Skip to Content

Join the 'NSAID-Induced Ulcer Prophylaxis' group to help and get support from people like you.

NSAID-Induced Ulcer Prophylaxis News

Common Heartburn Meds Show Ties to Kidney Trouble

Posted 12 days ago by Drugs.com

SATURDAY, Nov. 4, 2017 – If you're one of the millions of Americans who takes one of a class of anti-reflux meds such as Nexium, Prilosec and Prevacid, take heed: These drugs have been linked to higher odds of kidney trouble. The study couldn't prove cause-and-effect – it's possible that folks who need these heartburn medicines are simply more prone to kidney disease for other reasons. But the review of data did show a link. The medicines in question are called proton pump inhibitors (PPIs). They reduce stomach acid production and are among the most widely prescribed medications in the world. According to a team led by Dr. Charat Thongprayoon, of Bassett Medical Center in Cooperstown, N.Y., recent research has suggested an increased risk of kidney problems for people who take the drugs, but those findings were inconsistent. Probing deeper, the researchers reviewed data from five ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Indigestion, Renal Failure, Lansoprazole, Prevacid, Barrett's Esophagus, Chronic Kidney Disease, Duodenitis/Gastritis, Esomeprazole, Vimovo, Zegerid, Prevpac, Prilosec OTC, Amoxicillin/Clarithromycin/Lansoprazole, NSAID-Induced Ulcer Prophylaxis, Zegerid OTC, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide

Are Some Heartburn Meds Tied to Stomach Cancer?

Posted 16 days ago by Drugs.com

TUESDAY, Oct. 31, 2017 – Popping certain heartburn drugs like they're candy might up your odds for stomach cancer, new research suggests. The risk was proportionate to how long and how often these drugs, called proton pump inhibitors (PPIs), were taken. That risk increased anywhere from two to eight times, the study authors said. Although the relative risk seems high, the absolute risk was small. But it was statistically significant, especially for people infected with Helicobacter pylori, a bacteria linked to stomach cancer, the researchers explained. "While PPIs are one of the most commonly used medications for treating reflux disease as well as dyspepsia, clinicians should exercise caution when prescribing long-term PPIs, even to patients who have H. pylori eradicated," said lead researcher Dr. Wai Keung Leung. He is a professor of gastroenterology at the University of Hong Kong. ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Zantac, Pantoprazole, Protonix, Indigestion, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Barrett's Esophagus, Duodenitis/Gastritis, Famotidine, Aciphex, Heartburn Relief, Rabeprazole, Esomeprazole

Can Your Heartburn Meds Shorten Your Life?

Posted 4 Jul 2017 by Drugs.com

MONDAY, July 3, 2017 – Popular heartburn medications like Nexium, Prilosec or Prevacid may increase your risk of early death when taken for extended periods, a new study suggests. Further, the longer you take these drugs, known as proton pump inhibitors (PPIs), the greater your risk of early death, said senior researcher Dr. Ziyad Al-Aly. He is a kidney specialist and assistant professor of medicine with the Washington University School of Medicine, in St. Louis. "There was a relationship between duration of use and risk of death," Al-Aly said. "More prolonged use was associated with even higher risk." That said, Al-Aly pointed out that some patients really do need to take PPIs to deal with medical issues, even long-term. "Proton pump inhibitors actually save lives," Al-Aly said. "We don't want to leave people with a scary message. If you need this drug and you're under guidance of a ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Indigestion, Protonix, Dexilant, Gastrointestinal Disorders, Lansoprazole, Prevacid, Barrett's Esophagus, Duodenitis/Gastritis, Aciphex, Rabeprazole, Esomeprazole, Zegerid, Prilosec OTC, Dexlansoprazole, Protonix IV

FDA Approves Yosprala (aspirin and omeprazole) for Secondary Prevention of Cardiovascular Disease in Patients at Risk for Aspirin-Associated Gastric Ulcers

Posted 16 Sep 2016 by Drugs.com

MISSISSAUGA, Ontario, Sept. 15, 2016 /PRNewswire/ – Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ) (TSX: ARZ), a global specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration (FDA) has approved once-daily Yosprala, the only prescription fixed-dose combination of aspirin, an anti-platelet agent, and omeprazole, a proton pump inhibitor (PPI) in the U.S. Yosprala is indicated for patients who require aspirin for secondary prevention of cardiovascular (CV) and cerebrovascular events and who are at risk of developing aspirin associated gastric ulcers. The Company is expanding its U.S. sales force by 85 representatives in September to a total of 110 high quality sales representatives and plans to begin the U.S. promotional launch of Yosprala the first week in October. "Daily aspirin is a standard of care for secondary cardiovascular event prevention, but ... Read more

