pneumovax 23, Augmentin XR, Pneumococcal Disease Prophylaxis, Augmentin ES-600, Biomox, Otitis Media with Perforation of Ear Drum, Chronic Otitis Media, Omeclamox-Pak, Moxatag

Popular Heartburn Meds Don't Raise Alzheimer's Risk: Study

Posted 28 Jun 2017 by Drugs.com

WEDNESDAY, June 28, 2017 – Drugs used to treat acid reflux and ulcers don't appear to boost the risk of dementia, as has been previously suspected, new research suggests. The study focused on widely used proton pump inhibitors (PPIs) drugs – medicines such as Prevacid, Prilosec and Nexium. Previous studies have suggested the drugs may increase the risk of dementia and Alzheimer's disease in people aged 75 and older. PPIs are used to treat digestive problems like reflux disease by reducing the body's production of acid. Researchers from Emory University in Atlanta analyzed a National Alzheimer's Coordinating Center database for the study. The data, compiled from 2005 to 2015, included close to 10,500 Americans, aged 50 or older, with normal brain function or mild thinking difficulties. Eight percent always used PPIs, and 18 percent sometimes did. Users were older than non-users. ... Read more

Related support groups: GERD, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Pantoprazole, Protonix, Alzheimer's Disease, Stomach Ulcer, Dexilant, Lansoprazole, Prevacid, Barrett's Esophagus, Gastric Ulcer, Duodenitis/Gastritis, Aciphex, Esomeprazole, Rabeprazole, Mild Cognitive Impairment

No Link Between Common Antibiotic, Irregular Heartbeat

Posted 18 Apr 2017 by Drugs.com

TUESDAY, April 18, 2017 – The widely used antibiotic azithromycin doesn't increase the risk of an abnormal heart rhythm, a new study finds. Azithromycin (Zithromax) is often used to treat respiratory and urinary tract infections. It belongs to a class of drugs known as macrolides. Another type of macrolide called erythromycin can disrupt the heart's normal rhythm. That antibiotic has been linked to a potentially life-threatening heart condition called ventricular arrhythmia. Recent studies have reached conflicting conclusions about whether azithromycin is also linked to an increased risk of death from that condition. In an effort to clarify the issue, researchers analyzed data from more than 14 million new antibiotic users. The patients were located in Denmark, Germany, Italy, the Netherlands and the United Kingdom. The study found that 0.1 percent developed ventricular arrhythmia. ... Read more

Related support groups: Amoxicillin, Azithromycin, Arrhythmia, Augmentin, Zithromax, Erythromycin, Amoxicillin/Clavulanate, Amoxil, Zithromax Z-Pak, Z-Pak, Prevpac, MY-E, Ventricular Arrhythmia, Azasite, A/T/S, Amoxil Pediatric Drops, Amoclan, Amoxicillin/Clarithromycin/Lansoprazole, Benzoyl Peroxide/Erythromycin, Azithromycin Dose Pack

Are Heartburn Meds During Pregnancy Linked to Asthma in Kids?

Posted 9 Jan 2017 by Drugs.com

MONDAY, Jan. 9, 2017 – Women who take certain heartburn medications during pregnancy may have a child at increased risk of developing asthma, new research suggests. For the new study, investigators analyzed eight studies that included more than 1.3 million children. The researchers found that kids born to mothers who were prescribed drugs for acid reflux during pregnancy were at least one-third more likely to have been seen by a doctor for asthma symptoms. Some of the medications come from drug classes that include Tagamet, Zantac, Prilosec, Nexium and Pepcid. "Our study reports an association between the onset of asthma in children and their mothers' use of acid-suppressing medication during pregnancy," said researcher Dr. Aziz Sheikh. He's co-director of the Asthma UK Center for Applied Research, at the University of Edinburgh in Scotland. "It is important to stress that this ... Read more

Related support groups: GERD, Asthma, Omeprazole, Nexium, Prilosec, Zantac, Asthma - Maintenance, Indigestion, Pantoprazole, Protonix, Ranitidine, Dexilant, Pepcid, Lansoprazole, Prevacid, Delivery, Asthma - Acute, Duodenitis/Gastritis, Famotidine, Aciphex

