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TB Cases Falling for Foreign-Born People in U.S.

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Tuberculosis cases among foreign-born people in the United States fell by one-fifth in recent years, and the reasons for the decline depend on people's country of origin, a new study suggests. Tuberculosis (TB) is a bacterial infection affecting the lungs and sometimes other organs. Overall, TB cases in the United States decreased over the past two decades, but TB cases among foreign-born people remained higher than in the general population, the study authors said. Between 2007 and 2011, there was a 19 percent drop in TB cases among all foreign-born people in the nation, according to researchers from the U.S. Centers for Disease Control and Prevention. TB cases declined in people recently arriving from Mexico, China, India, the Philippines and Vietnam – the five countries that account for most of the foreign-born people with TB in the United States, the ... Read more

Related support groups: Isoniazid, Tuberculosis, Rifampin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Rifamate, Rifabutin, Isoniazid/Rifampin, Rifater, Mycobutin, Tuberculosis - Resistant, Rifadin, Tuberculous Meningitis, Tuberculosis - Urinary Tract, Isoniazid/Pyrazinamide/Rifampin, Rimactane, IsonaRif

Drug Makers, Governments Sign Deal to Fight Drug-Resistant Infections

Posted 21 Jan 2016 by Drugs.com

A groundbreaking agreement between the drug industry and governments to work together to fight drug-resistant "superbugs" is expected to be announced Thursday. Under the deal, 74 drug makers, 11 diagnostic test makers, and nine industry groups pledge to work with each other and 16 countries to prevent and improve treatment of drug-resistant infections, the Associated Press reported. These infections are a serious threat to millions of people worldwide and a number of factors contribute to the problem, including overuse of antibiotics, declining drug industry research, and few new medicines to combat bacteria, viruses, parasites and fungi. The new deal – scheduled to be announced at the World Economic Forum in Davos, Switzerland – is the first to outline how the drug industry and governments should team up to prevent more drugs from becoming ineffective, to spur development of new ... Read more

Related support groups: Doxycycline, Cephalexin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Sulfamethoxazole, Minocycline, Lamisil, Nystatin, Levofloxacin, Bactrim DS, Cefdinir, Terbinafine, Tetracycline, Avelox, Sulfamethoxazole/Trimethoprim, Cefuroxime, Sulfasalazine

E-Pillboxes Improve Medication Adherence, Study Finds

Posted 15 Sep 2015 by Drugs.com

TUESDAY, Sept. 15, 2015 – Electronic reminders may help people with tuberculosis take their medication properly, a new study suggests. Tuberculosis (TB) patients are less likely to miss doses when they receive alerts from an electronic pillbox, researchers report in the Sept. 15 issue of PLOS Medicine. Electronic pillboxes use visual, audio and/or vibration cues to signal when it's time to take medication. TB is a bacterial infection that mainly strikes the lungs. The traditional method of ensuring medical adherence in TB patients is to watch people take their medicine, but the study authors said this isn't doable in remote areas such as rural China. "Innovative approaches to enable patients to adhere to TB treatment are needed. Widespread use of medication monitors in national TB control programs can benefit from the development of a low-cost and reliable medication monitor as well as ... Read more

Related support groups: Isoniazid, Tuberculosis, Rifampin, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Tuberculosis - Extrapulmonary, Rifamate, Isoniazid/Rifampin, Rifabutin, Rifater, Myambutol, Rifadin, Mycobutin, Rifadin IV, Rifapentine, Isoniazid/Pyrazinamide/Rifampin, Nydrazid

Shortage of Key Drug Hampering U.S. Efforts to Control TB: Report

Posted 23 May 2013 by Drugs.com

THURSDAY, May 23 – A shortage of a critical tuberculosis drug has hampered the efforts of health departments across the United States to contain the spread of the highly infectious lung disease, federal officials report. The drug, isoniazid (INH), was first used in 1951 and is one of four drugs considered to be the core of any first-line treatment for tuberculosis (TB). Patients must take the drugs for six to nine months, according to the U.S. Centers for Disease Control and Prevention. However, a national survey of local health departments around the country in January found that many health departments and clinics were having trouble getting INH. According to the report, published in the May 24 issue of the CDC publication, Morbidity and Mortality Weekly Report, the shortage first became severe in November 2012 and was attributed to manufacturing and supply problems. The January ... Read more