Related support groups: Aspirin, Omeprazole, Prevention of Cardiovascular Disease, NSAID-Induced Ulcer Prophylaxis, Yosprala, Aspirin/omeprazole, Gastric Ulcer Prophylaxis

Beware of Bleeding Risks With Antacids Containing Aspirin

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Antacids that contain aspirin may cause stomach or intestinal bleeding in rare cases, U.S. Food and Drug Administration officials said Monday. Since it issued a warning about serious bleeding risk with aspirin in 2009, the FDA has recorded eight new cases of serious bleeding caused by aspirin-containing antacid products sold over-the-counter, which include Alka Seltzer and Bromo Seltzer. In some of those cases, patients required a blood transfusion, the agency said in a news release. "Take a close look at the Drug Facts label, and if the product has aspirin, consider choosing something else for your stomach symptoms," Dr. Karen Murry Mahoney, deputy director of the division of nonprescription drug products, said in the release. "Unless people read the Drug Facts label when they're looking for stomach symptom relief, they might not even think about the possibility ... Read more

Related support groups: GERD, Aspirin, Ibuprofen, Naproxen, Advil, Aleve, Alcohol Dependence, Indigestion, Motrin, Excedrin, Alcoholism, Tums, Milk of Magnesia, Alka-Seltzer, Duodenitis/Gastritis, Vicoprofen, Aggrenox, Fiorinal, Excedrin Migraine, Caltrate

Clues to How Popular Heartburn Drug Might Harm Arteries

Posted 10 May 2016 by Drugs.com

TUESDAY, May 10, 2016 – A popular over-the-counter heartburn medication accelerated aging of blood vessel cells in lab tests, raising red flags about its long-term effect on heart health, researchers say. Faster aging of blood vessel cells exposed to the antacid Nexium (esomeprazole) might potentially hinder the tasks these cells perform to prevent heart attack and stroke, the new study suggests. These lab results could explain why other studies have shown increased risk of heart disease in people who use proton pump inhibitors (PPIs) – the class of heartburn medication that includes Nexium, said study senior author Dr. John Cooke. "Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure," said Cooke, chair of cardiovascular sciences at the ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Indigestion, Dexilant, Lansoprazole, Prevacid, Tums, Milk of Magnesia, Duodenitis/Gastritis, Aciphex, Caltrate, Esomeprazole, Rabeprazole, Prevention of Cardiovascular Disease, Calcium Carbonate, Phillips' Milk of Magnesia

Health Tip: Identifying Symptoms of GERD

Posted 24 Jun 2015 by Drugs.com

-- Gastroesophageal reflux disease (GERD) occurs when stomach acids back up into the esophagus. The U.S. National Institute of Diabetes and Digestive and Kidney Diseases mentions these symptoms: Having heartburn. Tasting stomach acid or food in the back of the mouth. Having bad breath. Feeling nauseated, or vomiting. Having difficulty breathing or swallowing. Wearing of tooth enamel. Read more

Related support groups: GERD, Indigestion, Helicobacter Pylori Infection, Barrett's Esophagus, Duodenitis/Gastritis, Erosive Gastritis, NSAID-Induced Ulcer Prophylaxis, Hypersecretory Conditions

FDA Approved Vimovo for Arthritis Patients At Risk of Developing NSAID-Associated Gastric Ulcers

Posted 3 May 2010 by Drugs.com

WILMINGTON, Del., April 30 /PRNewswire-FirstCall/ – AstraZeneca and Pozen Inc. today announced the U.S. Food and Drug Administration (FDA) has approved Vimovo (naproxen and esomeprazole magnesium) delayed-release tablets for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.(1) Vimovo, co-developed by Pozen Inc. and AstraZeneca, is a fixed-dose combination of enteric-coated naproxen, a pain-relieving non-steroidal anti-inflammatory drug (NSAID), and immediate-release esomeprazole, a proton pump inhibitor (PPI). The FDA approval was supported by data from a clinical development program, including results from the pivotal PN400-301 and PN400-302 studies, which showed patients taking Vimovo experienced significantly ... Read more

Related support groups: Rheumatoid Arthritis, Osteoarthritis, Naproxen, Ankylosing Spondylitis, Esomeprazole, NSAID-Induced Ulcer Prophylaxis

Ask a Question

Further Information

Related Condition Support Groups

Indigestion

Related Drug Support Groups

misoprostol, Cytotec, lansoprazole, Prevacid, Vimovo, Duexis, esomeprazole / naproxen, Prevacid SoluTab, Prevacid OTC, famotidine / ibuprofen, Prevacid IV