Short Course of Antibiotics Not Best for Kids' Ear Infections

Posted 22 Dec 2016 by Drugs.com

WEDNESDAY, Dec. 21, 2016 – A shorter period of antibiotic treatment for ear infections in young children does more harm than good, a new study finds. About three-quarters of children have ear infections in their first year of life. These infections are the most common reason why children are given antibiotics, the University of Pittsburgh researchers noted. "Given significant concerns regarding overuse of antibiotics and increased antibiotic resistance, we conducted this trial to see if reducing the duration of antibiotic treatment would be equally effective along with decreased antibiotic resistance and fewer adverse reactions," Dr. Alejandro Hoberman said in a university news release. Hoberman is chief of the general academic pediatrics division at Children's Hospital of Pittsburgh of UPMC. The study included 520 youngsters with ear infections. The children ranged in age from 9 ... Read more

Related support groups: Amoxicillin, Augmentin, Otitis Media, Amoxicillin/Clavulanate, Amoxil, Prevpac, Amoclan, Amoxil Pediatric Drops, Amoxicillin/Clarithromycin/Lansoprazole, Augmentin XR, Augmentin ES-600, Tympanostomy Tubes, Biomox, Chronic Otitis Media, Otitis Media with Perforation of Ear Drum, Trimox, Moxatag, Omeclamox-Pak, Perforated Tympanic Membrane, Amoxicillin/clarithromycin/omeprazole

Could Common Heartburn Drugs Up Stroke Risk?

Posted 15 Nov 2016 by Drugs.com

TUESDAY, Nov. 15, 2016 – A popular category of heartburn medications – including Nexium, Prevacid, Prilosec and Protonix – may increase your risk of stroke, a new study suggests. Known as proton pump inhibitors (PPIs), these drugs increased people's overall stroke risk by 21 percent, said study lead author Dr. Thomas Sehested. However, the risk appears to be driven by people who take high doses, added Sehested, research director at the Danish Heart Foundation in Copenhagen. "People treated with a low dose of PPIs did not have a high risk of stroke," he said. "Those treated with the highest doses of PPIs had the highest risk of stroke." The extent of risk also depends on the specific PPI taken. At the highest dose, stroke risk ranged from 30 percent for lansoprazole (Prevacid) to 94 percent for pantoprazole (Protonix), the researchers said. Takeda Pharmaceutical, the maker of ... Read more

Related support groups: GERD, Ischemic Stroke, Heart Disease, Omeprazole, Nexium, Dementia, Prilosec, Zantac, Indigestion, Pantoprazole, Protonix, Alzheimer's Disease, Ranitidine, Transient Ischemic Attack, Dexilant, Pepcid, Lansoprazole, Prevacid, Barrett's Esophagus, Duodenitis/Gastritis

Common Heartburn Drugs Linked to Kidney Disease in Study

Posted 15 Apr 2016 by Drugs.com

THURSDAY, April 14, 2016 – People who use certain drugs for chronic heartburn may be at increased risk of developing kidney disease, a new study suggests. The research is the latest to highlight potential risks from drugs called proton pump inhibitors (PPIs). PPIs include prescription and over-the-counter drugs, such as Prilosec, Prevacid and Nexium. But prolonged use of PPIs has been linked to certain nutrient deficiencies and bone-density loss. According to the U.S. Food and Drug Administration, bone fractures are considered a safety concern when people use PPIs for a year or more. More recently, research has hinted at additional hazards. Last year, for example, a study tied the medications to a slight increase in heart attack risk. However, neither that study nor this new one prove that PPIs are directly to blame for these problems. "I cannot say for certain that this is ... Read more

Related support groups: GERD, Omeprazole, Prilosec, Pantoprazole, Protonix, Renal Failure, Barrett's Esophagus, Chronic Kidney Disease, Zegerid, Prilosec OTC, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide, Zegerid OTC, Protonix IV, Omeclamox-Pak, Renal and Genitourinary Disorders, Omesec, Amoxicillin/clarithromycin/omeprazole, Omeprazole/Sodium Bicarbonate