Related support groups: Isoniazid, Tuberculosis, Nydrazid

New Medicine Might Fight Drug-Resistant TB, Study Says

Posted 6 Jun 2012 by Drugs.com

WEDNESDAY, June 6 – More than four decades after the last introduction of fresh treatments for tuberculosis, a new medication for multidrug-resistant strains of the global scourge has shown promise in a multinational trial. Scientists in nine countries tested delamanid – which inhibits the production of mycolic acid, a key component of tuberculosis (TB) bacteria. In a phase 2 trial with 481 patients, the drug cleared TB from the sputum cultures of nearly half the patients within two months, the study said. "I think it's very important that we have, in delamanid, the potential for a new drug in the first class of new drugs in 40 years," said study co-author Lawrence Geiter, vice president of global clinical development for Otsuka Pharmaceutical Co., the Tokyo-based developer of delamanid. "It's going to enhance treatment options." The study is published June 7 in the New England ... Read more

Related support groups: Isoniazid, Tuberculosis, Rifampin, Rifadin, Rimactane, Nydrazid, Rifadin IV

CDC Issues New TB Treatment Guidelines

Posted 8 Dec 2011 by Drugs.com

THURSDAY, Dec. 8 – New guidelines on treating so-called "latent" tuberculosis infection in the United States should significantly shorten and simplify the course of the therapy from about 9 months to 3 months, according to the U.S. Centers for Disease Control and Prevention. The new guidelines for public health officials and health care providers – which are based on expert opinion and the results of three clinical trials – are a "game changer" for the treatment of TB in the United States, according to CDC Director Dr. Thomas Frieden. Latent TB infection occurs when a person is infected with TB bacteria but does not yet have symptoms and so cannot transmit the bacteria to others. However, if the bacteria becomes active, the person will develop the disease and can also spread it to others. Certain people, including those with weakened immune systems, are more likely to progress from ... Read more

Related support groups: Isoniazid, Tuberculosis, Tuberculosis - Latent, Priftin, Rifapentine, Nydrazid

TB Outbreaks in Texas Schools Show Disease Still a Threat

Posted 14 Oct 2011 by Drugs.com

FRIDAY, Oct. 14 – Outbreaks among young people in Texas of the old foe tuberculosis – often mistakenly dismissed as a long-ago health menace now confined to the pages of a Charles Dickens novel – show that the respiratory disease is still easily contracted and remains a potential threat to Americans, experts say. "Tuberculosis has always been with us and probably always will be," said Dr. Len Horovitz, a pulmonary specialist with Lenox Hill Hospital in New York City. At least 100 people have tested positive for tuberculosis (TB) on skin tests in Ennis, Texas, about 40 miles south of Dallas, including several students at the local high school. The testing was done after a teacher was diagnosed with TB before the start of the school year. And the University of North Texas in Denton – about 70 miles away – recommended that 27 people who had had contact with a student diagnosed with a ... Read more

Related support groups: Isoniazid, Tuberculosis, Rifampin, Ethambutol, Pyrazinamide, Myambutol, Rifadin, Nydrazid, Rifadin IV, Rimactane

New Combo Therapy May Prevent TB, Save Lives in People With HIV

Posted 6 Jul 2011 by Drugs.com

WEDNESDAY, July 6 – Simpler and shorter treatment with antibiotic drugs could help prevent full-blown tuberculosis in millions of people worldwide infected with the bacterium that causes TB, especially those also infected with HIV, researchers report. TB, or tuberculosis, is the leading cause of death among people co-infected with HIV, the virus that causes AIDS. About half a million people with both infections die worldwide every year. The new study by an international team of scientists included 1,148 South African men and women infected with the TB bacterium and HIV, who were followed for up to six years to see whose TB infections stayed dormant. It found that the most streamlined combination treatment – a high dose of 900 milligrams each of the newer antibiotic rifapentine (Priftin) and the traditional anti-TB antibiotic isoniazid once weekly for three months – worked as well or ... Read more

Related support groups: Isoniazid, Tuberculosis - Prophylaxis, Priftin, Nydrazid, Rifapentine

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Tuberculosis - Latent, Tuberculosis - Prophylaxis, Tuberculosis - Active, Mycobacterium kansasii

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