Antibiotic Resistance Common in Kids' Urinary Tract Infections

Posted 16 Mar 2016 by Drugs.com

WEDNESDAY, March 16, 2016 – Many kids who develop urinary tract infections tied to the E. coli bacteria are now failing to respond to antibiotic treatment, a new review warns. The culprit, according to the British researchers: Drug resistance, following years of over-prescribing and misusing antibiotics. "Antimicrobial resistance is an internationally recognized threat to health," noted study author Ashley Bryce, a doctoral fellow at the Center for Academic Primary Care at the University of Bristol in the U.K. And that threat is of particular concern among young patients, the authors said, given that E. coli-driven urinary tract infections (UTIs) are one of the most common forms of pediatric bacterial infections. Young children are more vulnerable to complications including kidney scarring and kidney failure, so they require prompt, appropriate treatment, added Bryce and co-author ... Read more

Related support groups: Urinary Tract Infection, Amoxicillin, Bactrim, Bladder Infection, Augmentin, Trimethoprim, Kidney Infections, Bactrim DS, Amoxicillin/Clavulanate, Sulfamethoxazole/Trimethoprim, Prevention of Bladder infection, Amoxil, Septra, Prevpac, SMZ-TMP DS, Sulfatrim, Septra DS, Cotrimoxazole, Cystitis Prophylaxis, Polytrim

Widely Used Heartburn Drugs Linked to Dementia Risk in Study

Posted 15 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more

Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Pantoprazole, Protonix, Alzheimer's Disease, Stomach Ulcer, Dexilant, Lansoprazole, Prevacid, Gastric Ulcer, Duodenitis/Gastritis, Peptic Ulcer, Aciphex, Esomeprazole, Rabeprazole

Scarlet Fever Resurfacing in Some Parts of the World

Posted 5 Nov 2015 by Drugs.com

THURSDAY, Nov. 5, 2015 – Scarlet fever, a childhood disease that had been largely relegated to the history books, is reappearing in some parts of the world, researchers warn. Outbreaks have been reported in the United Kingdom and Asia, said scientists at the Australian Infectious Diseases Center at the University of Queensland. "We have not yet had an outbreak in Australia, but over the past five years there have been more than 5,000 cases in Hong Kong [a 10-fold increase] and more than 100,000 cases in China," Mark Walker, a professor in the School of Chemistry and Molecular Biosciences, said in a university news release. "An outbreak in the U.K. has resulted in 12,000 cases since last year," he added. The research team used genetic sequencing to investigate the rise in scarlet fever-causing bacteria and its increasing resistance to antibiotics. The study was published online Nov. 2 ... Read more

Related support groups: Amoxicillin, Augmentin, Strep Throat, Amoxicillin/Clavulanate, Amoxil, Penicillin VK, Prevpac, Amoxicillin/Clarithromycin/Lansoprazole, Amoxil Pediatric Drops, Amoclan, Rheumatic Fever, Augmentin XR, Penicillin V Potassium, Biomox, Augmentin ES-600, Rheumatic Heart Disease, Moxatag, Pen-V, Omeclamox-Pak, Rheumatic Fever Prophylaxis

Study Sees No Link Between Antibiotics in Early Pregnancy and Birth Defects

Posted 30 Oct 2015 by Drugs.com

FRIDAY, Oct. 30, 2015 – A new Canadian study did not find any association between two common types of antibiotics taken during pregnancy and a higher risk of adverse effects to the baby. Four out of 10 pregnant women are prescribed antibiotics, with azithromycin and clarithromycin being the most common. They belong to a class of drugs called macrolides. "With penicillin, macrolides are amongst the most used medications in the general population and in pregnancy. However, debate remained on whether it is the infections or in fact the macrolides used to treat them that put women and their unborn child at greater risk of adverse pregnancy outcomes, including birth defects," said study co-leader Anick Berard, a professor of pharmacy at the University of Montreal. "We therefore aimed to estimate the risk of major congenital malformations after fetal exposure to the two most commonly used ... Read more

Related support groups: Birth Control, Contraception, Azithromycin, Zithromax, Clarithromycin, Biaxin, Delivery, Zithromax Z-Pak, Z-Pak, Prevpac, Azasite, Amoxicillin/Clarithromycin/Lansoprazole, Biaxin XL, Labor Pain, Azithromycin Dose Pack, Zithromax IV, Biaxin Filmtab, Zithromax TRI-PAK, Azithromycin/Trovafloxacin, Zmax

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